breseq  version 0.39.0  
mutation predictions | marginal predictions | summary statistics | genome diff | command line log

Predicted mutations
evidence position mutation annotation gene description
RA 4,337 C→T L202L (CTG→TTG)  thrC → threonine synthase
RA 10,451 A→G M15T (ATG→ACG)  satP ← acetate/succinate:H(+) symporter
RA 34,388 T→G I30S (ATC→AGC)  caiF → DNA‑binding transcriptional activator CaiF
RA 71,686 C→T T112T (ACC→ACT yabI → DedA family protein YabI
RA 209,056 C→T L146L (CTG→TTG)  accA → acetyl‑CoA carboxyltransferase subunit alpha
RA 246,601 C→T intergenic (‑99/‑111) dinJ ← / → yafL antitoxin/DNA‑binding transcriptional repressor DinJ/NlpC/P60 family protein YafL
JC JC 253,485 IS3 (–) +3 bp intergenic (+324/+772) yafP → / ← pepD putative N‑acetyltransferase YafP/peptidase D
RA 355,714 C→T L265L (CTG→TTG)  codB → cytosine transporter
RA 527,853 G→A E91E (GAG→GAA ybbC → PF15631 family protein YbbC
RA 530,993 C→T Q78Q (CAG→CAA selU ← tRNA 2‑selenouridine synthase
RA 536,841 G→A G86S (GGC→AGC)  glxR → tartronate semialdehyde reductase 2
RA 554,191 G→A L83L (CTG→TTG)  ppiB ← peptidyl‑prolyl cis‑trans isomerase B
RA 557,635 A→T L36Q (CTG→CAG)  folD ← bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
RA 557,785 C→T intergenic (‑44/‑427) folD ← / → sfmA bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/putative fimbrial protein SfmA
RA 558,615 G→A G135E (GGG→GAG)  sfmA → putative fimbrial protein SfmA
RA 561,012 C→T A439V (GCC→GTC)  sfmD → putative fimbrial usher protein SfmD
RA 562,252 G→A Q852Q (CAG→CAA sfmD → putative fimbrial usher protein SfmD
RA 569,047 G→A G49E (GGA→GAA)  ybcK → putative recombinase YbcK
JC JC 572,138 IS2 (+) +5 bp coding (685‑689/798 nt) ybcM → putative DNA‑binding transcriptional regulator
RA 586,190 G→A P240L (CCG→CTG)  envY ← DNA‑binding transcriptional activator EnvY
RA 591,016 C→T M721I (ATG→ATA nfrB ← cyclic di‑3',5'‑guanylate‑activated glycosyltransferase
RA 592,144 G→A T345T (ACC→ACT nfrB ← cyclic di‑3',5'‑guanylate‑activated glycosyltransferase
RA 592,157 G→A T341I (ACC→ATC)  nfrB ← cyclic di‑3',5'‑guanylate‑activated glycosyltransferase
RA 592,507 C→T P224P (CCG→CCA nfrB ← cyclic di‑3',5'‑guanylate‑activated glycosyltransferase
RA 592,824 C→T E119K (GAA→AAA)  nfrB ← cyclic di‑3',5'‑guanylate‑activated glycosyltransferase
RA 596,355 G→A L252L (CTG→CTA cusC → copper/silver export system outer membrane channel
RA 597,771 C→T T98I (ACC→ATC)  cusB → copper/silver export system membrane fusion protein
RA 598,874 C→T P54L (CCC→CTC)  cusA → copper/silver export system RND permease
RA 610,370 C→T G709S (GGT→AGT)  fepA ← ferric enterobactin outer membrane transporter
RA 615,974 C→T S606S (TCC→TCT entF → apo‑serine activating enzyme
RA 617,521 C→T T1122M (ACG→ATG)  entF → apo‑serine activating enzyme
RA 621,495 C→T S232N (AGT→AAT)  fepD ← ferric enterobactin ABC transporter membrane subunit FebD
RA 623,283 C→T S328S (AGC→AGT entS → enterobactin exporter EntS
RA 623,853 C→T E220K (GAA→AAA)  fepB ← ferric enterobactin ABC transporter periplasmic binding protein
RA 623,856 G→A L219L (CTG→TTG)  fepB ← ferric enterobactin ABC transporter periplasmic binding protein
RA 624,165 G→A P116S (CCG→TCG)  fepB ← ferric enterobactin ABC transporter periplasmic binding protein
RA 624,431 G→A A27V (GCT→GTT)  fepB ← ferric enterobactin ABC transporter periplasmic binding protein
RA 625,685 G→A Q267Q (CAG→CAA entC → isochorismate synthase EntC
RA 629,942 G→A G17R (GGA→AGA)  cstA → pyruvate transporter CstA
RA 633,614 G→A S10N (AGC→AAC)  ybdL → methionine transaminase
RA 635,555 C→T G339S (GGC→AGC)  ybdN ← putative PAPS reductase/DUF3440 domain‑containing protein YbdN
RA 635,740 C→T G277E (GGG→GAG)  ybdN ← putative PAPS reductase/DUF3440 domain‑containing protein YbdN
RA 639,552 C→T intergenic (+44/‑201) ahpC → / → ahpF alkyl hydroperoxide reductase, AhpC component/alkyl hydroperoxide reductase, AhpF component
RA 641,472 G→A R132R (CGC→CGT uspG ← universal stress protein G
RA 641,564 C→T E102K (GAA→AAA)  uspG ← universal stress protein G
RA 642,112 C→T P9S (CCA→TCA)  ybdR → putative Zn(2(+))‑dependent alcohol dehydrogenase YbdR
RA 643,938 G→A D10D (GAC→GAT rnk ← nucleoside diphosphate kinase regulator
RA 653,108 G→A A292T (GCG→ACG)  dpiB → sensor histidine kinase DpiB
RA 663,381 C→T A195T (GCG→ACG)  dacA ← D‑alanyl‑D‑alanine carboxypeptidase DacA
RA 664,146 G→A Q349* (CAA→TAA)  rlpA ← rare lipoprotein RlpA
RA 666,284 G→A F10F (TTC→TTT mrdB ← peptidoglycan glycosyltransferase MrdB
RA 668,005 G→A I71I (ATC→ATT mrdA ← peptidoglycan DD‑transpeptidase MrdA
RA 673,515 G→A S423S (TCC→TCT leuS ← leucine‑‑tRNA ligase
RA 677,073 G→A R121R (CGG→CGA ybeR → DUF1266 domain‑containing protein YbeR
RA 679,166 G→A P81S (CCA→TCA)  ybeT ← Sel1 repeat‑containing protein YbeT
RA 679,612 G→A G35G (GGG→GGA ybeU → DUF1266 domain‑containing protein YbeU
