breseq  version 0.39.0  
mutation predictions | marginal predictions | summary statistics | genome diff | command line log

Predicted mutations
evidence position mutation annotation gene description
JC JC 59,123 IS150 (+) +3 bp coding (3‑5/159 nt) yabQ → protein YabQ
RA 85,520 C→T intergenic (‑9/‑110) yabR ← / → ilvI protein YabR/acetolactate synthase/acetohydroxybutanoate synthase, catalytic subunit
RA 92,790 C→T P460S (CCG→TCG)  ftsI → peptidoglycan DD‑transpeptidase FtsI
RA 204,147 C→T A267V (GCC→GTC)  lpxB → lipid A disaccharide synthase
JC JC 214,173 IS2 (–) +5 bp intergenic (‑48/‑114) yaeP ← / → yaeQ PF06786 family protein YaeP/uncharacterized protein YaeQ
RA 229,802 G→A M212I (ATG→ATA dkgB → methylglyoxal reductase DkgB
RA 230,017 G→A L289F (CTT→TTT)  yafC ← DNA‑binding transcriptional regulator YafC
RA 238,884 G→A intergenic (‑148/+535) ykfM ← / ← yafV uncharacterized protein YkfM/2‑oxoglutaramate amidase
RA 239,930 G→A S87F (TCT→TTT)  yafV ← 2‑oxoglutaramate amidase
RA 243,084 G→A R74C (CGC→TGC)  fadE ← acyl‑CoA dehydrogenase
RA 245,766 G→A P14S (CCG→TCG)  dpaA ← peptidoglycan meso‑diaminopimelic acid protein amidase A
RA 246,747 G→T S12S (TCG→TCT yafL → NlpC/P60 family protein YafL
RA 251,604 G→A S236N (AGC→AAC)  dinB → DNA polymerase IV
RA 252,349 G→A E17K (GAA→AAA)  yafO → ribosome‑dependent mRNA interferase toxin YafO
RA 253,835 G→A intergenic (+674/+424) yafP → / ← pepD putative N‑acetyltransferase YafP/peptidase D
RA 266,523 G→A L11L (CTG→TTG)  yafY ← inner membrane lipoprotein YafY
RA 267,149 G→A intergenic (‑596/+35) yafY ← / ← yafZ inner membrane lipoprotein YafY/DUF932 domain‑containing protein YafZ
RA 268,709 G→A R84R (CGC→CGT ykfA ← putative GTP‑binding protein YkfA
RA 273,450 G→A A202T (GCG→ACG)  ykfC → PF00078 domain‑containing protein YkfC
RA 273,734 G→A Q296Q (CAG→CAA ykfC → PF00078 domain‑containing protein YkfC
RA 274,939 G→A A48V (GCT→GTT)  insH1 ← IS5 family transposase and trans‑activator
RA 274,985 G→A P33S (CCA→TCA)  insH1 ← IS5 family transposase and trans‑activator
RA 275,668 G→A G115E (GGA→GAA)  mmuP → S‑methyl‑L‑methionine transporter
RA 277,277 G→A R188H (CGT→CAT)  mmuM → homocysteine S‑methyltransferase
RA 281,053 T→C T311A (ACG→GCG)  yagA ← integrase core domain‑containing protein YagA
RA 281,778 G→A S69F (TCC→TTC)  yagA ← integrase core domain‑containing protein YagA
RA 284,535 T→G A445A (GCT→GCG yagF → D‑xylonate dehydratase
RA 285,966 G→A G191D (GGC→GAC)  yagG → putative D‑xylonate transporter YagG
RA 287,324 G→A G179D (GGC→GAC)  yagH → putative xylosidase/arabinosidase
RA 287,348 G→A G187D (GGC→GAC)  yagH → putative xylosidase/arabinosidase
RA 287,946 G→A W386* (TGG→TGA yagH → putative xylosidase/arabinosidase
RA 288,641 G→A A174A (GCC→GCT xynR ← DNA‑binding transcriptional repressor XynR
RA 294,857 G→A intergenic (‑58/+61) yagM ← / ← ykgV protein YagM/protein YkgV
RA 295,209 G→A T124I (ACT→ATT)  yagN ← protein YagN
RA 298,897 G→A P680S (CCC→TCC)  paoC ← aldehyde dehydrogenase: molybdenum cofactor‑binding subunit
RA 305,439 G→A S460F (TCC→TTC)  ecpD ← fimbrial adhesin EcpD
RA 305,990 G→A I276I (ATC→ATT ecpD ← fimbrial adhesin EcpD
RA 308,924 G→A R137C (CGC→TGC)  ecpC ← putative fimbrial usher protein EcpC
RA 310,789 G→A A183V (GCT→GTT)  matA ← DNA‑binding transcriptional dual regulator MatA
RA 313,543 G→A intergenic (‑301/‑1748) ykgR ← / → insE1 putative membrane protein YkgR/IS3 element protein InsE
RA 314,622 G→A intergenic (‑1380/‑669) ykgR ← / → insE1 putative membrane protein YkgR/IS3 element protein InsE
RA 316,519 G→A intergenic (+66/+1207) insF1 → / ← rclC IS3 element protein InsF/DUF417 domain‑containing inner membrane protein RclC
RA 316,837 G→A intergenic (+384/+889) insF1 → / ← rclC IS3 element protein InsF/DUF417 domain‑containing inner membrane protein RclC
RA 320,300 G→A S25N (AGT→AAT)  rclR → DNA‑binding transcriptional activator RclR
RA 324,926 G→A P147S (CCT→TCT)  ykgH ← uncharacterized protein YkgH
RA 328,598 C→T V46I (GTC→ATC)  betB ← betaine aldehyde dehydrogenase
