breseq  version 0.39.0  
mutation predictions | marginal predictions | summary statistics | genome diff | command line log

Predicted mutations
evidence position mutation annotation gene description
RA 5,666 C→T intergenic (+136/+17) yaaX → / ← yaaA DUF2502 domain‑containing protein YaaX/DNA binding and peroxide stress response protein YaaA
RA 44,202 C→T A8V (GCC→GTC)  fixC → putative oxidoreductase FixC
RA 46,673 C→T S289S (AGC→AGT yaaU → putative transporter YaaU
JC JC 59,123 IS150 (+) +3 bp coding (3‑5/159 nt) yabQ → protein YabQ
RA 92,790 C→T P460S (CCG→TCG)  ftsI → peptidoglycan DD‑transpeptidase FtsI
RA 143,021 A→G G81G (GGA→GGG yadG → putative ABC transporter ATP‑binding protein YadG
JC JC 214,173 IS2 (–) +5 bp intergenic (‑48/‑114) yaeP ← / → yaeQ PF06786 family protein YaeP/uncharacterized protein YaeQ
RA 238,884 G→A intergenic (‑148/+535) ykfM ← / ← yafV uncharacterized protein YkfM/2‑oxoglutaramate amidase
RA 239,930 G→A S87F (TCT→TTT)  yafV ← 2‑oxoglutaramate amidase
RA 243,084 G→A R74C (CGC→TGC)  fadE ← acyl‑CoA dehydrogenase
RA 245,766 G→A P14S (CCG→TCG)  dpaA ← peptidoglycan meso‑diaminopimelic acid protein amidase A
RA 246,747 G→T S12S (TCG→TCT yafL → NlpC/P60 family protein YafL
RA 251,604 G→A S236N (AGC→AAC)  dinB → DNA polymerase IV
RA 252,349 G→A E17K (GAA→AAA)  yafO → ribosome‑dependent mRNA interferase toxin YafO
RA 253,835 G→A intergenic (+674/+424) yafP → / ← pepD putative N‑acetyltransferase YafP/peptidase D
RA 266,523 G→A L11L (CTG→TTG)  yafY ← inner membrane lipoprotein YafY
RA 267,149 G→A intergenic (‑596/+35) yafY ← / ← yafZ inner membrane lipoprotein YafY/DUF932 domain‑containing protein YafZ
RA 268,709 G→A R84R (CGC→CGT ykfA ← putative GTP‑binding protein YkfA
RA 273,167 G→A R107R (CGG→CGA ykfC → PF00078 domain‑containing protein YkfC
RA 273,450 G→A A202T (GCG→ACG)  ykfC → PF00078 domain‑containing protein YkfC
RA 273,734 G→A Q296Q (CAG→CAA ykfC → PF00078 domain‑containing protein YkfC
RA 274,939 G→A A48V (GCT→GTT)  insH1 ← IS5 family transposase and trans‑activator
RA 274,985 G→A P33S (CCA→TCA)  insH1 ← IS5 family transposase and trans‑activator
RA 275,668 G→A G115E (GGA→GAA)  mmuP → S‑methyl‑L‑methionine transporter
RA 277,277 G→A R188H (CGT→CAT)  mmuM → homocysteine S‑methyltransferase
RA 281,053 T→C T311A (ACG→GCG)  yagA ← integrase core domain‑containing protein YagA
RA 281,778 G→A S69F (TCC→TTC)  yagA ← integrase core domain‑containing protein YagA
RA 284,535 T→G A445A (GCT→GCG yagF → D‑xylonate dehydratase
RA 285,966 G→A G191D (GGC→GAC)  yagG → putative D‑xylonate transporter YagG
RA 287,324 G→A G179D (GGC→GAC)  yagH → putative xylosidase/arabinosidase
RA 287,348 G→A G187D (GGC→GAC)  yagH → putative xylosidase/arabinosidase
RA 287,946 G→A W386* (TGG→TGA yagH → putative xylosidase/arabinosidase
RA 288,641 G→A A174A (GCC→GCT xynR ← DNA‑binding transcriptional repressor XynR
RA 305,439 G→A S460F (TCC→TTC)  ecpD ← fimbrial adhesin EcpD
RA 305,990 G→A I276I (ATC→ATT ecpD ← fimbrial adhesin EcpD
RA 308,924 G→A R137C (CGC→TGC)  ecpC ← putative fimbrial usher protein EcpC
RA 313,543 G→A intergenic (‑301/‑1748) ykgR ← / → insE1 putative membrane protein YkgR/IS3 element protein InsE
RA 314,622 G→A intergenic (‑1380/‑669) ykgR ← / → insE1 putative membrane protein YkgR/IS3 element protein InsE
RA 316,519 G→A intergenic (+66/+1207) insF1 → / ← rclC IS3 element protein InsF/DUF417 domain‑containing inner membrane protein RclC
RA 316,837 G→A intergenic (+384/+889) insF1 → / ← rclC IS3 element protein InsF/DUF417 domain‑containing inner membrane protein RclC
RA 320,300 G→A S25N (AGT→AAT)  rclR → DNA‑binding transcriptional activator RclR
RA 328,598 C→T V46I (GTC→ATC)  betB ← betaine aldehyde dehydrogenase
RA 339,376 G→A G351E (GGG→GAG)  yahG → DUF1116 domain‑containing protein YahG
RA 339,935 C→T A56V (GCC→GTC)  yahH → putative uncharacterized protein YahH
RA 339,941 C→T T58I (ACT→ATT)  yahH → putative uncharacterized protein YahH
RA 339,958 G→A D64N (GAC→AAC)  yahH → putative uncharacterized protein YahH
RA 343,442 G→A G187R (GGA→AGA)  yahK → aldehyde reductase, NADPH‑dependent
RA 347,833 G→A A204V (GCC→GTC)  prpR ← DNA‑binding transcriptional dual regulator PrpR
RA 352,850 G→A G49S (GGC→AGC)  prpE → propionyl‑CoA synthetase
RA 353,100 G→A G132D (GGC→GAC)  prpE → propionyl‑CoA synthetase
RA 355,006 G→A G29R (GGA→AGA)  codB → cytosine transporter
RA 355,064 G→A S48N (AGC→AAC)  codB → cytosine transporter
RA 355,229 G→A G103E (GGA→GAA)  codB → cytosine transporter
RA 357,285 G→A G372E (GGA→GAA)  codA → cytosine/isoguanine deaminase
RA 358,368 G→A P108L (CCC→CTC)  cynR ← DNA‑binding transcriptional dual regulator CynR
RA 360,082 G→A G31R (GGA→AGA)  cynX → cyanate transporter
RA 360,536 C→T S182F (TCC→TTC)  cynX → cyanate transporter
RA 360,786 G→A M265I (ATG→ATA cynX → cyanate transporter
RA 361,489 G→A N124N (AAC→AAT lacA ← galactoside O‑acetyltransferase
RA 364,433 G→A Q625* (CAG→TAG)  lacZ ← beta‑galactosidase
RA 365,146 G→A A387V (GCC→GTC)  lacZ ← beta‑galactosidase
RA 365,222 G→A P362S (CCT→TCT)  lacZ ← beta‑galactosidase
RA 365,959 G→A P116L (CCC→CTC)  lacZ ← beta‑galactosidase
RA 366,121 G→A A62V (GCC→GTC)  lacZ ← beta‑galactosidase
RA 372,529 G→A V139M (GTG→ATG)  mhpD → 2‑hydroxypentadienoate hydratase
RA 373,341 G→A A141T (GCG→ACG)  mhpF → acetaldehyde dehydrogenase (acetylating) MhpF
RA 373,985 C→T R40C (CGC→TGC)  mhpE → 4‑hydroxy‑2‑oxovalerate aldolase
RA 374,227 C→T A120A (GCC→GCT mhpE → 4‑hydroxy‑2‑oxovalerate aldolase
RA 380,022 (G)10→9 intergenic (‑141/+47) frmR ← / ← yaiO DNA‑binding transcriptional repressor FrmR/outer membrane protein YaiO
RA 382,571 G→A E300K (GAA→AAA)  insD1 → IS2 element protein