RA 679,786 G→A E93E (GAG→GAA ybeU → DUF1266 domain‑containing protein YbeU
RA 679,889 G→A V128I (GTC→ATC)  ybeU → DUF1266 domain‑containing protein YbeU
RA 680,063 G→A A186T (GCG→ACG)  ybeU → DUF1266 domain‑containing protein YbeU
RA 682,466 G→A P310S (CCG→TCG)  hscC ← chaperone protein HscC
RA 690,998 G→A Q263* (CAG→TAG)  ybeX ← CorC‑HlyC family protein YbeX
RA 693,596 G→A P454S (CCG→TCG)  miaB ← isopentenyl‑adenosine A37 tRNA methylthiolase
RA 695,237 G→A S46N (AGC→AAC)  ubiF → 3‑demethoxyubiquinol 3‑hydroxylase
RA 709,993 C→T D68D (GAC→GAT chiQ → lipoprotein ChiQ
RA 728,943 C→T intergenic (‑122/‑191) kdpF ← / → ybfA K(+) transporting P‑type ATPase subunit KdpF/DUF2517 domain‑containing protein YbfA
RA 739,492 C→T R164R (CGC→CGT ybgA → DUF1722 domain‑containing protein YbgA
RA 750,665 G→A T502I (ACC→ATC)  ybgQ ← putative fimbrial usher protein YbgQ
RA 752,352 C→T L148L (CTG→CTA ybgD ← putative fimbrial protein YbgD
RA 753,201 C→T S423N (AGC→AAC)  gltA ← citrate synthase
RA 757,738 C→T A17V (GCT→GTT)  sdhB → succinate:quinone oxidoreductase, iron‑sulfur cluster binding protein
RA 772,257 C→T A267V (GCT→GTT)  cydA → cytochrome bd‑I subunit 1
RA 772,601 C→T R382C (CGT→TGT)  cydA → cytochrome bd‑I subunit 1
RA 783,578 C→T A138V (GCA→GTA)  pnuC → nicotinamide riboside transporter
RA 784,282 C→T G181D (GGC→GAC)  zitB ← Zn(2(+))/Cd(2(+))/Ni(2(+))/Cu(2(+)) exporter
RA 788,000 C→T A280T (GCT→ACT)  galM ← galactose‑1‑epimerase
RA 792,809 C→T S327N (AGC→AAC)  modF ← ABC family protein ModF
RA 794,396 C→T Q83Q (CAG→CAA modE ← DNA‑binding transcriptional dual regulator ModE
RA 811,190 C→T P270P (CCC→CCT bioF → 8‑amino‑7‑oxononanoate synthase
RA 819,880 C→T intergenic (+133/‑4) moaE → / → ybhL molybdopterin synthase catalytic subunit/Bax1‑I family protein YbhL
JC JC 820,823 IS5 (–) +4 bp coding (31‑34/714 nt) ybhM → Bax1‑I family protein YbhM
RA 821,230 C→T A146A (GCC→GCT ybhM → Bax1‑I family protein YbhM
RA 822,611 C→T V377I (GTT→ATT)  clsB ← cardiolipin synthase B
RA 834,360 C→T L431F (CTC→TTC)  dinG → ATP‑dependent DNA helicase DinG
RA 837,571 A→G intergenic (+9/+94) ybiE → / ← ybiJ protein YbiE/DUF1471 domain‑containing protein YbiJ
RA 876,917 C→T E373E (GAG→GAA rimO ← ribosomal protein S12 methylthiotransferase RimO
RA 896,908 C→T P259S (CCG→TCG)  potH → putrescine ABC transporter membrane subunit PotH
RA 901,976 A→G V92A (GTG→GCG)  artQ ← L‑arginine ABC transporter membrane subunit ArtQ
RA 908,844 C→T E151K (GAA→AAA)  ltaE ← low‑specificity L‑threonine aldolase
RA 923,970 T→C V236A (GTG→GCG)  clpA → ATP‑dependent Clp protease ATP‑binding subunit ClpA
RA 934,253 C→T P344S (CCG→TCG)  ftsK → cell division DNA translocase FtsK
RA 951,823 C→T A578T (GCT→ACT)  pflB ← pyruvate formate‑lyase
RA 962,005 C→T S4F (TCT→TTT)  rpsA → 30S ribosomal subunit protein S1
RA 985,174 C→T G179D (GGC→GAC)  aspC ← aspartate aminotransferase
RA 986,934 C→T A17T (GCA→ACA)  ompF ← outer membrane porin F
RA 1,032,327 C→T T63T (ACC→ACT hyaA → hydrogenase 1 small subunit
RA 1,075,193 C→T K1230K (AAG→AAA putA ← fused DNA‑binding transcriptional repressor/proline dehydrogenase/1‑pyrroline‑5‑carboxylate dehydrogenase PutA
RA 1,076,997 C→T R629H (CGC→CAC)  putA ← fused DNA‑binding transcriptional repressor/proline dehydrogenase/1‑pyrroline‑5‑carboxylate dehydrogenase PutA
RA 1,093,264 C→T A130V (GCA→GTA)  dgcT → putative diguanylate cyclase DgcT
JC JC 1,105,376 IS2 (–) +5 bp intergenic (+83/‑34) csgC → / → ymdA curlin chaperone/uncharacterized protein YmdA
RA 1,196,220 C→T H366H (CAC→CAT icd → isocitrate dehydrogenase
RA 1,196,232 C→T T370T (ACC→ACT icd → isocitrate dehydrogenase
RA 1,196,245 T→C L375M (TTA→CTG)  icd → isocitrate dehydrogenase
RA 1,196,247 A→G L375M (TTA→CTG icd → isocitrate dehydrogenase
RA 1,196,277 C→T N385N (AAC→AAT icd → isocitrate dehydrogenase
RA 1,196,280 G→C A386A (GCG→GCC icd → isocitrate dehydrogenase
RA 1,196,283 A→G K387K (AAA→AAG icd → isocitrate dehydrogenase
RA 1,196,292 C→T T390T (ACC→ACT icd → isocitrate dehydrogenase
RA 1,337,394 A→G S522G (AGC→GGC)  acnA → aconitate hydratase 1
RA 1,346,592 C→T A51T (GCT→ACT)  pdeR ← cyclic di‑GMP phosphodiesterase PdeR
RA 1,351,196 (G)7→8 intergenic (‑157/+211) fabI ← / ← ycjD enoyl‑[acyl‑carrier‑protein] reductase/DUF559 domain‑containing protein YcjD
RA 1,351,299 C→T intergenic (‑260/+108) fabI ← / ← ycjD enoyl‑[acyl‑carrier‑protein] reductase/DUF559 domain‑containing protein YcjD
RA 1,354,806 C→T G222D (GGT→GAT)  sapB ← putrescine ABC exporter membrane subunit SapB
RA 1,361,692 C→T S191S (AGC→AGT puuD → gamma‑glutamyl‑gamma‑aminobutyrate hydrolase
RA 1,365,811 C→T L88L (CTG→TTG)  puuE → 4‑aminobutyrate aminotransferase PuuE
RA 1,366,655 C→T A369V (GCG→GTG)  puuE → 4‑aminobutyrate aminotransferase PuuE
RA 1,379,933 C→T P684S (CCT→TCT)  ycjT → kojibiose phosphorylase
MC JC 1,397,239 Δ10,478 bp IS5‑mediated ynaJ[dgcM] ynaJ, uspE, fnr, ogt, abgT, abgB, abgA, abgR, mcaS, smrA, [dgcM]