RA 339,376 G→A G351E (GGG→GAG)  yahG → DUF1116 domain‑containing protein YahG
RA 339,935 C→T A56V (GCC→GTC)  yahH → putative uncharacterized protein YahH
RA 339,941 C→T T58I (ACT→ATT)  yahH → putative uncharacterized protein YahH
RA 339,958 G→A D64N (GAC→AAC)  yahH → putative uncharacterized protein YahH
RA 343,442 G→A G187R (GGA→AGA)  yahK → aldehyde reductase, NADPH‑dependent
RA 343,667 G→A G262S (GGC→AGC)  yahK → aldehyde reductase, NADPH‑dependent
RA 347,833 G→A A204V (GCC→GTC)  prpR ← DNA‑binding transcriptional dual regulator PrpR
RA 352,642 G→A E476E (GAG→GAA prpD → 2‑methylcitrate dehydratase
RA 352,850 G→A G49S (GGC→AGC)  prpE → propionyl‑CoA synthetase
RA 353,100 G→A G132D (GGC→GAC)  prpE → propionyl‑CoA synthetase
RA 355,006 G→A G29R (GGA→AGA)  codB → cytosine transporter
RA 355,064 G→A S48N (AGC→AAC)  codB → cytosine transporter
RA 355,229 G→A G103E (GGA→GAA)  codB → cytosine transporter
RA 356,687 G→A A173T (GCG→ACG)  codA → cytosine/isoguanine deaminase
RA 357,285 G→A G372E (GGA→GAA)  codA → cytosine/isoguanine deaminase
RA 358,368 G→A P108L (CCC→CTC)  cynR ← DNA‑binding transcriptional dual regulator CynR
RA 360,082 G→A G31R (GGA→AGA)  cynX → cyanate transporter
RA 360,137 G→A G49D (GGC→GAC)  cynX → cyanate transporter
RA 360,536 C→T S182F (TCC→TTC)  cynX → cyanate transporter
RA 360,786 G→A M265I (ATG→ATA cynX → cyanate transporter
RA 361,489 G→A N124N (AAC→AAT lacA ← galactoside O‑acetyltransferase
RA 364,433 G→A Q625* (CAG→TAG)  lacZ ← beta‑galactosidase
RA 365,146 G→A A387V (GCC→GTC)  lacZ ← beta‑galactosidase
RA 365,222 G→A P362S (CCT→TCT)  lacZ ← beta‑galactosidase
RA 365,959 G→A P116L (CCC→CTC)  lacZ ← beta‑galactosidase
RA 366,121 G→A A62V (GCC→GTC)  lacZ ← beta‑galactosidase
RA 369,838 G→A A410T (GCG→ACG)  mhpA → 3‑(3‑hydroxyphenyl)propanoate hydroxylase
RA 371,869 G→A E211K (GAA→AAA)  mhpC → 2‑hydroxy‑6‑ketonona‑2,4‑dienedioate hydrolase
RA 372,529 G→A V139M (GTG→ATG)  mhpD → 2‑hydroxypentadienoate hydratase
RA 373,341 G→A A141T (GCG→ACG)  mhpF → acetaldehyde dehydrogenase (acetylating) MhpF
RA 373,985 C→T R40C (CGC→TGC)  mhpE → 4‑hydroxy‑2‑oxovalerate aldolase
RA 374,227 C→T A120A (GCC→GCT mhpE → 4‑hydroxy‑2‑oxovalerate aldolase
RA 380,022 (G)10→9 intergenic (‑141/+47) frmR ← / ← yaiO DNA‑binding transcriptional repressor FrmR/outer membrane protein YaiO
RA 382,571 G→A E300K (GAA→AAA)  insD1 → IS2 element protein
RA 382,943 G→A C331C (TGC→TGT yaiP ← putative glucosyltransferase
RA 384,839 G→A intergenic (‑223/‑393) yaiS ← / → tauA putative deacetylase YaiS/taurine ABC transporter periplasmic binding protein
RA 385,382 G→A A51T (GCA→ACA)  tauA → taurine ABC transporter periplasmic binding protein
RA 386,290 G→A E28E (GAG→GAA tauB → taurine ABC transporter ATP binding subunit
RA 387,624 G→A E218E (GAG→GAA tauC → taurine ABC transporter membrane subunit
RA 398,073 G→A G68R (GGG→AGG)  yaiW → surface‑exposed outer membrane lipoprotein
RA 398,494 G→A G208D (GGC→GAC)  yaiW → surface‑exposed outer membrane lipoprotein
RA 400,495 G→A V143V (GTC→GTT ddlA ← D‑alanine‑‑D‑alanine ligase A
RA 403,108 G→A L454L (CTG→CTA phoA → alkaline phosphatase
RA 409,770 G→A L84L (CTG→TTG)  rdgC ← nucleoid‑associated protein RdgC
RA 413,029 G→A H909Y (CAT→TAT)  sbcC ← ATP‑dependent structure‑specific DNA nuclease ‑ SbcC subunit
RA 431,516 A→C Y166* (TAT→TAG tsx ← nucleoside‑specific channel‑forming protein Tsx
RA 456,227 G→A E365E (GAG→GAA tig → trigger factor
RA 462,281 G→A A123T (GCG→ACG)  ppiD → periplasmic folding chaperone
RA 466,958 C→T D119N (GAT→AAT)  ybaE ← uncharacterized protein YbaE
RA 469,111 C→T L81L (CTG→TTG)  mdlA → ABC transporter family protein MdlA
RA 479,319 G→A intergenic (‑68/+48) ylaC ← / ← maa putative inner membrane protein/maltose O‑acetyltransferase
RA 480,295 2 bp→AA coding (13‑14/219 nt) hha ← hemolysin expression‑modulating protein Hha
JC JC 480,334 IS5 (+) +4 bp coding (372‑375/375 nt) tomB ← Hha toxicity modulator TomB