RA 382,943 G→A C331C (TGC→TGT yaiP ← putative glucosyltransferase
RA 384,839 G→A intergenic (‑223/‑393) yaiS ← / → tauA putative deacetylase YaiS/taurine ABC transporter periplasmic binding protein
RA 386,290 G→A E28E (GAG→GAA tauB → taurine ABC transporter ATP binding subunit
RA 387,624 G→A E218E (GAG→GAA tauC → taurine ABC transporter membrane subunit
RA 398,073 G→A G68R (GGG→AGG)  yaiW → surface‑exposed outer membrane lipoprotein
RA 398,494 G→A G208D (GGC→GAC)  yaiW → surface‑exposed outer membrane lipoprotein
RA 400,495 G→A V143V (GTC→GTT ddlA ← D‑alanine‑‑D‑alanine ligase A
RA 403,108 G→A L454L (CTG→CTA phoA → alkaline phosphatase
RA 431,516 A→C Y166* (TAT→TAG tsx ← nucleoside‑specific channel‑forming protein Tsx
RA 480,295 2 bp→AA coding (13‑14/219 nt) hha ← hemolysin expression‑modulating protein Hha
JC JC 480,334 IS5 (+) +4 bp coding (372‑375/375 nt) tomB ← Hha toxicity modulator TomB
JC JC 552,785 IS150 (+) +3 bp coding (314‑316/510 nt) purE ← N(5)‑carboxyaminoimidazole ribonucleotide mutase
JC JC 607,765 IS150 (+) +3 bp noncoding (26‑28/60 nt) sokE ← small RNA SokE
RA 640,502 C→A L250L (CTC→CTA ahpF → alkyl hydroperoxide reductase, AhpF component
RA 690,948 G→A V279V (GTC→GTT ybeX ← CorC‑HlyC family protein YbeX
RA 692,073 C→T R90H (CGT→CAT)  ybeY ← endoribonuclease YbeY
MC JC 696,507 Δ112 bp glnV glnV
RA 700,038 G→A H97Y (CAT→TAT)  umpH ← UMP phosphatase
RA 809,217 2 bp→AG coding (40‑41/1290 nt) bioA ← adenosylmethionine‑8‑amino‑7‑oxononanoate aminotransferase
RA 848,590 G→A P108S (CCG→TCG)  dps ← DNA protection during starvation protein
RA 968,837 G→A D158N (GAT→AAT)  lpxK → tetraacyldisaccharide 4'‑kinase
RA 1,018,193 C→T S36N (AGT→AAT)  ycbZ ← putative ATP‑dependent protease YcbZ
RA 1,022,002 C→T E628K (GAG→AAG)  yccS ← putative transporter YccS
RA 1,023,148 C→T D246N (GAT→AAT)  yccS ← putative transporter YccS
RA 1,034,465 C→T R404R (CGC→CGT hyaB → hydrogenase 1 large subunit
RA 1,035,862 C→T A31A (GCC→GCT hyaD → putative hydrogenase 1 maturation protease HyaD
RA 1,036,085 C→T L106L (CTG→TTG)  hyaD → putative hydrogenase 1 maturation protease HyaD
RA 1,037,810 C→T P24L (CCC→CTC)  appC → cytochrome bd‑II subunit 1
RA 1,040,126 G→T L277L (CTG→CTT appB → cytochrome bd‑II subunit 2
RA 1,043,376 C→T V279M (GTG→ATG)  etk ← protein‑tyrosine kinase Etk
RA 1,048,985 C→T L116L (CTG→CTA gfcB ← lipoprotein GfcB
RA 1,061,935 G→A S46N (AGC→AAC)  torD → trimethylamine‑N‑oxide reductase‑specific chaperone
RA 1,070,014 A→G L114P (CTG→CCG)  rutF ← FMN reductase RutF
RA 1,078,641 A→C F81C (TTT→TGT)  putA ← fused DNA‑binding transcriptional repressor/proline dehydrogenase/1‑pyrroline‑5‑carboxylate dehydrogenase PutA
MC JC 1,095,503 Δ10,047 bp IS3‑mediated ycdU[ymdA] ycdU, serX, ghrA, ycdX, ycdY, ycdZ, csgG, csgF, csgE, csgD, csgB, csgA, csgC, [ymdA]
RA 1,111,727 2 bp→TT coding (865‑866/2544 nt) opgH → osmoregulated periplasmic glucans biosynthesis protein H
JC JC 1,141,668 IS150 (+) +3 bp coding (2698‑2700/3186 nt) rne ← ribonuclease E
JC JC 1,145,135 IS3 (+) +3 bp coding (196‑198/960 nt) rluC → 23S rRNA pseudouridine(955/2504/2580) synthase
RA 1,150,616 C→T L297L (CTG→TTG)  fabD → [acyl‑carrier‑protein] S‑malonyltransferase
RA 1,169,836 A→G L180P (CTG→CCG)  ldtC ← L,D‑transpeptidase LdtC
RA 1,189,980 A→G T156T (ACT→ACC phoP ← DNA‑binding transcriptional dual regulator PhoP
RA 1,196,220 C→T H366H (CAC→CAT icd → isocitrate dehydrogenase
RA 1,196,232 C→T T370T (ACC→ACT icd → isocitrate dehydrogenase
RA 1,196,245 T→C L375M (TTA→CTG)  icd → isocitrate dehydrogenase
RA 1,196,247 A→G L375M (TTA→CTG icd → isocitrate dehydrogenase
RA 1,196,277 C→T N385N (AAC→AAT icd → isocitrate dehydrogenase
RA 1,196,280 G→C A386A (GCG→GCC icd → isocitrate dehydrogenase
RA 1,196,283 A→G K387K (AAA→AAG icd → isocitrate dehydrogenase
JC JC 1,232,148 IS2 (–) +5 bp coding (963‑967/1269 nt) umuC → DNA polymerase V catalytic protein
RA 1,265,552 G→A G181S (GGT→AGT)  prfA → peptide chain release factor RF1
RA 1,276,230 C→T P463P (CCG→CCA narX ← sensor histidine kinase NarX
MC JC 1,299,499 Δ1,199 bp insH21 insH21
JC JC 1,301,713 IS30 (–) +2 bp coding (532‑533/1632 nt) oppA → oligopeptide ABC transporter periplasmic binding protein
RA 1,301,992 A→T N271Y (AAT→TAT)  oppA → oligopeptide ABC transporter periplasmic binding protein
RA 1,306,736 T→G S325A (TCC→GCC)  oppF → murein tripeptide ABC transporter/oligopeptide ABC transporter ATP binding subunit OppF
RA 1,310,770 A→G H32H (CAT→CAC yciI ← protein YciI
RA 1,315,384 G→A Y129Y (TAC→TAT yciF ← DUF892 domain‑containing protein YciF
RA 1,317,129 G→A Q32* (CAG→TAG)  trpA ← tryptophan synthase subunit alpha
RA 1,322,325 G→A L208F (CTC→TTC)  trpE ← anthranilate synthase subunit TrpE
RA 1,337,394 A→G S522G (AGC→GGC)  acnA → aconitate hydratase 1
RA 1,356,932 G→A T60I (ACC→ATC)  sapA ← putative periplasmic binding protein SapA
RA 1,357,202 C→T intergenic (‑92/+221) sapA ← / ← ymjA putative periplasmic binding protein SapA/DUF2543 domain‑containing protein YmjA
RA 1,358,859 T→C Y110C (TAT→TGT)  puuP ← putrescine:H(+) symporter PuuP
RA 1,362,062 C→A T51K (ACG→AAG)  puuR → DNA‑binding transcriptional repressor PuuR
RA 1,366,433 G→A G295D (GGC→GAC)  puuE → 4‑aminobutyrate aminotransferase PuuE
MC JC 1,397,239 Δ7,448 bp IS5‑mediated ynaJabgA ynaJ, uspE, fnr, ogt, abgT, abgB, abgA
JC JC 1,477,100 IS5 (+) +4 bp coding (1957‑1960/2307 nt) ydbD → DUF2773 domain‑containing protein YdbD
RA 1,487,229 G→A intergenic (+266/‑6) hrpA → / → ydcF ATP‑dependent 3'‑>5' RNA helicase HrpA/DUF218 domain‑containing protein YdcF
RA 1,501,192 C→T P207L (CCT→CTT)  tehA → tellurite resistance protein
RA 1,506,659 G→A G163E (GGG→GAG)  sutR → DNA‑binding transcriptional dual regulator SutR