RA 1,409,540 G→A L10L (TTG→TTA dbpA → ATP‑dependent RNA helicase DbpA
RA 1,458,524 C→T F87F (TTC→TTT paaG → putative ring 1,2‑epoxyphenylacetyl‑CoA isomerase (oxepin‑CoA forming)
RA 1,458,876 C→T P205S (CCG→TCG)  paaG → putative ring 1,2‑epoxyphenylacetyl‑CoA isomerase (oxepin‑CoA forming)
RA 1,527,897 C→T intergenic (+745/‑2025) yncH → / → ydcD DUF5445 domain‑containing protein YncH/uncharacterized protein YdcD
RA 1,608,785 C→T V80I (GTT→ATT)  yneE ← PF01062 family inner membrane protein YneE
RA 1,613,396 C→T K436K (AAG→AAA sad ← succinate semialdehyde dehydrogenase (NAD(P)(+)) Sad
RA 1,626,369 C→T A338T (GCA→ACA)  dcp ← peptidyl‑dipeptidase Dcp
RA 1,652,331 T→C intergenic (+2346/+397) ydfD → / ← ynfP lysis protein/protein YnfP
RA 1,676,072 C→T A97T (GCG→ACG)  pntB ← pyridine nucleotide transhydrogenase subunit beta
RA 1,695,592 G→A Y160Y (TAC→TAT uidA ← beta‑glucuronidase
RA 1,758,462 C→T L88L (CTG→CTA ldtE ← L,D‑transpeptidase LdtE
RA 1,829,704 T→C T11A (ACG→GCG)  astD ← aldehyde dehydrogenase
RA 1,839,554 C→T L30F (CTT→TTT)  ynjE → molybdopterin synthase sulfurtransferase
RA 1,842,076 C→T P20P (CCG→CCA ynjH ← DUF1496 domain‑containing protein YnjH
RA 1,844,295 C→T G193R (GGA→AGA)  ynjI ← DUF1266 domain‑containing protein YnjI
JC JC 1,859,380 IS5 (+) +4 bp coding (847‑850/1380 nt) ydjK ← putative transporter YdjK
JC JC 1,909,378 IS2 (–) +5 bp coding (718‑722/792 nt) kdgR ← DNA‑binding transcriptional repressor KdgR
RA 1,918,032 A→G S175G (AGC→GGC)  letB → lipophilic envelope spanning tunnel
RA 1,972,728 G→A intergenic (‑37/+108) tar ← / ← cheW methyl‑accepting chemotaxis protein Tar/chemotaxis protein CheW
RA 2,021,095 A→G D3G (GAC→GGC)  fliN → flagellar motor switch protein FliN
RA 2,032,423 G→A V219V (GTC→GTT yedJ ← putative HD superfamily phosphohydrolase YedJ
JC JC 2,034,215 +A :: IS3 (+) +5 bp intergenic (+476/‑1616) rseX → / → hchA small regulatory RNA RseX/protein/nucleic acid deglycase 1
RA 2,041,848 C→T A158A (GCC→GCT zinT → metal‑binding protein ZinT
RA 2,042,111 C→T intergenic (+86/‑257) zinT → / → yodB metal‑binding protein ZinT/putative cytochrome b561 YodB
RA 2,043,522 C→A noncoding (36/90 nt) serU ← tRNA‑Ser
RA 2,064,532 G→A L231L (CTG→TTG)  cobS ← cobalamin 5'‑phosphate synthase
RA 2,173,363 Δ2 bp intergenic (‑490/+918) gatD ← / ← gatB galactitol‑1‑phosphate 5‑dehydrogenase/galactitol‑specific PTS enzyme IIB component
RA 2,190,569 C→T G114G (GGG→GGA yehB ← putative fimbrial usher protein YehB
RA 2,208,438 G→A A158T (GCT→ACT)  yehP → VWA domain‑containing protein YehP
RA 2,208,692 G→A W242* (TGG→TGA yehP → VWA domain‑containing protein YehP
RA 2,218,535 G→A P8L (CCT→CTT)  yehY ← glycine betaine ABC transporter membrane subunit YehY
RA 2,221,620 G→A L124F (CTC→TTC)  bglX ← beta‑D‑glucoside glucohydrolase, periplasmic
RA 2,228,777 G→A intergenic (‑1507/‑205) yohF ← / → yohP putative oxidoreductase YohF/putative membrane protein YohP
RA 2,229,789 G→A A199A (GCC→GCT dusC ← tRNA‑dihydrouridine(16) synthase
RA 2,233,312 C→T T145T (ACC→ACT sanA → DUF218 domain‑containing protein SanA
RA 2,236,930 C→T G275D (GGC→GAC)  mglC ← D‑galactose/methyl‑galactoside ABC transporter membrane subunit
RA 2,237,186 C→T A190T (GCG→ACG)  mglC ← D‑galactose/methyl‑galactoside ABC transporter membrane subunit
RA 2,242,537 C→T G144D (GGC→GAC)  yeiB ← DUF418 domain‑containing protein YeiB
RA 2,275,191 C→T T338I (ACC→ATC)  yejB → putative oligopeptide ABC transporter membrane subunit YejB
RA 2,281,965 C→T A445V (GCC→GTC)  radD → putative DNA repair helicase RadD
RA 2,282,594 C→T F26F (TTC→TTT rplY → 50S ribosomal subunit protein L25
RA 2,292,357 C→T A18A (GCG→GCA ccmH ← holocytochrome c synthase CcmH component
RA 2,295,328 C→T G18E (GGG→GAG)  ccmE ← periplasmic heme chaperone
RA 2,297,523 C→T G41E (GGG→GAG)  ccmA ← cytochrome c maturation protein A
RA 2,299,259 C→T W107* (TGG→TAG)  napH ← ferredoxin‑type protein NapH
RA 2,307,752 C→T T288T (ACG→ACA yojI ← ABC transporter family protein/microcin J25 efflux protein
RA 2,314,449 C→T A321V (GCG→GTG)  rcsD → RcsD phosphotransferase
JC JC 2,317,455 IS2 (–) +5 bp coding (2418‑2422/2850 nt) rcsC ← histidine kinase RcsC
RA 2,328,023 C→T D41N (GAT→AAT)  yfaP ← DUF2135 domain‑containing protein YfaP
RA 2,328,771 C→T A343T (GCG→ACG)  yfaQ ← tandem DUF2300 domain‑containing protein YfaQ
RA 2,334,004 C→T intergenic (‑4207/+332) yfaQ ← / ← yfaT tandem DUF2300 domain‑containing protein YfaQ/DUF1175 domain‑containing protein YfaT
RA 2,342,990 C→T A394T (GCT→ACT)  yfaL ← putative autotransporter adhesin YfaL
RA 2,346,833 C→T P657S (CCG→TCG)  nrdA → ribonucleoside‑diphosphate reductase 1 subunit alpha
RA 2,349,985 G→A L343L (CTG→TTG)  glpQ ← glycerophosphoryl diester phosphodiesterase GlpQ
RA 2,351,419 C→T G319D (GGC→GAC)  glpT ← sn‑glycerol 3‑phosphate:phosphate antiporter
RA 2,356,412 C→T P298S (CCG→TCG)  glpC → anaerobic glycerol‑3‑phosphate dehydrogenase subunit C