RA 481,984 G→A S807F (TCT→TTT)  acrB ← multidrug efflux pump RND permease AcrB
RA 481,990 G→A S805F (TCC→TTC)  acrB ← multidrug efflux pump RND permease AcrB
RA 490,181 G→A L31L (CTG→TTG)  ybaM ← DUF2496 domain‑containing protein YbaM
RA 498,400 G→A A116T (GCA→ACA)  hemH → ferrochelatase
RA 501,781 G→A I486I (ATC→ATT ybaL ← putative transporter YbaL
RA 515,925 G→A E3K (GAA→AAA)  fetA → putative iron ABC exporter ATP‑binding subunit FetA
RA 524,376 G→A V372V (GTG→GTA rhsD → protein RhsD
RA 527,575 G→A intergenic (+34/‑6) rhsD → / → ybbC protein RhsD/PF15631 family protein YbbC
RA 528,092 G→A intergenic (+143/+1553) ybbC → / ← ylbG PF15631 family protein YbbC/putative DNA‑binding transcriptional regulator YlbG
RA 528,534 G→A intergenic (+585/+1111) ybbC → / ← ylbG PF15631 family protein YbbC/putative DNA‑binding transcriptional regulator YlbG
RA 531,590 G→A A211V (GCC→GTC)  allS ← DNA‑binding transcriptional activator AllS
JC JC 552,785 IS150 (+) +3 bp coding (314‑316/510 nt) purE ← N(5)‑carboxyaminoimidazole ribonucleotide mutase
RA 558,686 G→A G159S (GGC→AGC)  sfmA → putative fimbrial protein SfmA
RA 559,732 G→A R12R (AGG→AGA sfmD → putative fimbrial usher protein SfmD
RA 567,992 G→A K285K (AAG→AAA insF3 → IS3 element protein InsF
RA 570,416 G→A E505E (GAG→GAA ybcK → putative recombinase YbcK
JC JC 607,765 IS150 (+) +3 bp noncoding (26‑28/60 nt) sokE ← small RNA SokE
RA 639,702 G→A intergenic (+194/‑51) ahpC → / → ahpF alkyl hydroperoxide reductase, AhpC component/alkyl hydroperoxide reductase, AhpF component
RA 640,502 C→A L250L (CTC→CTA ahpF → alkyl hydroperoxide reductase, AhpF component
RA 662,602 G→A P14L (CCT→CTT)  ybeD ← DUF493 domain‑containing protein YbeD
RA 690,948 G→A V279V (GTC→GTT ybeX ← CorC‑HlyC family protein YbeX
RA 692,073 C→T R90H (CGT→CAT)  ybeY ← endoribonuclease YbeY
MC JC 696,507 Δ112 bp glnV glnV
RA 700,038 G→A H97Y (CAT→TAT)  umpH ← UMP phosphatase
RA 731,964 G→A W794* (TGG→TGA rhsC → rhs element protein RhsC
RA 738,681 G→A G197E (GGA→GAA)  ybfD → H repeat‑associated putative transposase YbfD
RA 742,600 G→A intergenic (‑44/‑227) dtpD ← / → ybgI dipeptide:H(+) symporter DtpD/radiation resistance protein YbgI
RA 744,664 G→A G141D (GGC→GAC)  pxpC → 5‑oxoprolinase component C
RA 790,831 G→A P67S (CCC→TCC)  galT ← galactose‑1‑phosphate uridylyltransferase
RA 806,806 G→A P159L (CCT→CTT)  ybhC ← outer membrane lipoprotein YbhC
RA 809,217 2 bp→AG coding (40‑41/1290 nt) bioA ← adenosylmethionine‑8‑amino‑7‑oxononanoate aminotransferase
RA 812,537 G→A E90K (GAG→AAG)  bioD → dethiobiotin synthetase
RA 866,125 G→A S80S (TCC→TCT moeA ← molybdopterin molybdotransferase
RA 896,829 G→A V232V (GTG→GTA potH → putrescine ABC transporter membrane subunit PotH
RA 908,422 G→A G291G (GGC→GGT ltaE ← low‑specificity L‑threonine aldolase
RA 946,493 G→A G208D (GGC→GAC)  ycaD → putative transporter YcaD
RA 968,837 G→A D158N (GAT→AAT)  lpxK → tetraacyldisaccharide 4'‑kinase
RA 974,621 C→T Y101Y (TAC→TAT mukF → chromosome partitioning protein MukF
RA 1,018,193 C→T S36N (AGT→AAT)  ycbZ ← putative ATP‑dependent protease YcbZ
RA 1,022,002 C→T E628K (GAG→AAG)  yccS ← putative transporter YccS
RA 1,023,148 C→T D246N (GAT→AAT)  yccS ← putative transporter YccS
RA 1,035,862 C→T A31A (GCC→GCT hyaD → putative hydrogenase 1 maturation protease HyaD
RA 1,036,085 C→T L106L (CTG→TTG)  hyaD → putative hydrogenase 1 maturation protease HyaD
RA 1,037,810 C→T P24L (CCC→CTC)  appC → cytochrome bd‑II subunit 1
RA 1,040,126 G→T L277L (CTG→CTT appB → cytochrome bd‑II subunit 2
RA 1,043,376 C→T V279M (GTG→ATG)  etk ← protein‑tyrosine kinase Etk
RA 1,048,985 C→T L116L (CTG→CTA gfcB ← lipoprotein GfcB
RA 1,061,935 G→A S46N (AGC→AAC)  torD → trimethylamine‑N‑oxide reductase‑specific chaperone
RA 1,070,014 A→G L114P (CTG→CCG)  rutF ← FMN reductase RutF
RA 1,078,641 A→C F81C (TTT→TGT)  putA ← fused DNA‑binding transcriptional repressor/proline dehydrogenase/1‑pyrroline‑5‑carboxylate dehydrogenase PutA