RA 1,530,720 G→A intergenic (‑216/‑1096) yncO ← / → ydcC protein YncO/H repeat‑associated putative transposase YdcC
RA 1,542,535 G→A A19V (GCC→GTC)  narZ ← nitrate reductase Z subunit alpha
RA 1,547,403 G→A M1M (ATG→ATA) † fdnG → formate dehydrogenase N subunit alpha
RA 1,549,651 G→A A751T (GCT→ACT)  fdnG → formate dehydrogenase N subunit alpha
RA 1,557,486 G→A L185L (CTG→TTG)  ddpF ← putative D,D‑dipeptide ABC transporter ATP‑binding subunit DdpF
RA 1,563,622 G→A S704S (TCC→TCT dosP ← oxygen‑sensing c‑di‑GMP phosphodiesterase DosP
RA 1,566,073 G→A V356V (GTC→GTT dosC ← diguanylate cyclase DosC
RA 1,573,791 G→A A471V (GCA→GTA)  pqqL ← periplasmic metalloprotease
RA 1,582,610 G→T intergenic (‑86/+316) ydeN ← / ← ydeO putative sulfatase YdeN/DNA‑binding transcriptional dual regulator YdeO
JC JC 1,590,147 IS2 (+) +5 bp intergenic (‑146/+703) ydeT ← / ← hipA fimbrial usher domain‑containing protein YdeT/serine/threonine‑protein kinase toxin HipA
RA 1,596,941 G→A intergenic (‑4499/+1676) hipB ← / ← lsrK antitoxin/DNA‑binding transcriptional repressor HipB/autoinducer‑2 kinase
RA 1,598,846 G→A A455V (GCC→GTC)  lsrK ← autoinducer‑2 kinase
RA 1,606,337 G→A E80K (GAA→AAA)  lsrF → 3‑hydroxy‑2,4‑pentadione 5‑phosphate thiolase
RA 1,607,592 G→A A83T (GCA→ACA)  tam → trans‑aconitate 2‑methyltransferase
RA 1,610,076 T→G D202A (GAT→GCT)  uxaB ← tagaturonate reductase
RA 1,643,679 A→T L209Q (CTG→CAG)  ydfU ← protein YdfU
RA 1,652,331 T→C intergenic (+2346/+397) ydfD → / ← ynfP lysis protein/protein YnfP
RA 1,684,231 G→A intergenic (+48/‑28) rstB → / → tus sensory histidine kinase RstB/DNA replication terminus site‑binding protein
RA 1,721,136 C→T L38F (CTT→TTT)  ydhI → DUF1656 domain‑containing protein YdhI
JC JC 1,772,062 IS5 (+) +4 bp coding (992‑995/1215 nt) ydiM → putative exporter YdiM
RA 1,776,715 A→T S377C (AGT→TGT)  ydiF → putative acetate‑CoA transferase YdiF
RA 1,803,487 G→A intergenic (‑917/‑1678) thrS ← / → yniD threonine‑‑tRNA ligase/uncharacterized protein YniD
RA 1,817,420 G→A L361L (CTG→TTG)  chbF ← monoacetylchitobiose‑6‑phosphate hydrolase
RA 1,824,540 C→T G133D (GGC→GAC)  ves ← HutD family protein Ves
JC JC 1,844,254 IS150 (+) +3 bp coding (616‑618/1041 nt) ynjI ← DUF1266 domain‑containing protein YnjI
RA 1,854,789 G→A V22V (GTC→GTT ydjF ← putative DNA‑binding transcriptional regulator YdjF
RA 1,856,844 C→T D29N (GAT→AAT)  ydjH ← L‑glycero‑L‑galacto‑octuluronate kinase
JC 1,867,696 Δ7 bp coding (789‑795/1935 nt) yeaG → protein kinase YeaG
RA 1,892,332 G→A P302S (CCG→TCG)  yoaA ← putative ATP‑dependent 5' to 3' DNA helicase
RA 1,894,839 T→C L12P (CTC→CCC)  pabB → aminodeoxychorismate synthase subunit 1
RA 1,899,122 G→A G232G (GGG→GGA pdeD → putative c‑di‑GMP phosphodiesterase PdeD
RA 1,902,255 G→A G70R (GGA→AGA)  manX → mannose‑specific PTS enzyme IIAB component
RA 1,907,092 G→A intergenic (‑32/+134) rlmA ← / ← cspC 23S rRNA m(1)G745 methyltransferase/transcription antiterminator and regulator of mRNA stability CspC
JC JC 1,907,451 IS2 (+) +5 bp coding (137‑141/144 nt) yobF ← DUF2527 domain‑containing protein YobF
RA 1,919,413 G→A G635E (GGG→GAG)  letB → lipophilic envelope spanning tunnel
RA 1,926,726 G→A D203N (GAC→AAC)  exoX → exonuclease X
RA 1,942,638 G→A intergenic (‑55/‑24) znuA ← / → znuC Zn(2(+)) ABC transporter periplasmic binding protein/Zn(2(+)) ABC transporter ATP binding subunit
RA 1,958,858 G→A L137F (CTT→TTT)  cutC ← PF03932 family protein CutC
RA 1,980,754 G→A H287Y (CAT→TAT)  otsA ← trehalose‑6‑phosphate synthase
RA 1,987,499 C→A intergenic (+71/+8) ftnB → / ← yecJ putative ferritin‑like protein/DUF2766 domain‑containing protein YecJ
RA 1,993,134 G→A P525S (CCC→TCC)  uvrC ← UvrABC excision nuclease subunit C
RA 2,001,282 G→A L170L (CTA→TTA)  fliA ← RNA polymerase sigma factor FliA
RA 2,007,206 G→A A351T (GCG→ACG)  amyA → alpha‑amylase
RA 2,014,838 G→A R537H (CGC→CAC)  fliF → flagellar basal‑body MS‑ring and collar protein
RA 2,029,111 G→A P86S (CCG→TCG)  yedI ← DUF808 domain‑containing inner membrane protein YedI
RA 2,029,147 G→A L74L (CTG→TTG)  yedI ← DUF808 domain‑containing inner membrane protein YedI
RA 2,040,433 C→A A319D (GCC→GAC)  msrP → protein‑L‑methionine sulfoxide reductase catalytic subunit MsrP
RA 2,105,022 G→A V21V (GTC→GTT wbbJ ← putative lipopolysaccharide biosynthesis O‑acetyl transferase WbbJ
RA 2,109,858 G→A S94F (TCC→TTC)  rfbC ← dTDP‑4‑dehydrorhamnose 3,5‑epimerase
RA 2,134,777 G→A A292A (GCC→GCT wzc ← protein‑tyrosine kinase Wzc
RA 2,136,412 G→A L278L (CTG→TTG)  wza ← outer membrane polysaccharide export protein Wza
RA 2,139,657 G→A intergenic (+172/+102) yegH → / ← asmA inner membrane protein YegH/putative assembly protein AsmA
RA 2,164,376 G→A S34N (AGC→AAC)  baeR → DNA‑binding transcriptional activator BaeR
RA 2,175,290 G→A S344S (AGC→AGT gatZ ← putative tagatose‑1,6‑bisphosphate aldolase 2 chaperone
RA 2,182,956 G→A R232R (CGC→CGT yegX ← putative glycosyl hydrolase YegX
RA 2,184,992 C→T G104S (GGT→AGT)  thiM ← hydroxyethylthiazole kinase
RA 2,188,087 T→C T110A (ACG→GCG)  yehA ← putative fimbrial adhesin YehA
RA 2,195,035 G→A A246T (GCG→ACG)  metG → methionine‑‑tRNA ligase
RA 2,280,101 C→T C128Y (TGC→TAC)  rsuA ← 16S rRNA pseudouridine(516) synthase
RA 2,285,197 C→T R274R (CGC→CGT lapC → lipopolysaccharide signal transducer LapC
RA 2,297,690 C→T L190L (CTG→CTA napC ← periplasmic nitrate reductase cytochrome c protein
JC JC 2,324,384 IS150 (+) +3 bp coding (276‑278/651 nt) atoA → acetyl‑CoA:acetoacetyl‑CoA transferase subunit beta
RA 2,384,808 C→T K305K (AAG→AAA yfbK ← IPR002035/DUF3520 domain‑containing protein YfbK
RA 2,410,419 G→A L312L (CTG→TTG)  yfbS ← putative transporter YfbS
RA 2,444,493 C→T D87N (GAT→AAT)  epmC ← EF‑P‑Lys34 hydroxylase