RA 2,363,006 C→T G210S (GGC→AGC)  yfaY ← IPR008135 CinA family protein YfaY
RA 2,367,767 C→T L233L (CTA→TTA)  arnC → undecaprenyl‑phosphate 4‑deoxy‑4‑formamido‑L‑arabinose transferase
RA 2,370,513 C→T H166Y (CAT→TAT)  arnD → putative 4‑deoxy‑4‑formamido‑L‑arabinose‑phosphoundecaprenol deformylase ArnD
RA 2,372,068 G→A S387S (TCG→TCA arnT → lipid IVA 4‑amino‑4‑deoxy‑L‑arabinosyltransferase
RA 2,373,773 C→T V411M (GTG→ATG)  menE ← o‑succinylbenzoate‑‑CoA ligase
RA 2,374,600 C→T R135H (CGT→CAT)  menE ← o‑succinylbenzoate‑‑CoA ligase
RA 2,385,564 C→T E53E (GAG→GAA yfbK ← IPR002035/DUF3520 domain‑containing protein YfbK
RA 2,392,932 C→T G37E (GGA→GAA)  nuoM ← NADH:quinone oxidoreductase subunit M
JC JC 2,406,780 IS1 (–) +8 bp intergenic (‑139/‑774) lrhA ← / → alaA DNA‑binding transcriptional dual regulator LrhA/glutamate‑‑pyruvate aminotransferase AlaA
RA 2,420,990 (C)6→5 coding (370/648 nt) yfcG → disulfide bond oxidoreductase YfcG
RA 2,536,722 G→T R172R (CGC→CGA pdxK ← pyridoxine/pyridoxal/pyridoxamine kinase
MC JC 2,558,699 Δ6,790 bp intZ[eutA] intZ, yffL, yffM, yffN, yffO, yffP, yffQ, yffR, yffS, [eutA]
RA 2,734,543 (C)8→9 coding (492/732 nt) yfiH ← purine nucleoside phosphorylase YfiH
RA 2,745,600 A→G Y107H (TAC→CAC)  rimM ← ribosome maturation factor RimM
RA 2,765,794 (C)7→8 intergenic (‑18/‑124) yfjM ← / → rnlA protein YfjM/RNase LS, toxin of the RnlAB toxin‑antitoxin system
RA 2,774,947 G→A G544S (GGT→AGT)  yfjW → uncharacterized protein YfjW
RA 2,797,912 G→A L131L (CTG→CTA ygaP → thiosulfate sulfurtransferase YgaP
RA 2,804,682 G→A intergenic (+221/‑133) nrdF → / → proV ribonucleoside‑diphosphate reductase 2 subunit beta/glycine betaine ABC transporter ATP binding subunit ProV
RA 2,817,187 G→A A106V (GCT→GTT)  yqaB ← fructose‑1‑phosphate phosphatase YqaB
RA 2,821,669 G→A L115L (CTG→TTG)  alaS ← alanine‑‑tRNA ligase/DNA‑binding transcriptional repressor
RA 2,824,069 G→A A93V (GCG→GTG)  pncC ← NMN aminohydrolase
RA 2,826,243 C→T P138S (CCA→TCA)  srlA → sorbitol‑specific PTS enzyme IIC2 component
RA 2,827,232 G→A A281T (GCG→ACG)  srlE → sorbitol‑specific PTS enzyme IIBC1 component
RA 2,841,748 G→A W253* (TGG→TGA ascB → 6‑phospho‑beta‑glucosidase AscB
RA 2,851,748 G→A V250I (GTT→ATT)  hypB → hydrogenase isoenzymes nickel incorporation protein HypB
RA 2,859,252 G→A K720K (AAG→AAA mutS → DNA mismatch repair protein MutS
RA 2,867,455 G→A Q33* (CAG→TAG)  rpoS ← RNA polymerase sigma factor RpoS
RA 2,872,778 G→A L15L (CTA→TTA)  ftsB ← cell division protein FtsB
RA 2,874,910 C→T M170I (ATG→ATA cysN ← sulfate adenylyltransferase subunit 1
RA 2,879,750 G→A P8L (CCC→CTC)  cas1 ← multifunctional nuclease Cas1
RA 2,888,425 G→A R559C (CGC→TGC)  cysI ← sulfite reductase, hemoprotein subunit
RA 2,905,760 C→T A17V (GCC→GTC)  ygcG → TPM domain‑containing protein YgcG
RA 2,907,839 C→T A35T (GCA→ACA)  eno ← enolase
RA 2,917,051 G→A K665K (AAG→AAA barA → sensor histidine kinase BarA
RA 2,929,246 G→A G340S (GGT→AGT)  sdaC → L‑serine:H(+) symporter SdaC
RA 2,934,628 G→A G132S (GGT→AGT)  fucP → L‑fucose:H(+) symporter
RA 2,952,553 G→A P1151S (CCG→TCG)  recB ← exodeoxyribonuclease V subunit RecB
RA 2,959,477 G→A H984H (CAC→CAT recC ← exodeoxyribonuclease V subunit RecC
RA 2,964,473 G→A P228L (CCG→CTG)  thyA ← thymidylate synthase
RA 2,964,510 T→C T216A (ACT→GCT)  thyA ← thymidylate synthase
RA 2,966,593 G→A F614F (TTC→TTT ptsP ← phosphoenolpyruvate‑protein phosphotransferase PtsP
RA 2,967,991 G→A T148T (ACC→ACT ptsP ← phosphoenolpyruvate‑protein phosphotransferase PtsP
RA 2,970,027 G→A W122* (TGG→TGA mutH → DNA mismatch repair protein MutH
RA 2,971,906 G→A A104T (GCG→ACG)  tas → putative NADP(H)‑dependent aldo‑keto reductase Tas
RA 2,973,366 G→A A166V (GCC→GTC)  lplT ← lysophospholipid transporter
RA 2,997,876 G→A intergenic (‑276/+158) insC4 ← / ← ygeQ IS2 insertion element repressor InsA/putative lipoprotein YgeQ
RA 2,999,916 G→A intergenic (‑25/‑429) actS ← / → xdhA amidase activator/putative xanthine dehydrogenase molybdenum‑binding subunit XdhA
RA 3,016,633 G→A D192N (GAT→AAT)  ygfK → putative oxidoreductase, Fe‑S subunit
RA 3,021,725 G→A G137D (GGC→GAC)  xdhD → fused putative xanthine/hypoxanthine oxidase: molybdopterin‑binding subunit and Fe‑S binding subunit
RA 3,023,328 G→A L671L (CTG→CTA xdhD → fused putative xanthine/hypoxanthine oxidase: molybdopterin‑binding subunit and Fe‑S binding subunit
RA 3,024,034 G→A V907I (GTC→ATC)  xdhD → fused putative xanthine/hypoxanthine oxidase: molybdopterin‑binding subunit and Fe‑S binding subunit
RA 3,026,913 G→A G383D (GGC→GAC)  guaD → guanine deaminase
RA 3,028,514 G→A intergenic (+26/+10) ghxQ → / ← ygfS guanine/hypoxanthine transporter GhxQ/putative electron transport protein YgfS
RA 3,033,167 T→C F35L (TTC→CTC)  idi → isopentenyl‑diphosphate Delta‑isomerase
RA 3,034,276 G→A T300I (ACT→ATT)  lysS ← lysine‑‑tRNA ligase