MC JC 1,095,503 Δ10,045 bp IS3‑mediated ycdU[ymdA] ycdU, serX, ghrA, ycdX, ycdY, ycdZ, csgG, csgF, csgE, csgD, csgB, csgA, csgC, [ymdA]
RA 1,111,727 2 bp→TT coding (865‑866/2544 nt) opgH → osmoregulated periplasmic glucans biosynthesis protein H
JC JC 1,141,668 IS150 (+) +3 bp coding (2698‑2700/3186 nt) rne ← ribonuclease E
JC JC 1,145,135 IS3 (+) +3 bp coding (196‑198/960 nt) rluC → 23S rRNA pseudouridine(955/2504/2580) synthase
RA 1,150,616 C→T L297L (CTG→TTG)  fabD → [acyl‑carrier‑protein] S‑malonyltransferase
RA 1,169,836 A→G L180P (CTG→CCG)  ldtC ← L,D‑transpeptidase LdtC
RA 1,189,980 A→G T156T (ACT→ACC phoP ← DNA‑binding transcriptional dual regulator PhoP
RA 1,196,220 C→T H366H (CAC→CAT icd → isocitrate dehydrogenase
JC JC 1,232,148 IS2 (–) +5 bp coding (963‑967/1269 nt) umuC → DNA polymerase V catalytic protein
RA 1,265,552 G→A G181S (GGT→AGT)  prfA → peptide chain release factor RF1
RA 1,276,230 C→T P463P (CCG→CCA narX ← sensor histidine kinase NarX
JC JC 1,301,713 IS30 (–) +2 bp coding (532‑533/1632 nt) oppA → oligopeptide ABC transporter periplasmic binding protein
RA 1,301,992 A→T N271Y (AAT→TAT)  oppA → oligopeptide ABC transporter periplasmic binding protein
RA 1,306,736 T→G S325A (TCC→GCC)  oppF → murein tripeptide ABC transporter/oligopeptide ABC transporter ATP binding subunit OppF
RA 1,310,770 A→G H32H (CAT→CAC yciI ← protein YciI
RA 1,315,384 G→A Y129Y (TAC→TAT yciF ← DUF892 domain‑containing protein YciF
RA 1,317,129 G→A Q32* (CAG→TAG)  trpA ← tryptophan synthase subunit alpha
RA 1,322,325 G→A L208F (CTC→TTC)  trpE ← anthranilate synthase subunit TrpE
RA 1,337,394 A→G S522G (AGC→GGC)  acnA → aconitate hydratase 1
RA 1,356,932 G→A T60I (ACC→ATC)  sapA ← putative periplasmic binding protein SapA
RA 1,357,202 C→T intergenic (‑92/+221) sapA ← / ← ymjA putative periplasmic binding protein SapA/DUF2543 domain‑containing protein YmjA
RA 1,358,859 T→C Y110C (TAT→TGT)  puuP ← putrescine:H(+) symporter PuuP
RA 1,362,062 C→A T51K (ACG→AAG)  puuR → DNA‑binding transcriptional repressor PuuR
RA 1,366,433 G→A G295D (GGC→GAC)  puuE → 4‑aminobutyrate aminotransferase PuuE
RA 1,388,411 G→A A134V (GCC→GTC)  tpx ← lipid hydroperoxide peroxidase
MC JC 1,397,239 Δ7,448 bp IS5‑mediated ynaJabgA ynaJ, uspE, fnr, ogt, abgT, abgB, abgA
RA 1,464,645 C→T Q59* (CAG→TAG)  paaY → 2‑hydroxycyclohepta‑1,4,6‑triene‑1‑carboxyl‑CoA thioesterase
JC JC 1,477,100 IS5 (+) +4 bp coding (1957‑1960/2307 nt) ydbD → DUF2773 domain‑containing protein YdbD
RA 1,501,192 C→T P207L (CCT→CTT)  tehA → tellurite resistance protein
RA 1,510,574 G→A G191D (GGC→GAC)  ydcR → fused putative DNA‑binding transcriptional regulator/putative aminotransferase YdcR
RA 1,542,527 G→A H22Y (CAC→TAC)  narZ ← nitrate reductase Z subunit alpha
RA 1,582,610 G→T intergenic (‑86/+316) ydeN ← / ← ydeO putative sulfatase YdeN/DNA‑binding transcriptional dual regulator YdeO
JC JC 1,590,147 IS2 (+) +5 bp intergenic (‑146/+703) ydeT ← / ← hipA fimbrial usher domain‑containing protein YdeT/serine/threonine‑protein kinase toxin HipA
RA 1,610,076 T→G D202A (GAT→GCT)  uxaB ← tagaturonate reductase
RA 1,643,679 A→T L209Q (CTG→CAG)  ydfU ← protein YdfU
RA 1,652,331 T→C intergenic (+2346/+397) ydfD → / ← ynfP lysis protein/protein YnfP
RA 1,688,866 G→A Q97Q (CAG→CAA manA → mannose‑6‑phosphate isomerase
RA 1,721,136 C→T L38F (CTT→TTT)  ydhI → DUF1656 domain‑containing protein YdhI
JC JC 1,772,062 IS5 (+) +4 bp coding (992‑995/1215 nt) ydiM → putative exporter YdiM
RA 1,774,952 G→A E89E (GAG→GAA aroD → 3‑dehydroquinate dehydratase
RA 1,776,715 A→T S377C (AGT→TGT)  ydiF → putative acetate‑CoA transferase YdiF
RA 1,815,136 G→A G424S (GGT→AGT)  katE → catalase HPII
JC JC 1,844,254 IS150 (+) +3 bp coding (616‑618/1041 nt) ynjI ← DUF1266 domain‑containing protein YnjI
MC JC 1,867,696 Δ7 bp coding (789‑795/1935 nt) yeaG → protein kinase YeaG
RA 1,894,839 T→C L12P (CTC→CCC)  pabB → aminodeoxychorismate synthase subunit 1
JC JC 1,907,451 IS2 (+) +5 bp coding (137‑141/144 nt) yobF ← DUF2527 domain‑containing protein YobF