RA 2,476,547 C→T intergenic (+37/+147) torI → / ← dsdC prophage CPS‑53 recombination directionality factor and response regulator inhibitor/DNA‑binding transcriptional dual regulator DsdC
RA 2,482,255 G→A T362I (ACC→ATC)  emrK ← tripartite efflux pump membrane fusion protein EmrK
RA 2,484,827 C→T L152F (CTT→TTT)  evgS → sensor histidine kinase EvgS
MC JC 2,558,699 Δ6,790 bp intZ[eutA] intZ, yffL, yffM, yffN, yffO, yffP, yffQ, yffR, yffS, [eutA]
RA 2,572,542 G→A P322S (CCG→TCG)  eutD ← phosphate acetyltransferase EutD
RA 2,582,490 C→T L96L (TTG→TTA ypfG ← DUF1176 domain‑containing protein YpfG
RA 2,623,776 G→A E245K (GAG→AAG)  ppk → polyphosphate kinase
RA 2,730,889 G→A noncoding (269/1542 nt) rrsG ← 16S ribosomal RNA
JC JC 2,739,490 IS150 (+) +3 bp coding (578‑580/1122 nt) tyrA ← fused chorismate mutase/prephenate dehydrogenase
RA 2,747,449 C→T S116N (AGC→AAC)  ffh ← signal recognition particle protein component
RA 2,774,947 G→A G544S (GGT→AGT)  yfjW → uncharacterized protein YfjW
JC JC 2,913,392 IS2 (–) +5 bp coding (256‑260/2235 nt) relA ← GDP/GTP pyrophosphokinase
RA 2,926,292 C→T intergenic (+96/‑16) queF → / → ppnN 7‑cyano‑7‑deazaguanine reductase/nucleotide 5'‑monophosphate nucleosidase
RA 2,933,793 G→A intergenic (‑105/‑442) fucA ← / → fucP L‑fuculose‑phosphate aldolase/L‑fucose:H(+) symporter
RA 2,937,348 T→C Y589H (TAC→CAC)  fucI → L‑fucose isomerase
RA 2,938,770 T→C F435L (TTC→CTC)  fucK → L‑fuculokinase
RA 2,941,835 G→A Q245* (CAA→TAA)  gcvA ← DNA‑binding transcriptional dual regulator GcvA
RA 2,990,760 G→A intergenic (‑400/‑508) yqeK ← / → ygeG protein YqeK/TPR repeat‑containing putative chaperone YgeG
RA 2,991,238 G→T intergenic (‑878/‑30) yqeK ← / → ygeG protein YqeK/TPR repeat‑containing putative chaperone YgeG
JC JC 3,013,819 IS150 (+) +3 bp coding (419‑421/1626 nt) yqeB ← XdhC‑CoxI family protein YqeB
RA 3,088,010 2 bp→TT intergenic (+150/‑273) metK → / → galP methionine adenosyltransferase/galactose:H(+) symporter
RA 3,103,765 G→A P251P (CCG→CCA mutY → adenine DNA glycosylase
RA 3,108,369 C→T D263N (GAC→AAC)  speC ← constitutive ornithine decarboxylase
RA 3,110,945 C→T S61N (AGC→AAC)  yghD ← putative type II secretion system M‑type protein YghD
RA 3,111,094 C→T Q11Q (CAG→CAA yghD ← putative type II secretion system M‑type protein YghD
RA 3,112,212 G→A Q280* (CAG→TAG)  yghF ← putative type II secretion system C‑type protein YghF
RA 3,113,320 C→T G53E (GGA→GAA)  yghG ← lipoprotein YghG
RA 3,114,408 C→T intergenic (‑56/+142) pppA ← / ← yghJ prepilin peptidase/putative lipoprotein YghJ
RA 3,115,217 C→T W1299* (TGG→TAG)  yghJ ← putative lipoprotein YghJ
RA 3,115,379 C→T G1245D (GGT→GAT)  yghJ ← putative lipoprotein YghJ
RA 3,121,292 C→T intergenic (‑13/+342) glcA ← / ← glcB glycolate/lactate:H(+) symporter GlcA/malate synthase G
RA 3,121,816 C→T A664T (GCG→ACG)  glcB ← malate synthase G
RA 3,124,703 C→T A253T (GCG→ACG)  glcF ← glycolate dehydrogenase, putative iron‑sulfur subunit
MC JC 3,131,341 Δ18,049 bp IS5‑mediated [yghQ][yqhA] 19 genes
RA 3,157,803 G→A A52T (GCG→ACG)  yqhG → DUF3828 domain‑containing protein YqhG
RA 3,163,470 G→A I4I (ATC→ATT plsC ← 1‑acylglycerol‑3‑phosphate O‑acyltransferase PlsC
RA 3,166,108 G→A intergenic (‑135/+3) parC ← / ← ygiS DNA topoisomerase IV subunit A/putative deoxycholate binding periplasmic protein
RA 3,166,913 G→A A269V (GCG→GTG)  ygiS ← putative deoxycholate binding periplasmic protein
RA 3,167,825 G→A intergenic (‑107/+26) ygiS ← / ← mqsA putative deoxycholate binding periplasmic protein/antitoxin of the MqsRA toxin‑antitoxin system/DNA‑binding transcriptional repressor MqsA
RA 3,168,872 G→A R120R (CGC→CGT ygiV ← DNA‑binding transcriptional repressor YgiV
RA 3,180,826 G→A E136K (GAA→AAA)  ygiC → putative acid‑‑amine ligase YgiC
RA 3,190,080 G→A G67D (GGC→GAC)  yqiH → putative fimbrial chaperone YqiH
RA 3,196,842 G→A L934L (CTG→TTG)  glnE ← fused glutamine synthetase deadenylase/glutamine synthetase adenylyltransferase
RA 3,212,352 G→A G416S (GGC→AGC)  dnaG → DNA primase
RA 3,215,625 G→A noncoding (28/76 nt) ileX → tRNA‑Ile
RA 3,222,872 G→A W80* (TGG→TGA ebgA → evolved beta‑D‑galactosidase subunit alpha
RA 3,278,700 G→A intergenic (‑35/‑214) agaR ← / → kbaZ DNA‑binding transcriptional repressor AgaR/putative tagatose‑1,6‑bisphosphate aldolase 1 chaperone
RA 3,280,814 G→A intergenic (+124/‑1162) agaV → / → agaS N‑acetyl‑D‑galactosamine specific PTS enzyme IIB component/putative galactosamine‑6‑phosphate deaminase/isomerase
RA 3,284,611 G→A V148I (GTC→ATC)  agaB → galactosamine‑specific PTS enzyme IIB component
RA 3,294,210 G→A V271I (GTA→ATA)  lpoA → outer membrane lipoprotein ‑ activator of MrcA activity
RA 3,295,067 G→A M556I (ATG→ATA lpoA → outer membrane lipoprotein ‑ activator of MrcA activity
RA 3,295,290 G→A A631T (GCA→ACA)  lpoA → outer membrane lipoprotein ‑ activator of MrcA activity
RA 3,300,725 G→A P12S (CCG→TCG)  yhbS ← putative N‑acetyltransferase YhbS
RA 3,307,890 G→A A15V (GCC→GTC)  yrbN ← uncharacterized protein YrbN
RA 3,318,274 G→A noncoding (16/77 nt) metY ← tRNA‑Met
RA 3,323,624 G→A S149S (AGC→AGT glmM ← phosphoglucosamine mutase
RA 3,327,196 G→A P157S (CCA→TCA)  rlmE ← 23S rRNA 2'‑O‑ribose U2552 methyltransferase
JC JC 3,335,208 IS150 (+) +4 bp intergenic (+21/+24) sfsB → / ← murA putative transcriptional regulator SfsB/UDP‑N‑acetylglucosamine 1‑carboxyvinyltransferase
RA 3,336,411 2 bp→AT coding (83‑84/1260 nt) murA ← UDP‑N‑acetylglucosamine 1‑carboxyvinyltransferase
RA 3,347,801 G→A W229* (TGG→TGA rapZ → RNase adaptor protein RapZ
RA 3,348,518 G→A E23K (GAA→AAA)  yrbL → protein kinase‑like domain‑containing protein YrbL
RA 3,349,836 C→T L208L (CTG→CTA elbB ← low activity glyoxalase ElbB