RA 3,035,954 G→A L110L (CTG→TTG)  prfB ← peptide chain release factor RF2
RA 3,041,987 G→A K225K (AAG→AAA ygfZ → folate‑binding protein
RA 3,045,471 G→A A144V (GCC→GTC)  ygfF ← putative oxidoreductase YgfF
RA 3,048,038 C→T C335Y (TGT→TAT)  gcvP ← glycine decarboxylase
RA 3,051,880 G→A F146F (TTC→TTT ubiI ← 2‑octaprenylphenol 6‑hydroxylase
RA 3,053,935 C→T L302L (CTG→CTA pepP ← Xaa‑Pro aminopeptidase
RA 3,055,061 G→A G128G (GGC→GGT ygfB ← PF03695 family protein YgfB
RA 3,056,861 G→A noncoding (11/141 nt) sibC → small regulatory RNA antitoxin SibC
RA 3,112,170 G→A Q294* (CAG→TAG)  yghF ← putative type II secretion system C‑type protein YghF
RA 3,118,103 G→A T337I (ACT→ATT)  yghJ ← putative lipoprotein YghJ
RA 3,119,577 G→A intergenic (‑465/+20) yghJ ← / ← glcA putative lipoprotein YghJ/glycolate/lactate:H(+) symporter GlcA
RA 3,138,638 G→A intergenic (‑116/‑89) gss ← / → yghU fused glutathionylspermidine amidase/glutathionylspermidine synthetase/disulfide reductase/organic hydroperoxide reductase
RA 3,145,482 G→A H260H (CAC→CAT hybO ← hydrogenase 2 small subunit
RA 3,146,117 G→A P49S (CCG→TCG)  hybO ← hydrogenase 2 small subunit
RA 3,150,576 G→A intergenic (+30/+242) yghA → / ← exbD NADP(+)‑dependent aldehyde reductase/Ton complex subunit ExbD
RA 3,159,272 G→A S625S (AGC→AGT ygiQ ← radical SAM superfamily protein YgiQ
RA 3,175,417 G→A intergenic (‑21/+8) parE ← / ← yqiA DNA topoisomerase IV subunit B/esterase YqiA
RA 3,177,540 G→A T124I (ACC→ATC)  nudF ← ADP‑sugar pyrophosphatase
RA 3,180,577 G→A A53T (GCC→ACC)  ygiC → putative acid‑‑amine ligase YgiC
RA 3,183,715 G→A intergenic (‑164/+98) yqiD ← / ← ribB protein YqiD/3,4‑dihydroxy‑2‑butanone‑4‑phosphate synthase
RA 3,184,844 T→C I2T (ATT→ACT)  ubiK → ubiquinone biosynthesis accessory factor UbiK
RA 3,184,851 G→A P4P (CCG→CCA ubiK → ubiquinone biosynthesis accessory factor UbiK
RA 3,188,878 G→A pseudogene (1447/2434 nt) yqiG → putative outer membrane usher protein YqiG
RA 3,194,705 G→A intergenic (+180/+16) yqiK → / ← sibD flotillin family inner membrane protein YqiK/small RNA SibD
RA 3,195,045 G→A intergenic (‑180/+52) sibD ← / ← sibE small RNA SibD/small RNA SibE
RA 3,198,889 G→A R251R (CGC→CGT glnE ← fused glutamine synthetase deadenylase/glutamine synthetase adenylyltransferase
RA 3,216,118 G→A T125M (ACG→ATG)  nfeF ← NADPH‑dependent ferric‑chelate reductase
RA 3,220,549 G→A E352E (GAG→GAA patA → putrescine aminotransferase
RA 3,224,264 G→A E544E (GAG→GAA ebgA → evolved beta‑D‑galactosidase subunit alpha
RA 3,228,128 G→A D110N (GAC→AAC)  ygjJ → protein YgjJ
RA 3,231,109 G→A G741E (GGG→GAG)  ygjK → glycoside hydrolase
RA 3,232,391 G→A A243T (GCG→ACG)  fadH → 2,4‑dienoyl‑CoA reductase
RA 3,233,924 G→A A74V (GCT→GTT)  higA ← antitoxin/DNA‑binding transcriptional repressor HigA
RA 3,239,888 G→A intergenic (+343/‑56) alx → / → sstT putative membrane‑bound redox modulator Alx/serine/threonine:Na(+) symporter
RA 3,242,141 G→A P392S (CCG→TCG)  uxaA ← D‑altronate dehydratase
RA 3,246,567 G→A intergenic (+45/‑85) exuT → / → exuR hexuronate transporter/DNA‑binding transcriptional repressor ExuR
RA 3,253,554 G→A P221S (CCG→TCG)  yhaJ ← DNA‑binding transcriptional activator YhaJ
RA 3,263,021 G→A R214C (CGC→TGC)  tdcD ← propionate kinase
RA 3,263,139 G→A F174F (TTC→TTT tdcD ← propionate kinase
RA 3,273,352 G→A A69V (GCC→GTC)  garL ← alpha‑dehydro‑beta‑deoxy‑D‑glucarate aldolase
RA 3,291,032 G→A R740K (AGA→AAA)  yraJ → putative fimbrial usher protein YraJ
RA 3,291,034 G→A G741S (GGT→AGT)  yraJ → putative fimbrial usher protein YraJ
RA 3,292,564 G→A P258S (CCG→TCG)  rsmI ← 16S rRNA 2'‑O‑ribose C1402 methyltransferase
RA 3,295,957 G→A G50E (GGA→GAA)  diaA → DnaA initiator‑associating protein DiaA
RA 3,297,101 G→A F346F (TTC→TTT yraQ ← permease family protein YraQ
RA 3,309,827 G→A L448L (CTG→TTG)  pnp ← polynucleotide phosphorylase
RA 3,310,086 G→A D361D (GAC→GAT pnp ← polynucleotide phosphorylase
RA 3,314,178 G→A L613L (CTG→TTG) 
L613L (CTG→TTG) 
L613L (CTG→TTG) 
infB ←
infB ←
infB ←
translation initiation factor IF‑2beta'
translation initiation factor IF‑2beta'
translation initiation factor IF‑2beta'
RA 3,318,266 G→A noncoding (24/77 nt) metY ← tRNA‑Met
RA 3,318,695 G→A G20D (GGC→GAC)  argG → argininosuccinate synthetase
RA 3,322,917 G→A P385L (CCA→CTA)  glmM ← phosphoglucosamine mutase
RA 3,330,184 G→A A408T (GCG→ACG)  dacB → peptidoglycan DD‑endopeptidase DacB
RA 3,333,778 G→A E23E (GAG→GAA ispB → all‑trans‑octaprenyl‑diphosphate synthase
RA 3,340,605 G→A V111I (GTC→ATC)  yrbG → putative transport protein YrbG
RA 3,340,850 G→A M192I (ATG→ATA yrbG → putative transport protein YrbG
RA 3,346,959 G→A A128T (GCG→ACG)  ptsN → phosphotransferase system enzyme IIA(Ntr)
RA 3,349,687 G→A F41F (TTC→TTT mtgA ← peptidoglycan glycosyltransferase MtgA
RA 3,353,339 G→A L238L (CTG→TTG)  yhcC ← radical SAM family oxidoreductase YhcC
RA 3,357,688 G→A K988K (AAG→AAA gltB → glutamate synthase subunit GltB