RA 1,987,499 C→A intergenic (+71/+8) ftnB → / ← yecJ putative ferritin‑like protein/DUF2766 domain‑containing protein YecJ
RA 2,040,433 C→A A319D (GCC→GAC)  msrP → protein‑L‑methionine sulfoxide reductase catalytic subunit MsrP
RA 2,137,858 G→A intergenic (‑615/‑44) wza ← / → yegH outer membrane polysaccharide export protein Wza/inner membrane protein YegH
RA 2,188,087 T→C T110A (ACG→GCG)  yehA ← putative fimbrial adhesin YehA
RA 2,195,035 G→A A246T (GCG→ACG)  metG → methionine‑‑tRNA ligase
JC JC 2,324,384 IS150 (+) +3 bp coding (276‑278/651 nt) atoA → acetyl‑CoA:acetoacetyl‑CoA transferase subunit beta
RA 2,384,808 C→T K305K (AAG→AAA yfbK ← IPR002035/DUF3520 domain‑containing protein YfbK
RA 2,410,419 G→A L312L (CTG→TTG)  yfbS ← putative transporter YfbS
RA 2,484,827 C→T L152F (CTT→TTT)  evgS → sensor histidine kinase EvgS
MC JC 2,558,699 Δ6,790 bp intZ[eutA] intZ, yffL, yffM, yffN, yffO, yffP, yffQ, yffR, yffS, [eutA]
RA 2,572,542 G→A P322S (CCG→TCG)  eutD ← phosphate acetyltransferase EutD
RA 2,582,490 C→T L96L (TTG→TTA ypfG ← DUF1176 domain‑containing protein YpfG
RA 2,623,776 G→A E245K (GAG→AAG)  ppk → polyphosphate kinase
RA 2,663,960 C→T G173G (GGC→GGT suhB → Nus factor SuhB
RA 2,687,305 C→T G35D (GGC→GAC)  glnB ← nitrogen regulatory protein PII‑1
RA 2,730,889 G→A noncoding (269/1542 nt) rrsG ← 16S ribosomal RNA
RA 2,731,014 C→T noncoding (144/1542 nt) rrsG ← 16S ribosomal RNA
JC JC 2,739,490 IS150 (+) +3 bp coding (578‑580/1122 nt) tyrA ← fused chorismate mutase/prephenate dehydrogenase
RA 2,774,947 G→A G544S (GGT→AGT)  yfjW → uncharacterized protein YfjW
RA 2,837,025 C→T C134Y (TGC→TAC)  hypF ← carbamoyl‑‑[HypE] ligase
RA 2,848,669 C→T L191L (CTG→CTA hycC ← formate hydrogenlyase subunit HycC
RA 2,869,618 C→T E219E (GAG→GAA umpG ← broad specificity 5'(3')‑nucleotidase and polyphosphatase
RA 2,884,038 C→T W34* (TGG→TAG)  casA ← type I‑E CRISPR system Cascade subunit CasA
RA 2,893,165 C→T P170L (CCT→CTT)  ygcN → putative oxidoreductase with FAD/NAD(P)‑binding domain
RA 2,899,607 C→T A223T (GCA→ACA)  ygcW ← putative deoxygluconate dehydrogenase
RA 2,905,688 C→T I44I (ATC→ATT yqcG → cell envelope stress response protein YqcG
JC JC 2,913,392 IS2 (–) +5 bp coding (256‑260/2235 nt) relA ← GDP/GTP pyrophosphokinase
RA 2,924,229 C→T noncoding (296/369 nt) csrB ← small regulatory RNA CsrB
RA 2,926,292 C→T intergenic (+96/‑16) queF → / → ppnN 7‑cyano‑7‑deazaguanine reductase/nucleotide 5'‑monophosphate nucleosidase
RA 2,934,993 C→T R253R (CGC→CGT fucP → L‑fucose:H(+) symporter
RA 2,941,835 G→A Q245* (CAA→TAA)  gcvA ← DNA‑binding transcriptional dual regulator GcvA
RA 2,960,736 C→T A565T (GCT→ACT)  recC ← exodeoxyribonuclease V subunit RecC
RA 2,961,475 C→T E318E (GAG→GAA recC ← exodeoxyribonuclease V subunit RecC
RA 2,964,404 C→T G251D (GGC→GAC)  thyA ← thymidylate synthase
RA 2,974,745 C→T G424S (GGC→AGC)  aas ← fused 2‑acylglycerophospho‑ethanolamine acyltransferase/acyl‑acyl carrier protein synthetase
RA 2,991,238 G→T intergenic (‑878/‑30) yqeK ← / → ygeG protein YqeK/TPR repeat‑containing putative chaperone YgeG
RA 2,991,649 G→A A128T (GCA→ACA)  ygeG → TPR repeat‑containing putative chaperone YgeG
JC JC 3,013,819 IS150 (+) +3 bp coding (419‑421/1626 nt) yqeB ← XdhC‑CoxI family protein YqeB
RA 3,026,438 C→T L225L (CTG→TTG)  guaD → guanine deaminase
RA 3,027,460 C→T P114S (CCT→TCT)  ghxQ → guanine/hypoxanthine transporter GhxQ
RA 3,046,047 C→T intergenic (‑146/+121) ygfF ← / ← gcvP putative oxidoreductase YgfF/glycine decarboxylase
RA 3,048,621 C→T D141N (GAT→AAT)  gcvP ← glycine decarboxylase
RA 3,051,404 C→T G305D (GGC→GAC)  ubiI ← 2‑octaprenylphenol 6‑hydroxylase
RA 3,076,262 C→T E399K (GAA→AAA)  yggP ← putative zinc‑binding dehydrogenase YggP
RA 3,076,704 C→T A251A (GCG→GCA yggP ← putative zinc‑binding dehydrogenase YggP
RA 3,088,010 2 bp→TT intergenic (+150/‑273) metK → / → galP methionine adenosyltransferase/galactose:H(+) symporter
RA 3,099,319 C→T D83N (GAT→AAT)  yggM ← DUF1202 domain‑containing protein YggM