RA 3,351,713 G→A S438F (TCT→TTT)  arcB ← sensor histidine kinase ArcB
RA 3,372,107 C→T G156G (GGG→GGA nanT ← N‑acetylneuraminate:H(+) symporter
RA 3,378,455 C→T G66D (GGC→GAC)  rplM ← 50S ribosomal subunit protein L13
RA 3,388,041 T→G T50P (ACG→CCG)  aaeB ← aromatic carboxylic acid efflux pump subunit AaeB
RA 3,414,646 C→T F261F (TTC→TTT acrE → multidrug efflux pump membrane fusion lipoprotein AcrE
JC JC 3,429,229 IS2 (+) +5 bp intergenic (‑467/‑3) rrsD ← / → yrdA 16S ribosomal RNA/hexapeptide repeat‑containing protein YrdA
RA 3,436,697 G→A E60E (GAG→GAA trkA → NAD‑binding component of Trk potassium transporters
RA 3,439,561 G→A intergenic (‑52/+55) yhdN ← / ← rplQ DUF1992 domain‑containing protein YhdN/50S ribosomal subunit protein L17
RA 3,451,505 G→A T60T (ACC→ACT rplW ← 50S ribosomal subunit protein L23
RA 3,458,230 G→A R618R (CGG→CGA gspD → Type II secretion system protein GspD
RA 3,459,867 G→A G17G (GGG→GGA gspF → Type II secretion system protein GspF
RA 3,463,308 G→A A129T (GCG→ACG)  gspK → Type II secretion system protein GspK
RA 3,474,425 T→C K43R (AAA→AGA)  rpsL ← 30S ribosomal subunit protein S12
RA 3,481,492 G→A W68* (TGG→TGA yheS → putative ATP‑binding protein YheS
RA 3,482,886 C→T P533L (CCA→CTA)  yheS → putative ATP‑binding protein YheS
RA 3,490,560 G→A G90G (GGC→GGT pabA ← aminodeoxychorismate synthase subunit 2
RA 3,507,161 C→T G59D (GGT→GAT)  yhfT ← uncharacterized protein YhfT
RA 3,537,383 C→T intergenic (+95/‑2) greB → / → yhgF transcription elongation factor GreB/putative RNA‑binding protein YhgF
JC JC 3,543,555 IS150 (–) +3 bp coding (389‑391/879 nt) rpnA → recombination‑promoting nuclease RpnA
RA 3,545,630 C→T R3C (CGT→TGT)  nfuA → iron‑sulfur cluster carrier protein NfuA
RA 3,549,802 C→T G90D (GGC→GAC)  malQ ← 4‑alpha‑glucanotransferase
RA 3,551,420 C→T A352T (GCG→ACG)  malP ← maltodextrin phosphorylase
RA 3,551,909 C→T D189N (GAC→AAC)  malP ← maltodextrin phosphorylase
RA 3,554,195 C→T L371L (CTG→TTG)  malT → DNA‑binding transcriptional activator MalT
RA 3,560,455 +G intergenic (+589/+167) rtcR → / ← glpG DNA‑binding transcriptional activator RtcR/rhomboid protease GlpG
RA 3,577,715 C→T intergenic (‑123/+16) gntK ← / ← gntR D‑gluconate kinase, thermostable/DNA‑binding transcriptional repressor GntR
RA 3,579,434 C→T G71D (GGT→GAT)  yhhW ← quercetin 2,3‑dioxygenase
RA 3,589,300 C→T G243D (GGC→GAC)  ugpE ← sn‑glycerol 3‑phosphate ABC transporter membrane subunit UgpE
RA 3,589,321 C→T G236E (GGG→GAG)  ugpE ← sn‑glycerol 3‑phosphate ABC transporter membrane subunit UgpE
RA 3,594,331 C→T E384K (GAA→AAA)  livM ← branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM
RA 3,605,559 C→T A18T (GCC→ACC)  yhhM ← DUF2500 domain‑containing protein YhhM
RA 3,607,928 C→T P493L (CCC→CTC)  zntA → Zn(2(+))/Cd(2(+))/Pb(2(+)) exporting P‑type ATPase
RA 3,609,228 C→T F4F (TTC→TTT yhhQ → queuosine precursor transporter
RA 3,613,891 C→T S75S (AGC→AGT nikA → Ni(2(+)) ABC transporter periplasmic binding protein
RA 3,618,704 C→T A39A (GCC→GCT nikR → DNA‑binding transcriptional repressor NikR
RA 3,622,465 C→T P1092S (CCG→TCG)  rhsB → rhs element protein RhsB
RA 3,624,014 C→T intergenic (+232/‑364) yhhH → / → yhhI PF15631 family protein YhhH/putative transposase
RA 3,628,866 C→T E225K (GAA→AAA)  rbbA ← ribosome‑associated ATPase
RA 3,629,921 C→T E228K (GAG→AAG)  yhiI ← putative membrane fusion protein YhiI
RA 3,630,852 C→T intergenic (‑74/+116) yhiY ← / ← yhiJ protein YhiY/DUF4049 domain‑containing protein YhiJ
RA 3,639,252 C→T intergenic (+111/+133) pitA → / ← uspB metal phosphate:H(+) symporter PitA/universal stress protein B
RA 3,643,643 C→T A514T (GCG→ACG)  prlC ← oligopeptidase A
RA 3,650,351 C→T P39S (CCA→TCA)  arsC → arsenate reductase
RA 3,655,280 C→T G208E (GGG→GAG)  yhiD ← inner membrane protein YhiD
RA 3,662,374 G→A S654N (AGC→AAC)  mdtF → multidrug efflux pump RND permease MdtF
RA 3,662,815 C→T A801V (GCC→GTC)  mdtF → multidrug efflux pump RND permease MdtF
RA 3,672,877 C→T A155V (GCC→GTC)  rcdB → putative DNA‑binding transcriptional regulator YhjC
RA 3,682,515 C→T M311I (ATG→ATA dctA ← C4 dicarboxylate/orotate:H(+) symporter
RA 3,682,654 C→T G265E (GGG→GAG)  dctA ← C4 dicarboxylate/orotate:H(+) symporter
RA 3,686,110 C→T G1022S (GGC→AGC)  bcsC ← cellulose synthase outer membrane channel
RA 3,702,034 G→A L279F (CTC→TTC)  dppF ← dipeptide ABC transporter ATP binding subunit DppF
RA 3,707,947 C→A intergenic (‑242/+669) dppA ← / ← proK dipeptide ABC transporter periplasmic binding protein/tRNA‑Pro
MC JC 3,708,467 Δ168 bp [proK] [proK]
RA 3,710,343 C→T G45S (GGC→AGC)  eptB ← phosphoethanolamine transferase EptB
RA 3,711,347 C→T V221I (GTA→ATA)  yhjX ← putative transporter YhjX
RA 3,721,115 G→A D146N (GAT→AAT)  insJ → insertion element IS150 protein InsA
RA 3,725,176 T→G E48A (GAG→GCG)  glyQ ← glycine‑‑tRNA ligase subunit alpha
RA 3,734,518 C→T R267C (CGC→TGC)  xylH → xylose ABC transporter membrane subunit
RA 3,736,852 C→T G109D (GGC→GAC)  bax ← putative glycoside hydrolase Bax
RA 3,737,907 C→T F137F (TTC→TTT malS → alpha‑amylase
RA 3,739,921 C→T P73S (CCA→TCA)  avtA → valine‑‑pyruvate aminotransferase
RA 3,740,157 C→T V151V (GTC→GTT avtA → valine‑‑pyruvate aminotransferase
RA 3,754,134 C→T A99T (GCC→ACC)  yiaW ← DUF3302 domain‑containing protein YiaW
RA 3,757,058 G→A A257V (GCT→GTT)  yiaY ← L‑threonine dehydrogenase
RA 3,759,817 G→A T15T (ACC→ACT selB ← selenocysteyl‑tRNA‑specific translation elongation factor
RA 3,761,230 G→A S7F (TCC→TTC)  selA ← selenocysteine synthase
RA 3,761,858 G→A P33L (CCC→CTC)  yibF ← glutathione transferase‑like protein YibF
RA 3,762,109 C→T intergenic (‑154/‑74) yibF ← / → rhsA glutathione transferase‑like protein YibF/rhs element protein RhsA