RA 3,359,233 G→A Q12Q (CAG→CAA gltD → glutamate synthase subunit GltD
RA 3,361,773 G→A E200K (GAG→AAG)  gltF → periplasmic protein GltF
RA 3,362,046 G→A intergenic (+106/‑66) gltF → / → yhcA periplasmic protein GltF/putative fimbrial chaperone YhcA
RA 3,362,537 G→A W142* (TGG→TGA yhcA → putative fimbrial chaperone YhcA
RA 3,367,830 G→A E2K (GAA→AAA)  yhcG → DUF1016 domain‑containing protein YhcG
RA 3,368,713 G→A G296E (GGA→GAA)  yhcG → DUF1016 domain‑containing protein YhcG
RA 3,371,094 G→A T494I (ACC→ATC)  nanT ← N‑acetylneuraminate:H(+) symporter
RA 3,373,424 G→A A51A (GCC→GCT nanA ← N‑acetylneuraminate lyase
RA 3,373,503 G→A A25V (GCG→GTG)  nanA ← N‑acetylneuraminate lyase
RA 3,376,928 G→A L165L (CTG→TTG)  sspA ← stringent starvation protein A
RA 3,379,523 G→A L159L (CTG→TTG)  zapE ← cell division protein ZapE
RA 3,379,739 G→A L87L (CTG→TTG)  zapE ← cell division protein ZapE
RA 3,382,823 G→A S208S (TCG→TCA degS → serine endoprotease
RA 3,385,201 G→A intergenic (+28/‑337) argR → / → yhcN DNA‑binding transcriptional dual regulator ArgR/DUF1471 domain‑containing stress‑induced protein YhcN
RA 3,385,643 G→A A36T (GCA→ACA)  yhcN → DUF1471 domain‑containing stress‑induced protein YhcN
RA 3,391,313 G→A S239F (TCT→TTT)  tldD ← metalloprotease subunit TldD
RA 3,392,341 G→A intergenic (‑313/+117) tldD ← / ← yhdP metalloprotease subunit TldD/phospholipid transport factor YhdP
RA 3,392,436 G→A intergenic (‑408/+22) tldD ← / ← yhdP metalloprotease subunit TldD/phospholipid transport factor YhdP
RA 3,394,608 G→A P551S (CCC→TCC)  yhdP ← phospholipid transport factor YhdP
RA 3,395,443 G→A G272G (GGC→GGT yhdP ← phospholipid transport factor YhdP
RA 3,395,871 G→A L130L (CTG→TTG)  yhdP ← phospholipid transport factor YhdP
RA 3,397,079 G→A Y239Y (TAC→TAT rng ← RNase G
RA 3,407,078 C→T L388L (CTG→TTG)  accC → biotin carboxylase
RA 3,412,497 G→A S282N (AGC→AAC)  yhdJ → DNA adenine methyltransferase
RA 3,418,812 G→A intergenic (+201/‑1322) yhdV → / → yhdX lipoprotein YhdV/putative ABC transporter membrane subunit YhdX
RA 3,436,981 T→C L155P (CTG→CCG)  trkA → NAD‑binding component of Trk potassium transporters
RA 3,455,511 G→A intergenic (‑113/‑67) gspA ← / → gspC Type II secretion system protein GspA/Type II secretion system protein GspC
RA 3,486,205 C→A T29K (ACG→AAG)  crp → DNA‑binding transcriptional dual regulator CRP
RA 3,493,996 G→A intergenic (+247/‑15) tsgA → / → nirB putative transporter TsgA/nitrite reductase (NADH) large subunit
RA 3,542,162 G→A G586S (GGT→AGT)  feoB → Fe(2(+)) transporter FeoB
RA 3,560,455 +G intergenic (+589/+167) rtcR → / ← glpG DNA‑binding transcriptional activator RtcR/rhomboid protease GlpG
RA 3,578,904 G→A intergenic (‑178/+46) gntR ← / ← yhhW DNA‑binding transcriptional repressor GntR/quercetin 2,3‑dioxygenase
RA 3,579,793 G→A P338L (CCC→CTC)  yhhX ← putative oxidoreductase YhhX
RA 3,585,815 G→A R337C (CGC→TGC)  ggt ← glutathione hydrolase proenzyme
RA 3,594,263 C→T L406L (CTG→CTA livM ← branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM
RA 3,595,132 G→A L117L (CTG→TTG)  livM ← branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM
RA 3,596,871 C→T G230G (GGG→GGA livK ← L‑leucine/L‑phenylalanine ABC transporter periplasmic binding protein
RA 3,598,338 G→A A119T (GCA→ACA)  panZ → PanD maturation factor
RA 3,605,679 C→T intergenic (‑69/‑72) yhhM ← / → yhhN DUF2500 domain‑containing protein YhhM/PF07947 family protein YhhN
RA 3,605,956 C→T T69I (ACC→ATC)  yhhN → PF07947 family protein YhhN
RA 3,611,416 G→A T106T (ACC→ACT yhhS ← putative transporter YhhS
RA 3,611,718 C→T A6T (GCC→ACC)  yhhS ← putative transporter YhhS
RA 3,613,896 C→T T77I (ACT→ATT)  nikA → Ni(2(+)) ABC transporter periplasmic binding protein
RA 3,614,465 C→T P267S (CCG→TCG)  nikA → Ni(2(+)) ABC transporter periplasmic binding protein
RA 3,614,601 C→T A312V (GCC→GTC)  nikA → Ni(2(+)) ABC transporter periplasmic binding protein
RA 3,617,900 C→T A42V (GCC→GTC)  nikE → Ni(2(+)) ABC transporter ATP binding subunit NikE
RA 3,618,167 C→T A131V (GCC→GTC)  nikE → Ni(2(+)) ABC transporter ATP binding subunit NikE
RA 3,625,578 G→A intergenic (+64/+101) yhhI → / ← yhhJ putative transposase/ABC transporter family protein YhhJ
RA 3,626,914 G→A F875F (TTC→TTT rbbA ← ribosome‑associated ATPase
RA 3,628,144 G→A T465T (ACC→ACT rbbA ← ribosome‑associated ATPase
RA 3,631,311 C→T S427N (AGC→AAC)  yhiJ ← DUF4049 domain‑containing protein YhiJ
RA 3,633,214 G→A intergenic (‑624/‑1627) yhiJ ← / → yhiM DUF4049 domain‑containing protein YhiJ/inner membrane protein YhiM
RA 3,634,197 G→A intergenic (‑1607/‑644) yhiJ ← / → yhiM DUF4049 domain‑containing protein YhiJ/inner membrane protein YhiM
RA 3,634,570 G→A intergenic (‑1980/‑271) yhiJ ← / → yhiM DUF4049 domain‑containing protein YhiJ/inner membrane protein YhiM
RA 3,640,390 G→A V94I (GTT→ATT)  uspA → universal stress protein A