RA 3,102,165 C→T V230I (GTA→ATA)  trmB ← tRNA m(7)G46 methyltransferase
RA 3,103,765 G→A P251P (CCG→CCA mutY → adenine DNA glycosylase
RA 3,104,919 C→T L163L (CTG→TTG)  mltC → membrane‑bound lytic murein transglycosylase C
RA 3,108,369 C→T D263N (GAC→AAC)  speC ← constitutive ornithine decarboxylase
RA 3,108,690 C→T V156I (GTA→ATA)  speC ← constitutive ornithine decarboxylase
RA 3,109,473 A→G intergenic (‑73/‑80) yqgH ← / → yqgA protein YqgH/DUF554 domain‑containing protein YqgA
RA 3,110,945 C→T S61N (AGC→AAC)  yghD ← putative type II secretion system M‑type protein YghD
RA 3,111,094 C→T Q11Q (CAG→CAA yghD ← putative type II secretion system M‑type protein YghD
RA 3,112,577 C→T G158D (GGC→GAC)  yghF ← putative type II secretion system C‑type protein YghF
RA 3,113,320 C→T G53E (GGA→GAA)  yghG ← lipoprotein YghG
RA 3,114,408 C→T intergenic (‑56/+142) pppA ← / ← yghJ prepilin peptidase/putative lipoprotein YghJ
RA 3,115,379 C→T G1245D (GGT→GAT)  yghJ ← putative lipoprotein YghJ
RA 3,116,951 C→T G721E (GGA→GAA)  yghJ ← putative lipoprotein YghJ
RA 3,124,703 C→T A253T (GCG→ACG)  glcF ← glycolate dehydrogenase, putative iron‑sulfur subunit
MC JC 3,131,341 Δ18,049 bp IS5‑mediated [yghQ][yqhA] 19 genes
RA 3,157,803 G→A A52T (GCG→ACG)  yqhG → DUF3828 domain‑containing protein YqhG
RA 3,163,470 G→A I4I (ATC→ATT plsC ← 1‑acylglycerol‑3‑phosphate O‑acyltransferase PlsC
RA 3,166,108 G→A intergenic (‑135/+3) parC ← / ← ygiS DNA topoisomerase IV subunit A/putative deoxycholate binding periplasmic protein
RA 3,166,913 G→A A269V (GCG→GTG)  ygiS ← putative deoxycholate binding periplasmic protein
RA 3,167,825 G→A intergenic (‑107/+26) ygiS ← / ← mqsA putative deoxycholate binding periplasmic protein/antitoxin of the MqsRA toxin‑antitoxin system/DNA‑binding transcriptional repressor MqsA
RA 3,168,872 G→A R120R (CGC→CGT ygiV ← DNA‑binding transcriptional repressor YgiV
RA 3,180,826 G→A E136K (GAA→AAA)  ygiC → putative acid‑‑amine ligase YgiC
RA 3,190,080 G→A G67D (GGC→GAC)  yqiH → putative fimbrial chaperone YqiH
RA 3,212,352 G→A G416S (GGC→AGC)  dnaG → DNA primase
RA 3,215,625 G→A noncoding (28/76 nt) ileX → tRNA‑Ile
RA 3,222,872 G→A W80* (TGG→TGA ebgA → evolved beta‑D‑galactosidase subunit alpha
RA 3,278,700 G→A intergenic (‑35/‑214) agaR ← / → kbaZ DNA‑binding transcriptional repressor AgaR/putative tagatose‑1,6‑bisphosphate aldolase 1 chaperone
RA 3,280,814 G→A intergenic (+124/‑1162) agaV → / → agaS N‑acetyl‑D‑galactosamine specific PTS enzyme IIB component/putative galactosamine‑6‑phosphate deaminase/isomerase
RA 3,284,611 G→A V148I (GTC→ATC)  agaB → galactosamine‑specific PTS enzyme IIB component
RA 3,294,210 G→A V271I (GTA→ATA)  lpoA → outer membrane lipoprotein ‑ activator of MrcA activity
RA 3,295,067 G→A M556I (ATG→ATA lpoA → outer membrane lipoprotein ‑ activator of MrcA activity
RA 3,295,290 G→A A631T (GCA→ACA)  lpoA → outer membrane lipoprotein ‑ activator of MrcA activity
RA 3,300,725 G→A P12S (CCG→TCG)  yhbS ← putative N‑acetyltransferase YhbS
RA 3,307,890 G→A A15V (GCC→GTC)  yrbN ← uncharacterized protein YrbN
RA 3,318,274 G→A noncoding (16/77 nt) metY ← tRNA‑Met
RA 3,323,624 G→A S149S (AGC→AGT glmM ← phosphoglucosamine mutase
RA 3,327,196 G→A P157S (CCA→TCA)  rlmE ← 23S rRNA 2'‑O‑ribose U2552 methyltransferase
JC JC 3,335,208 IS150 (+) +4 bp intergenic (+21/+24) sfsB → / ← murA putative transcriptional regulator SfsB/UDP‑N‑acetylglucosamine 1‑carboxyvinyltransferase
RA 3,336,411 2 bp→AT coding (83‑84/1260 nt) murA ← UDP‑N‑acetylglucosamine 1‑carboxyvinyltransferase
RA 3,347,801 G→A W229* (TGG→TGA rapZ → RNase adaptor protein RapZ
RA 3,348,518 G→A E23K (GAA→AAA)  yrbL → protein kinase‑like domain‑containing protein YrbL
RA 3,351,713 G→A S438F (TCT→TTT)  arcB ← sensor histidine kinase ArcB
RA 3,388,041 T→G T50P (ACG→CCG)  aaeB ← aromatic carboxylic acid efflux pump subunit AaeB
JC JC 3,429,229 IS2 (+) +5 bp intergenic (‑467/‑3) rrsD ← / → yrdA 16S ribosomal RNA/hexapeptide repeat‑containing protein YrdA