RA 3,767,891 C→T intergenic (+712/‑286) yibA → / → yibG putative lyase containing HEAT‑repeat/tetratricopeptide‑like domain‑containing protein YibG
RA 3,770,330 G→A Y350Y (TAC→TAT yibH ← inner membrane protein YibH
RA 3,771,979 G→T intergenic (‑235/‑302) yibI ← / → mtlA DUF3302 domain‑containing protein YibI/mannitol‑specific PTS enzyme IICBA component
RA 3,778,588 C→T T397I (ACC→ATC)  lldP → lactate/glycolate:H(+) symporter LldP
RA 3,778,752 C→T L452L (CTG→TTG)  lldP → lactate/glycolate:H(+) symporter LldP
RA 3,781,861 G→A T234T (ACC→ACT cysE ← serine acetyltransferase
RA 3,793,266 G→A P140S (CCT→TCT)  htrL ← protein HtrL
RA 3,815,883 +C coding (667/687 nt) rph ← truncated RNase PH
JC 3,822,651 (CAGGAT)1→2 coding (252/2109 nt) spoT → bifunctional (p)ppGpp synthase/hydrolase SpoT
RA 3,823,016 G→T R206L (CGC→CTC)  spoT → bifunctional (p)ppGpp synthase/hydrolase SpoT
RA 3,823,162 C→T H255Y (CAC→TAC)  spoT → bifunctional (p)ppGpp synthase/hydrolase SpoT
RA 3,854,009 G→A A30T (GCT→ACT)  emrD → multidrug efflux pump EmrD
RA 3,864,357 G→A L153L (CTG→CTA yidP → putative DNA‑binding transcriptional regulator YidP
RA 3,865,764 C→T G170G (GGG→GGA yidE ← putative transport protein YidE
RA 3,869,637 C→A L87L (CTC→CTA cbrA → colicin M resistance protein
RA 3,871,363 G→A P123L (CCG→CTG)  dgoT ← D‑galactonate:H(+) symporter
RA 3,873,892 G→A L195F (CTT→TTT)  dgoK ← 2‑dehydro‑3‑deoxygalactonokinase
RA 3,875,237 G→A intergenic (‑77/‑201) dgoR ← / → yidX DNA‑binding transcriptional regulator DgoR/putative lipoprotein YidX
RA 3,876,817 G→A P46S (CCG→TCG)  yidA ← sugar phosphatase YidA
RA 3,878,267 G→A A618V (GCT→GTT)  gyrB ← DNA gyrase subunit B
RA 3,878,536 G→A Y528Y (TAC→TAT gyrB ← DNA gyrase subunit B
RA 3,879,061 C→T M353I (ATG→ATA gyrB ← DNA gyrase subunit B
RA 3,883,818 G→A intergenic (‑89/‑208) dnaA ← / → ysdD chromosomal replication initiator protein DnaA/protein YsdD
RA 3,896,736 G→A intergenic (‑127/‑38) adeP ← / → yieH adenine:H(+) symporter/6‑phosphogluconate phosphatase
RA 3,898,481 G→A D154N (GAT→AAT)  cbrC → PF03691 family colicin E2 tolerance protein CbrC
RA 3,901,757 C→T G155D (GGT→GAT)  bglH ← carbohydrate‑specific outer membrane porin, cryptic
RA 3,902,025 G→A R66C (CGT→TGT)  bglH ← carbohydrate‑specific outer membrane porin, cryptic
RA 3,908,073 C→T Q98Q (CAG→CAA pstB ← phosphate ABC transporter ATP binding subunit
RA 3,911,379 C→T Q49Q (CAG→CAA pstS ← phosphate ABC transporter periplasmic binding protein
RA 3,912,074 G→A S532F (TCC→TTC)  glmS ← L‑glutamine‑‑D‑fructose‑6‑phosphate aminotransferase
RA 3,913,223 G→A A149V (GCT→GTT)  glmS ← L‑glutamine‑‑D‑fructose‑6‑phosphate aminotransferase
RA 3,915,731 G→A A81V (GCC→GTC)  atpC ← ATP synthase F1 complex subunit epsilon
RA 3,922,501 G→A intergenic (‑61/+556) atpI ← / ← rsmG ATP synthase accessory factor AtpI/16S rRNA m(7)G527 methyltransferase
RA 3,933,173 G→A V620I (GTC→ATC)  kup → K(+):H(+) symporter Kup
RA 3,941,924 G→A noncoding (117/1542 nt) rrsC → 16S ribosomal RNA
RA 3,949,381 C→T E197K (GAA→AAA)  yifB ← putative magnesium chelatase YifB
RA 3,951,292 C→T intergenic (+735/‑909) ilvX → / → ilvM uncharacterized protein IlvX/acetolactate synthase II subunit IlvM
RA 3,954,288 C→T L271L (CTG→TTG)  ilvD → dihydroxy‑acid dehydratase
RA 3,955,095 C→T L540L (CTG→TTG)  ilvD → dihydroxy‑acid dehydratase
RA 3,960,251 C→T intergenic (‑438/‑426) ppiC ← / → rep peptidyl‑prolyl cis‑trans isomerase C/ATP‑dependent DNA helicase Rep
RA 3,983,395 C→T G146G (GGC→GGT aslB → putative anaerobic sulfatase maturation enzyme AslB
RA 3,989,779 C→T S17N (AGC→AAC)  hemD ← uroporphyrinogen‑III synthase
RA 3,993,531 T→C R793R (CGT→CGC cyaA → adenylate cyclase
RA 3,996,049 T→A L156* (TTG→TAG)  yigA → DUF484 domain‑containing protein YigA
RA 4,001,659 C→T F78F (TTC→TTT corA → Ni(2(+))/Co(2(+))/Mg(2(+)) transporter
RA 4,006,024 C→T S54F (TCC→TTC)  recQ → ATP‑dependent DNA helicase RecQ
RA 4,011,802 C→T P243S (CCG→TCG)  bioP → biotin transporter
RA 4,013,019 C→T intergenic (‑203/‑34) metR ← / → metE DNA‑binding transcriptional dual regulator MetR/cobalamin‑independent homocysteine transmethylase
RA 4,032,682 C→T S64F (TCT→TTT)  yigZ → IMPACT family member YigZ
RA 4,036,933 C→T noncoding (1403/1542 nt) rrsA → 16S ribosomal RNA
RA 4,037,229 C→T intergenic (+12/‑31) ileT → / → alaT tRNA‑Ile/tRNA‑Ala
RA 4,037,875 C→T noncoding (357/2905 nt) rrlA → 23S ribosomal RNA
RA 4,044,246 C→T I16I (ATC→ATT yihF → DUF945 domain‑containing protein YihF
RA 4,054,463 C→T V272V (GTG→GTA glnG ← DNA‑binding transcriptional dual regulator NtrC
RA 4,056,080 C→T G87E (GGG→GAG)  glnL ← protein histidine kinase NtrB
RA 4,067,529 C→T G583D (GGC→GAC)  yihQ ← sulfoquinovosidase
RA 4,068,181 C→T E366K (GAG→AAG)  yihQ ← sulfoquinovosidase
RA 4,070,844 C→T E305K (GAA→AAA)  yihS ← sulfoquinovose isomerase
RA 4,083,333 C→T Q830Q (CAG→CAA fdoG ← formate dehydrogenase O subunit alpha
RA 4,084,903 T→G N307T (AAC→ACC)  fdoG ← formate dehydrogenase O subunit alpha
RA 4,092,703 A→G F41L (TTC→CTC)  frvA ← putative PTS enzyme IIA component FrvA
RA 4,093,564 C→T V237I (GTA→ATA)  rhaD ← rhamnulose‑1‑phosphate aldolase
RA 4,094,457 C→T intergenic (‑185/+266) rhaD ← / ← rhaA rhamnulose‑1‑phosphate aldolase/L‑rhamnose isomerase
RA 4,096,043 C→T S469N (AGT→AAT)  rhaB ← rhamnulokinase
RA 4,101,726 G→A G13R (GGG→AGG)  kdgT → 2‑dehydro‑3‑deoxy‑D‑gluconate:H(+) symporter
RA 4,113,851 G→A H208Y (CAT→TAT)  fpr ← flavodoxin/ferredoxin‑NADP(+) reductase
RA 4,117,947 C→T W48* (TGG→TGA glpF ← glycerol facilitator
RA 4,121,166 C→T E194E (GAG→GAA hslU ← ATPase component of the HslVU protease
RA 4,123,923 +A coding (534/1026 nt) cytR ← DNA‑binding transcriptional repressor CytR