RA 3,644,337 G→A S282S (TCC→TCT prlC ← oligopeptidase A
RA 3,646,995 G→A A233T (GCG→ACG)  gor → glutathione reductase (NADPH)
RA 3,648,930 G→A intergenic (+49/‑5) arsR → / → arsB DNA‑binding transcriptional repressor ArsR/arsenite/antimonite:H(+) antiporter
RA 3,651,716 G→A pseudogene (426/746 nt) yhiS → putative uncharacterized protein YhiS
RA 3,658,173 G→A intergenic (‑119/‑193) arrS ← / → gadE small regulatory RNA ArrS/DNA‑binding transcriptional activator GadE
RA 3,659,541 G→A A104T (GCC→ACC)  mdtE → multidrug efflux pump membrane fusion protein MdtE
RA 3,665,210 G→A L201F (CTT→TTT)  gadX ← DNA‑binding transcriptional dual regulator GadX
RA 3,675,932 G→A A383T (GCA→ACA)  yhjE → putative transporter YhjE
RA 3,677,097 G→A R418R (CGC→CGT yhjG ← AsmA family protein YhjG
RA 3,677,227 C→T G375E (GGG→GAG)  yhjG ← AsmA family protein YhjG
RA 3,679,077 G→A I37I (ATC→ATT pdeH ← c‑di‑GMP phosphodiesterase PdeH
RA 3,685,523 G→A F32F (TTC→TTT pdeK ← c‑di‑GMP phosphodiesterase PdeK
RA 3,695,147 C→T S30S (TCG→TCA bcsA ← cellulose synthase catalytic subunit
RA 3,700,639 G→A C26Y (TGC→TAC)  yhjV → putative transporter YhjV
RA 3,701,327 G→A V255V (GTG→GTA yhjV → putative transporter YhjV
RA 3,704,085 C→T G226D (GGT→GAT)  dppC ← dipeptide ABC transporter membrane subunit DppC
RA 3,718,924 G→A L41L (CTG→TTG)  yiaF ← DUF3053 domain‑containing protein YiaF
RA 3,719,664 G→A V63I (GTA→ATA)  yiaG → putative DNA‑binding transcriptional regulator YiaG
RA 3,719,756 G→A Q93Q (CAG→CAA yiaG → putative DNA‑binding transcriptional regulator YiaG
RA 3,734,743 G→A G342R (GGA→AGA)  xylH → xylose ABC transporter membrane subunit
RA 3,747,664 G→A C194Y (TGC→TAC)  lyxK → L‑xylulose kinase
RA 3,749,611 G→A G127D (GGC→GAC)  sgbU → putative L‑xylulose 5‑phosphate 3‑epimerase
RA 3,770,266 G→A H372Y (CAT→TAT)  yibH ← inner membrane protein YibH
RA 3,779,756 G→A D235N (GAT→AAT)  lldR → DNA‑binding transcriptional dual regulator LldR
RA 3,780,632 G→A G269E (GGA→GAA)  lldD → L‑lactate dehydrogenase
RA 3,780,774 G→A V316V (GTG→GTA lldD → L‑lactate dehydrogenase
RA 3,785,193 G→A intergenic (‑178/‑67) yibN ← / → gpmM putative sulfurtransferase YibN/2,3‑bisphosphoglycerate‑independent phosphoglycerate mutase
RA 3,786,558 G→A E433E (GAG→GAA gpmM → 2,3‑bisphosphoglycerate‑independent phosphoglycerate mutase
RA 3,793,506 G→A P60S (CCA→TCA)  htrL ← protein HtrL
RA 3,798,042 T→C Y365Y (TAT→TAC
I36M (ATA→ATG
waaL →
yibY ←
O‑antigen ligase
protein YibY
RA 3,802,282 G→A N259N (AAC→AAT waaO ← UDP‑D‑glucose:(glucosyl)LPS alpha‑1,3‑glucosyltransferase
RA 3,803,543 G→A L199F (CTT→TTT)  waaB ← UDP‑D‑galactose:(glucosyl)lipopolysaccharide‑1, 6‑D‑galactosyltransferase
RA 3,817,038 G→A Q121Q (CAG→CAA yicC → putative RNase adaptor protein YicC
RA 3,838,014 G→A W354* (TGG→TGA setC → putative arabinose exporter
RA 3,841,248 G→A G164G (GGC→GGT nepI ← purine ribonucleoside exporter
RA 3,843,586 G→A T68T (ACC→ACT adeQ ← adenine transporter
RA 3,845,694 G→A E577E (GAG→GAA adeD → adenine deaminase
RA 3,847,169 G→A intergenic (‑2/+136) uhpT ← / ← uhpC hexose‑6‑phosphate:phosphate antiporter/inner membrane protein sensing glucose‑6‑phosphate
RA 3,849,610 G→A S176F (TCT→TTT)  uhpB ← sensory histidine kinase UhpB
MC JC 3,898,712 Δ13 bp coding (670‑682/723 nt) yieK ← putative glucosamine‑6‑phosphate deaminase YieK
RA 3,905,097 G→A F167F (TTC→TTT bglF ← beta‑glucoside specific PTS enzyme II/BglG kinase/BglG phosphatase
RA 3,910,989 T→C E179E (GAA→GAG pstS ← phosphate ABC transporter periplasmic binding protein
RA 3,929,767 G→A P443S (CCT→TCT)  ravA ← regulatory ATPase RavA
RA 3,931,797 G→A G161D (GGC→GAC)  kup → K(+):H(+) symporter Kup
RA 3,935,229 G→A Q484Q (CAG→CAA rbsA → ribose ABC transporter ATP binding subunit
RA 3,937,366 C→T P25S (CCT→TCT)  rbsK → ribokinase
RA 3,948,012 G→T intergenic (‑45/‑74) hdfR ← / → maoP DNA‑binding transcriptional dual regulator HdfR/macrodomain Ori protein
RA 3,962,320 G→A E548E (GAG→GAA rep → ATP‑dependent DNA helicase Rep
RA 3,967,102 C→T A229V (GCT→GTT)  rho → transcription termination factor Rho
RA 3,979,885 C→T L429F (CTT→TTT)  wzyE → enterobacterial common antigen polymerase
RA 3,982,057 G→A A391T (GCG→ACG)  yifK → putative transporter YifK
RA 3,982,233 C→T G449G (GGC→GGT yifK → putative transporter YifK
RA 3,982,684 (C)8→9 noncoding (79/87 nt) leuT → tRNA‑Leu
RA 3,987,625 C→T K86K (AAG→AAA hemY ← protein HemY
RA 3,988,232 G→A L279L (CTG→TTG)  hemX ← PF04375 family protein HemX
RA 3,993,453 G→A E767E (GAG→GAA cyaA → adenylate cyclase
RA 3,993,803 G→A T86I (ACC→ATC)  cyaY ← frataxin CyaY
RA 3,999,198 G→A A406T (GCC→ACC)  uvrD → DNA helicase II
RA 4,003,789 C→T W130* (TGG→TGA rarD ← putative transporter RarD
RA 4,007,155 G→A G431E (GGG→GAG)  recQ → ATP‑dependent DNA helicase RecQ
RA 4,020,978 G→A V251V (GTG→GTA ubiB → ubiquinone biosynthesis protein UbiB
RA 4,021,067 G→A R281H (CGC→CAC)  ubiB → ubiquinone biosynthesis protein UbiB