RA 3,436,697 G→A E60E (GAG→GAA trkA → NAD‑binding component of Trk potassium transporters
RA 3,472,538 G→A T326I (ACC→ATC)  fusA ← elongation factor G
RA 3,474,425 T→C K43R (AAA→AGA)  rpsL ← 30S ribosomal subunit protein S12
JC JC 3,543,555 IS150 (–) +3 bp coding (389‑391/879 nt) rpnA → recombination‑promoting nuclease RpnA
RA 3,560,455 +G intergenic (+589/+167) rtcR → / ← glpG DNA‑binding transcriptional activator RtcR/rhomboid protease GlpG
RA 3,575,597 G→A G176E (GGA→GAA)  yhgN → MarC family putative inner membrane protein YhgN
RA 3,609,228 C→T F4F (TTC→TTT yhhQ → queuosine precursor transporter
RA 3,628,866 C→T E225K (GAA→AAA)  rbbA ← ribosome‑associated ATPase
RA 3,629,921 C→T E228K (GAG→AAG)  yhiI ← putative membrane fusion protein YhiI
RA 3,635,088 G→A G83E (GGG→GAG)  yhiM → inner membrane protein YhiM
RA 3,635,262 G→A S141N (AGC→AAC)  yhiM → inner membrane protein YhiM
RA 3,636,333 G→A P360S (CCT→TCT)  yhiN ← putative oxidoreductase YhiN
RA 3,639,029 G→A G463D (GGC→GAC)  pitA → metal phosphate:H(+) symporter PitA
RA 3,649,205 G→A G91S (GGT→AGT)  arsB → arsenite/antimonite:H(+) antiporter
RA 3,651,187 G→A intergenic (+525/‑104) arsC → / → yhiS arsenate reductase/putative uncharacterized protein YhiS
RA 3,656,809 G→A intergenic (‑69/‑186) hdeA ← / → hdeD periplasmic acid stress chaperone HdeA/acid‑resistance membrane protein
RA 3,661,261 G→A G283D (GGC→GAC)  mdtF → multidrug efflux pump RND permease MdtF
RA 3,662,374 G→A S654N (AGC→AAC)  mdtF → multidrug efflux pump RND permease MdtF
RA 3,677,340 G→A I337I (ATC→ATT yhjG ← AsmA family protein YhjG
RA 3,682,101 G→A intergenic (‑161/+60) yhjJ ← / ← dctA peptidase M16 family protein YhjJ/C4 dicarboxylate/orotate:H(+) symporter
RA 3,682,515 C→T M311I (ATG→ATA dctA ← C4 dicarboxylate/orotate:H(+) symporter
RA 3,698,073 G→A L16L (CTG→CTA bcsF → putative cellulose biosynthesis protein BcsF
RA 3,702,034 G→A L279F (CTC→TTC)  dppF ← dipeptide ABC transporter ATP binding subunit DppF
RA 3,707,947 C→A intergenic (‑242/+669) dppA ← / ← proK dipeptide ABC transporter periplasmic binding protein/tRNA‑Pro
MC JC 3,708,463 169 bp→A [proK] [proK]
RA 3,715,556 G→A S280F (TCT→TTT)  bisC ← biotin sulfoxide reductase
RA 3,716,798 G→A Q84Q (CAG→CAA yiaD → PF13488 family lipoprotein YiaD
RA 3,721,115 G→A D146N (GAT→AAT)  insJ → insertion element IS150 protein InsA
RA 3,725,176 T→G E48A (GAG→GCG)  glyQ ← glycine‑‑tRNA ligase subunit alpha
RA 3,731,831 G→A G234D (GGT→GAT)  xylF → xylose ABC transporter periplasmic binding protein
RA 3,748,288 G→A G402D (GGC→GAC)  lyxK → L‑xylulose kinase
RA 3,749,010 G→A G145E (GGG→GAG)  sgbH → 3‑keto‑L‑gulonate‑6‑phosphate decarboxylase SgbH
RA 3,755,684 G→A I276I (ATC→ATT aldB ← aldehyde dehydrogenase B
RA 3,759,817 G→A T15T (ACC→ACT selB ← selenocysteyl‑tRNA‑specific translation elongation factor
RA 3,761,230 G→A S7F (TCC→TTC)  selA ← selenocysteine synthase
RA 3,761,858 G→A P33L (CCC→CTC)  yibF ← glutathione transferase‑like protein YibF
RA 3,764,316 G→A G712S (GGT→AGT)  rhsA → rhs element protein RhsA
RA 3,770,330 G→A Y350Y (TAC→TAT yibH ← inner membrane protein YibH
RA 3,771,979 G→T intergenic (‑235/‑302) yibI ← / → mtlA DUF3302 domain‑containing protein YibI/mannitol‑specific PTS enzyme IICBA component
RA 3,781,054 G→A intergenic (+37/‑161) lldD → / → trmL L‑lactate dehydrogenase/tRNA (cytidine/uridine‑2'‑O)‑ribose methyltransferase
RA 3,781,861 G→A T234T (ACC→ACT cysE ← serine acetyltransferase
RA 3,793,266 G→A P140S (CCT→TCT)  htrL ← protein HtrL
RA 3,794,806 G→A A274T (GCG→ACG)  rfaD → ADP‑L‑glycero‑D‑mannoheptose 6‑epimerase
RA 3,795,970 G→A A348T (GCC→ACC)  waaF → ADP‑heptose‑‑LPS heptosyltransferase 2
RA 3,812,665 G→A intergenic (‑106/‑66) yicR ← / → dfp RadC‑like JAB domain‑containing protein YicR/fused 4'‑phosphopantothenoylcysteine decarboxylase and phosphopantothenoylcysteine synthetase
RA 3,815,883 +C coding (667/687 nt) rph ← truncated RNase PH