RA 4,125,151 C→T V554I (GTT→ATT)  priA ← primosomal protein N'
RA 4,133,661 C→T intergenic (+155/‑174) metF → / → katG 5,10‑methylenetetrahydrofolate reductase/catalase/hydroperoxidase HPI
RA 4,143,134 C→T A202V (GCC→GTC)  frwC → putative PTS enzyme IIC component FrwC
RA 4,143,377 C→T S283L (TCA→TTA)  frwC → putative PTS enzyme IIC component FrwC
RA 4,147,160 C→T T8I (ACC→ATC)  frwD → putative PTS enzyme IIB component FrwD
RA 4,147,572 C→T S249N (AGC→AAC)  yijO ← putative DNA‑binding transcriptional regulator YijO
RA 4,161,248 G→T G61V (GGC→GTC)  fabR → DNA‑binding transcriptional repressor FabR
RA 4,164,123 C→G A162G (GCA→GGA)  btuB → cobalamin outer membrane transporter
RA 4,164,339 G→A W234* (TGG→TAG)  btuB → cobalamin outer membrane transporter
RA 4,164,868 G→A G410G (GGG→GGA btuB → cobalamin outer membrane transporter
RA 4,165,852 C→T S142F (TCT→TTT)  murI → glutamate racemase
RA 4,181,775 C→T I177I (ATC→ATT rpoB → RNA polymerase subunit beta
RA 4,188,732 C→T S1128F (TCC→TTC)  rpoC → RNA polymerase subunit beta'
RA 4,205,696 C→T G79D (GGC→GAC)  purD ← phosphoribosylamine‑‑glycine ligase
RA 4,212,931 C→T noncoding (2889/2904 nt) rrlE → 23S ribosomal RNA
RA 4,214,745 C→T P156S (CCT→TCT)  metA → homoserine O‑succinyltransferase
RA 4,215,142 G→A W288* (TGG→TAG)  metA → homoserine O‑succinyltransferase
RA 4,215,347 T→A intergenic (+138/‑131) metA → / → aceB homoserine O‑succinyltransferase/malate synthase A
RA 4,216,997 C→T A507V (GCC→GTC)  aceB → malate synthase A
RA 4,222,297 C→T S64N (AGC→AAC)  arpA ← regulator of acetyl CoA synthetase
RA 4,223,638 T→C intergenic (‑10/‑190) iclR ← / → metH DNA‑binding transcriptional repressor IclR/cobalamin‑dependent methionine synthase
RA 4,227,956 C→T L76L (CTG→TTG)  yjbB → putative inorganic phosphate export protein YjbB
RA 4,240,892 C→T A455T (GCA→ACA)  xylE ← D‑xylose:H(+) symporter
RA 4,243,309 C→T A70T (GCT→ACT)  malG ← maltose ABC transporter membrane subunit MalG
RA 4,244,133 C→T A315T (GCG→ACG)  malF ← maltose ABC transporter membrane subunit MalF
RA 4,246,490 C→T intergenic (‑71/‑294) malE ← / → malK maltose ABC transporter periplasmic binding protein/maltose ABC transporter ATP binding subunit
RA 4,267,249 C→T L46L (CTG→TTG)  tyrB → tyrosine aminotransferase
RA 4,278,534 C→T S19L (TCA→TTA)  ghxP → guanine/hypoxanthine transporter GhxP
RA 4,282,332 (A)5→6 coding (744/1293 nt) yjcF ← pentapeptide repeat‑containing protein YjcF
RA 4,293,781 2 bp→AT coding (239‑240/597 nt) nrfG → putative formate‑dependent nitrite reductase complex subunit NrfG
RA 4,295,008 C→T S176S (TCC→TCT gltP → glutamate/aspartate : H(+) symporter GltP
RA 4,296,381 +GC intergenic (+587/+55) gltP → / ← yjcO glutamate/aspartate : H(+) symporter GltP/Sel1 repeat‑containing protein YjcO
RA 4,302,088 G→A P331S (CCA→TCA)  mdtO ← putative multidrug efflux pump subunit MdtO
RA 4,313,171 C→T intergenic (‑180/‑179) alsR ← / → rpiB DNA‑binding transcriptional repressor AlsR/allose‑6‑phosphate isomerase/ribose‑5‑phosphate isomerase B
RA 4,325,644 C→T S33N (AGC→AAC)  yjdN ← PF06983 family protein YjdN
RA 4,358,109 A→G F170S (TTC→TCC)  cadA ← lysine decarboxylase 1
JC JC 4,365,462 IS150 (–) +3 bp intergenic (‑106/+8) cutA ← / ← dcuA copper binding protein CutA/C4‑dicarboxylate transporter DcuA
JC JC 4,370,658 IS150 (+) +3 bp intergenic (‑246/‑28) yjeH ← / → groS L‑methionine/branched chain amino acid exporter/cochaperonin GroES
JC JC 4,385,870 IS2 (–) +5 bp coding (167‑171/315 nt) yjeO → DUF2645 domain‑containing inner membrane protein YjeO
RA 4,392,997 G→A V357V (GTC→GTT queG ← epoxyqueuosine reductase
RA 4,393,552 G→A F172F (TTC→TTT queG ← epoxyqueuosine reductase
RA 4,396,373 C→T T103T (ACC→ACT amiB → N‑acetylmuramoyl‑L‑alanine amidase B
RA 4,396,772 T→C F236F (TTT→TTC amiB → N‑acetylmuramoyl‑L‑alanine amidase B
RA 4,399,936 G→A E229K (GAA→AAA)  miaA → tRNA dimethylallyltransferase
RA 4,423,829 G→A G44S (GGC→AGC)  ulaF → L‑ribulose‑5‑phosphate 4‑epimerase UlaF
RA 4,425,688 C→A H57N (CAC→AAC)  priB → primosomal replication protein N
RA 4,425,696 C→A N59K (AAC→AAA priB → primosomal replication protein N
JC JC 4,430,711 IS150 (–) +3 bp coding (848‑850/1413 nt) cycA → D‑serine/alanine/glycine/:H(+)symporter
RA 4,447,294 G→A G1061G (GGG→GGA tamB → translocation and assembly module subunit TamB
RA 4,460,950 C→T G571S (GGT→AGT)  nrdD ← anaerobic ribonucleoside‑triphosphate reductase
RA 4,465,585 G→A S199F (TCT→TTT)  treB ← trehalose‑specific PTS enzyme IIBC component
RA 4,473,900 C→T G52R (GGA→AGA)  bdcA ← c‑di‑GMP‑binding biofilm dispersal mediator protein
RA 4,475,255 T→C C132R (TGC→CGC)  tabA → DUF386 domain‑containing toxin‑antitoxin biofilm protein TabA
RA 4,475,493 T→C F19F (TTT→TTC yjgL → protein YjgL
RA 4,481,826 G→A S671L (TCG→TTG)  valS ← valine‑‑tRNA ligase
RA 4,486,098 G→A *19* (TGA→TAA)  ytgB → protein YtgB
RA 4,488,217 G→A L300L (CTG→CTA lptG → lipopolysaccharide transport system protein LptG
RA 4,496,431 A→G noncoding (27/85 nt) leuX → tRNA‑Leu
RA 4,496,440 A→T noncoding (36/85 nt) leuX → tRNA‑Leu
RA 4,498,003 G→A intergenic (+1514/‑269) leuX → / → insC6 tRNA‑Leu/IS2 insertion element repressor InsA
RA 4,510,238 T→G intergenic (+445/+452) insO → / ← fecE IS911B regulator fragment/ferric citrate ABC transporter ATP binding subunit
RA 4,512,541 C→T G290E (GGG→GAG)  fecC ← ferric citrate ABC transporter membrane subunit FecC
RA 4,512,767 C→T A215T (GCG→ACG)  fecC ← ferric citrate ABC transporter membrane subunit FecC
RA 4,523,244 C→T G284D (GGC→GAC)  yjhG ← D‑xylonate dehydratase
RA 4,525,237 G→A A189A (GCC→GCT yjhI ← putative DNA‑binding transcriptional regulator YjhI
RA 4,531,425 C→T R76H (CGC→CAC)  sgcX ← putative endoglucanase with Zn‑dependent exopeptidase domain