RA 4,025,224 G→A Q79Q (CAG→CAA ubiD → 3‑octaprenyl‑4‑hydroxybenzoate decarboxylase
RA 4,031,554 G→A V132M (GTG→ATG)  pepQ → Xaa‑Pro dipeptidase
RA 4,033,929 G→A G262E (GGG→GAG)  trkH → K(+) transporter TrkH
RA 4,035,599 G→A noncoding (69/1542 nt) rrsA → 16S ribosomal RNA
RA 4,038,899 G→A noncoding (1381/2905 nt) rrlA → 23S ribosomal RNA
RA 4,039,635 G→A noncoding (2117/2905 nt) rrlA → 23S ribosomal RNA
RA 4,042,171 G→A E35K (GAG→AAG)  yihD → DUF1040 domain‑containing protein YihD
RA 4,046,082 G→A S174F (TCT→TTT)  yihG ← 1‑acylglycerol‑3‑phosphate O‑acyltransferase YihG
RA 4,048,504 G→A W513* (TGG→TGA polA → DNA polymerase I
RA 4,050,592 G→A T58T (ACC→ACT yihA ← GTP‑binding protein YihA
RA 4,063,412 G→A G389D (GGC→GAC)  yihN → putative transporter YihN
RA 4,065,084 G→A S228L (TCA→TTA)  yihO ← putative sulfoquinovose transporter
JC 4,123,824 Δ8 bp coding (626‑633/1026 nt) cytR ← DNA‑binding transcriptional repressor CytR
RA 4,130,929 C→T T365T (ACC→ACT metL → fused aspartate kinase/homoserine dehydrogenase 2
RA 4,157,011 G→A E54E (GAG→GAA argH → argininosuccinate lyase
RA 4,157,435 G→A G196S (GGC→AGC)  argH → argininosuccinate lyase
RA 4,160,102 C→T S230N (AGT→AAT)  sthA ← soluble pyridine nucleotide transhydrogenase
JC 4,180,675 Δ15 bp coding (116‑130/366 nt) rplL → 50S ribosomal subunit protein L12
RA 4,193,113 C→T G155D (GGC→GAC)  thiF ← sulfur carrier protein ThiS adenylyltransferase
RA 4,197,052 G→A Q50Q (CAG→CAA nudC → RNA decapping hydrolase
RA 4,197,479 C→T P193S (CCG→TCG)  nudC → RNA decapping hydrolase
RA 4,197,628 C→T R242R (CGC→CGT nudC → RNA decapping hydrolase
RA 4,199,949 C→T A149V (GCT→GTT)  yjaG → DUF416 domain‑containing protein YjaG
RA 4,200,836 C→T L91F (CTC→TTC)  yjaH → DUF1481 domain‑containing protein YjaH
RA 4,202,268 C→T L115F (CTC→TTC)  zraS → sensor histidine kinase ZraS
RA 4,205,740 C→T K64K (AAG→AAA purD ← phosphoribosylamine‑‑glycine ligase
RA 4,208,302 C→T noncoding (156/1542 nt) rrsE → 16S ribosomal RNA
RA 4,226,531 C→T P902S (CCA→TCA)  metH → cobalamin‑dependent methionine synthase
RA 4,271,791 C→T G694D (GGT→GAT)  uvrA ← UvrABC excision nuclease subunit A
RA 4,287,372 G→T intergenic (‑1/‑239) acs ← / → ytcB acetyl‑CoA synthetase (AMP‑forming)/protein YtcB
RA 4,296,381 +GC intergenic (+587/+55) gltP → / ← yjcO glutamate/aspartate : H(+) symporter GltP/Sel1 repeat‑containing protein YjcO
RA 4,478,030 G→A A94A (GCC→GCT argI ← ornithine carbamoyltransferase ArgI
RA 4,548,969 C→G N54K (AAC→AAG fimH → type 1 fimbriae D‑mannose specific adhesin
RA 4,610,388 T→C Y325Y (TAT→TAC prfC → peptide chain release factor RF3

Unassigned missing coverage evidence
   seq id start end size ←reads reads→ gene description
* * ÷ NC_000913 257886 258675–257909 24–790 118 [0] [0] 77 [crl]–insA9 [crl],insB9,insA9
* * ÷ NC_000913 1196299 1211431 15133 23 [22] [22] 24 [icd]–mcrA [icd],C0293,ymfD,ymfE,lit,intE,xisE,ymfH,ymfI,ymfJ,ymfK,ymfT,ymfL,ymfM,ymfN,ymfR,beeE,ymfQ,ycfK,tfaP,tfaE,pinE,mcrA
* * ÷ NC_000913 1978495 1979270–1978504 10–776 95 [0] [0] 107 insB5–insA5 insB5,insA5
* * ÷ NC_000913 2755533 2755721 189 23 [22] [22] 23 [ssrA] [ssrA]
* * ÷ NC_000913 3423844–3424230 3424446–3424238 9–603 23 [22] [22] 24 [rrlD] [rrlD]

Unassigned new junction evidence
  seq id position reads (cov) reads (cov) score skew freq annotation gene product
* ? NC_000913 = 2578850 (0.000)118 (1.350) 85/598 0.0 100% pseudogene (57/71 nt) crl RNA polymerase holoenzyme assembly factor Crl
?NC_000913 391709 = NA (NA)noncoding (1258/1258 nt) IS3 repeat region
* ? NC_000913 258676 =0 (0.000)70 (0.850)
+CGAATATACGGGCCTAG
54/564 0.3 100% pseudogene (1/331 nt) crl RNA polymerase holoenzyme assembly factor Crl
?NC_000913 = 392966 NA (NA)noncoding (1/1258 nt) IS3 repeat region
* ? NC_000913 391883 =NA (NA)55 (0.630) 42/598 0.8 NA noncoding (1084/1258 nt) IS3 repeat region
?NC_000913 = 392966 NA (NA)noncoding (1/1258 nt) IS3 repeat region
* ? NC_000913 567858 =8 (0.090)80 (0.920) 60/596 0.2 90.9% noncoding (1082/1258 nt) IS3 repeat region
?NC_000913 = 568034 NA (NA)noncoding (1258/1258 nt) IS3 repeat region
* ? NC_000913 = 1397238NA (NA)95 (1.090) 59/598 0.3 100% noncoding (1195/1195 nt) IS5 repeat region
?NC_000913 = 1978494 0 (0.000)intergenic (‑297/+24) flhD/insB5 DNA‑binding transcriptional dual regulator FlhD/IS1 family protein InsB
* ? NC_000913 1979271 =0 (0.000)106 (1.210) 79/598 0.0 100% intergenic (‑56/‑482) insA5/uspC IS1 family protein InsA/universal stress protein C
?NC_000913 = 2102947 NA (NA)pseudogene (443/446 nt) wbbL interrupted rhamnosyltransferase WbbL
* ? NC_000913 3720633 =NA (NA)99 (1.130) 67/598 0.1 NA noncoding (1/1443 nt) IS150 repeat region
?NC_000913 3762460 = NA (NA)coding (278/4134 nt) rhsA rhs element protein RhsA
* ? NC_000913 = 3722075NA (NA)125 (1.430) 68/598 0.1 100% noncoding (1443/1443 nt) IS150 repeat region
?NC_000913 = 3762462 0 (0.000)coding (280/4134 nt) rhsA rhs element protein RhsA