RA 4,532,409 T→G intergenic (‑758/+28) sgcX ← / ← yjhP putative endoglucanase with Zn‑dependent exopeptidase domain/putative methyltransferase YjhP
RA 4,536,062 G→A intergenic (‑2009/‑535) topAI ← / → ythB toxin of the TopAI‑YjhQ toxin‑antitoxin system, TopA inhibitor/protein YthB
RA 4,536,716 C→T W293* (TGG→TGA nanS ← N‑acetyl‑9‑O‑acetylneuraminate esterase
JC JC 4,542,448 IS5 (–) +4 bp coding (412‑415/597 nt) fimE → regulator for fimA
RA 4,546,601 C→T I502I (ATC→ATT fimD → type I fimbriae usher protein
RA 4,553,339 C→T L147L (CTG→TTG)  uxuB → D‑mannonate oxidoreductase
RA 4,560,446 C→T G79S (GGC→AGC)  yjiH ← uncharacterized protein YjiH
RA 4,571,116 C→T E153E (GAG→GAA yjiR ← fused putative DNA‑binding transcriptional regulator/putative aminotransferase YjiR
RA 4,577,627 C→T S111N (AGC→AAC)  mcrC ← Type IV methyl‑directed restriction enzyme EcoKMcrBC subunit
RA 4,578,534 C→T E268E (GAG→GAA
E268E (GAG→GAA
mcrB ←
mcrB ←
5‑methylcytosine‑specific restriction enzyme subunit McrB
5‑methylcytosine‑specific restriction enzyme subunit McrB
RA 4,584,958 C→T A602T (GCC→ACC)  hsdR ← type I restriction enzyme EcoKI endonuclease subunit
RA 4,589,433 C→T G616D (GGC→GAC)  btsT ← pyruvate:H(+) symporter
RA 4,593,756 C→T G323R (GGG→AGG)  lgoT ← galactonate:H(+) symporter
RA 4,599,184 C→T G86G (GGG→GGA opgB ← phosphoglycerol transferase I
RA 4,609,336 (C)7→8 intergenic (+13/‑78) yjjG → / → prfC pyrimidine 5'‑nucleotidase YjjG/peptide chain release factor RF3
RA 4,611,061 C→T intergenic (+58/‑335) prfC → / → osmY peptide chain release factor RF3/periplasmic chaperone OsmY
RA 4,614,387 C→T intergenic (+127/+293) yjjV → / ← yjjW putative metal‑dependent hydrolase YjjV/putative glycyl‑radical enzyme activating enzyme YjjW
RA 4,614,722 C→T V274V (GTG→GTA yjjW ← putative glycyl‑radical enzyme activating enzyme YjjW
RA 4,632,342 C→T S537F (TCT→TTT)  slt → soluble lytic murein transglycosylase
RA 4,636,541 C→T L179L (CTG→TTG)  creB → DNA‑binding transcriptional regulator CreB
RA 4,636,925 G→C R77P (CGC→CCC)  creC → sensory histidine kinase CreC
RA 4,638,240 G→A L21L (TTG→TTA creD → putative inner membrane protein CreD

Unassigned missing coverage evidence
   seq id start end size ←reads reads→ gene description
* * ÷ NC_000913 257823 258675–257909 87–853 125 [0] [0] 81 crl–insA9 crl,insB9,insA9
* * ÷ NC_000913 1196292 1211446 15155 25 [24] [24] 25 [icd]–mcrA [icd],C0293,ymfD,ymfE,lit,intE,xisE,ymfH,ymfI,ymfJ,ymfK,ymfT,ymfL,ymfM,ymfN,ymfR,beeE,ymfQ,ycfK,tfaP,tfaE,pinE,mcrA
* * ÷ NC_000913 1492145 1492210 66 63 [0] [0] 94 [sokB] [sokB]
* * ÷ NC_000913 1978495 1979270 776 85 [0] [0] 125 insB5–insA5 insB5,insA5
* * ÷ NC_000913 2170380–2171427 2175000 3574–4621 26 [22] [0] 84 [insE5]–[gatA] [insE5],insF5,gatR,gatD,gatB,[gatA]
* * ÷ NC_000913 2755537 2755747 211 26 [23] [24] 26 [ssrA] [ssrA]
* * ÷ NC_000913 3223868 3262483 38616 93 [0] [0] 110 [ebgA]–[tdcD] [ebgA],ebgC,ygjI,ygjJ,ygjK,fadH,higA,higB,rlmG,ygjP,ygjQ,ygjR,alx,sstT,ygjV,uxaA,uxaC,exuT,exuR,yqiM,yqjA,mzrA,yqjC,yqjD,yqjE,yqjK,yqjF,yqjG,yhaH,yhaI,yhaJ,yhaK,yhaL,cyuA,cyuP,tdcG,tdcF,tdcE,[tdcD]
* * ÷ NC_000913 3423829–3424235 3424482–3424239 5–654 25 [24] [23] 25 [rrlD] [rrlD]
* * ÷ NC_000913 4035370–4036866 4036866 1–1497 26 [24] [23] 26 [rrsA] [rrsA]

Unassigned new junction evidence
  seq id position reads (cov) reads (cov) score skew freq annotation gene product
* ? NC_000913 = 2578220 (0.000)124 (1.390) 82/598 0.0 100% intergenic (+51/‑7) frsA/crl fermentation‑respiration switch protein/RNA polymerase holoenzyme assembly factor Crl
?NC_000913 = 382590 NA (NA)noncoding (1331/1331 nt) IS2 repeat region
* ? NC_000913 258676 =0 (0.000)47 (0.720)
+81 bp
40/436 0.3 100% pseudogene (1/331 nt) crl RNA polymerase holoenzyme assembly factor Crl
?NC_000913 = 1469241 NA (NA)intergenic (‑92/‑5) insC2/ydbA IS2 insertion element repressor InsA/putative outer membrane protein, N‑terminal fragment
* ? NC_000913 = 1397238NA (NA)85 (0.950) 58/598 0.3 100% noncoding (1195/1195 nt) IS5 repeat region
?NC_000913 = 1978494 0 (0.000)intergenic (‑297/+24) flhD/insB5 DNA‑binding transcriptional dual regulator FlhD/IS1 family protein InsB
* ? NC_000913 = 14921440 (0.000)63 (0.710) 44/592 0.7 100% noncoding (26/57 nt) sokB putative small regulatory RNA antitoxin SokB
?NC_000913 = 3722075 NA (NA)noncoding (1443/1443 nt) IS150 repeat region
* ? NC_000913 1492211 =0 (0.000)94 (1.060) 62/594 0.2 100% intergenic (+36/‑259) sokB/trg putative small regulatory RNA antitoxin SokB/methyl‑accepting chemotaxis protein Trg
?NC_000913 3720633 = NA (NA)noncoding (1/1443 nt) IS150 repeat region
* ? NC_000913 1979271 =0 (0.000)125 (1.400) 89/598 0.0 100% intergenic (‑56/‑482) insA5/uspC IS1 family protein InsA/universal stress protein C
?NC_000913 = 2102947 NA (NA)pseudogene (443/446 nt) wbbL interrupted rhamnosyltransferase WbbL
* ? NC_000913 = 2170611NA (NA)84 (0.950) 61/594 0.2 100% noncoding (441/1258 nt) IS3 repeat region
?NC_000913 2175001 = 0 (0.000)coding (49/453 nt) gatA galactitol‑specific PTS enzyme IIA component
* ? NC_000913 2288919 =NA (NA)110 (1.240) 76/596 0.1 100% noncoding (1195/1195 nt) IS5 repeat region
?NC_000913 3262484 = 0 (0.000)coding (1177/1209 nt) tdcD propionate kinase
* ? NC_000913 3130146 =NA (NA)93 (1.040) 65/598 0.1 100% noncoding (1/1195 nt) IS5 repeat region
?NC_000913 = 3223867 0 (0.000)coding (1235/3093 nt) ebgA evolved beta‑D‑galactosidase subunit alpha
* ? NC_000913 4542682 =99 (1.110)37 (0.430) 33/580 1.3 26.1% intergenic (+49/‑433) fimE/fimA regulator for fimA/type 1 fimbriae major subunit
?NC_000913 4542996 = 114 (1.320)intergenic (+363/‑119) fimE/fimA regulator for fimA/type 1 fimbriae major subunit