RA 3,817,598 G→A intergenic (+59/‑162) yicC → / → dinD putative RNase adaptor protein YicC/DNA damage‑inducible protein D
RA 3,819,317 G→A L148L (TTG→TTA yicG → PF03458 family inner membrane protein YicG
JC 3,822,651 (CAGGAT)1→2 coding (252/2109 nt) spoT → bifunctional (p)ppGpp synthase/hydrolase SpoT
RA 3,823,016 G→T R206L (CGC→CTC)  spoT → bifunctional (p)ppGpp synthase/hydrolase SpoT
RA 3,823,162 C→T H255Y (CAC→TAC)  spoT → bifunctional (p)ppGpp synthase/hydrolase SpoT
RA 3,854,009 G→A A30T (GCT→ACT)  emrD → multidrug efflux pump EmrD
RA 3,862,326 G→A Y49Y (TAC→TAT glvB ← putative PTS enzyme II component GlvB
RA 3,862,564 G→A A347V (GCC→GTC)  glvC ← putative PTS enzyme II component GlvC
RA 3,864,161 G→A G88E (GGA→GAA)  yidP → putative DNA‑binding transcriptional regulator YidP
RA 3,864,357 G→A L153L (CTG→CTA yidP → putative DNA‑binding transcriptional regulator YidP
RA 3,865,538 G→A P246S (CCT→TCT)  yidE ← putative transport protein YidE
RA 3,869,637 C→A L87L (CTC→CTA cbrA → colicin M resistance protein
RA 3,871,022 C→T V237M (GTG→ATG)  dgoT ← D‑galactonate:H(+) symporter
RA 3,871,363 G→A P123L (CCG→CTG)  dgoT ← D‑galactonate:H(+) symporter
RA 3,872,298 C→T G234D (GGT→GAT)  dgoD ← D‑galactonate dehydratase
RA 3,873,615 G→A A287V (GCT→GTT)  dgoK ← 2‑dehydro‑3‑deoxygalactonokinase
RA 3,873,698 G→A Y259Y (TAC→TAT dgoK ← 2‑dehydro‑3‑deoxygalactonokinase
RA 3,873,892 G→A L195F (CTT→TTT)  dgoK ← 2‑dehydro‑3‑deoxygalactonokinase
RA 3,875,237 G→A intergenic (‑77/‑201) dgoR ← / → yidX DNA‑binding transcriptional regulator DgoR/putative lipoprotein YidX
RA 3,876,181 C→T D258N (GAT→AAT)  yidA ← sugar phosphatase YidA
RA 3,876,817 G→A P46S (CCG→TCG)  yidA ← sugar phosphatase YidA
RA 3,878,267 G→A A618V (GCT→GTT)  gyrB ← DNA gyrase subunit B
RA 3,878,536 G→A Y528Y (TAC→TAT gyrB ← DNA gyrase subunit B
RA 3,879,384 C→T E246K (GAA→AAA)  gyrB ← DNA gyrase subunit B
RA 3,883,804 G→A intergenic (‑75/‑222) dnaA ← / → ysdD chromosomal replication initiator protein DnaA/protein YsdD
RA 3,883,818 G→A intergenic (‑89/‑208) dnaA ← / → ysdD chromosomal replication initiator protein DnaA/protein YsdD
RA 3,893,459 C→T A232V (GCT→GTT)  yidZ → DNA‑binding transcriptional dual regulator YidZ
RA 3,894,943 C→T L98F (CTT→TTT)  yieF → quinone reductase
RA 3,896,736 G→A intergenic (‑127/‑38) adeP ← / → yieH adenine:H(+) symporter/6‑phosphogluconate phosphatase
RA 3,898,481 G→A D154N (GAT→AAT)  cbrC → PF03691 family colicin E2 tolerance protein CbrC
RA 3,902,025 G→A R66C (CGT→TGT)  bglH ← carbohydrate‑specific outer membrane porin, cryptic
RA 3,909,205 G→A L79L (CTG→TTG)  pstA ← phosphate ABC transporter membrane subunit PstA
RA 3,912,074 G→A S532F (TCC→TTC)  glmS ← L‑glutamine‑‑D‑fructose‑6‑phosphate aminotransferase
RA 3,913,223 G→A A149V (GCT→GTT)  glmS ← L‑glutamine‑‑D‑fructose‑6‑phosphate aminotransferase
RA 3,915,731 G→A A81V (GCC→GTC)  atpC ← ATP synthase F1 complex subunit epsilon
RA 3,916,773 G→A D201D (GAC→GAT atpD ← ATP synthase F1 complex subunit beta
RA 3,917,983 G→A L95L (CTG→TTG)  atpG ← ATP synthase F1 complex subunit gamma
RA 3,922,501 G→A intergenic (‑61/+556) atpI ← / ← rsmG ATP synthase accessory factor AtpI/16S rRNA m(7)G527 methyltransferase
RA 3,923,432 G→A L83L (CTC→CTT rsmG ← 16S rRNA m(7)G527 methyltransferase
RA 3,924,585 G→A P350L (CCT→CTT)  mnmG ← 5‑carboxymethylaminomethyluridine‑tRNA synthase subunit MnmG
RA 3,929,502 G→A V34V (GTC→GTT viaA ← protein ViaA
RA 3,931,952 G→A V213I (GTT→ATT)  kup → K(+):H(+) symporter Kup
RA 3,932,957 G→A V548I (GTA→ATA)  kup → K(+):H(+) symporter Kup
RA 3,933,173 G→A V620I (GTC→ATC)  kup → K(+):H(+) symporter Kup
RA 3,940,517 G→A T32T (ACC→ACT hsrA ← putative transporter HsrA
RA 3,941,924 G→A noncoding (117/1542 nt) rrsC → 16S ribosomal RNA
RA 3,949,381 C→T E197K (GAA→AAA)  yifB ← putative magnesium chelatase YifB
RA 3,959,263 C→T L432L (CTG→TTG)  ilvC → ketol‑acid reductoisomerase (NADP(+))
RA 3,961,943 G→A E423K (GAG→AAG)  rep → ATP‑dependent DNA helicase Rep
RA 3,963,162 G→A I356I (ATC→ATT gpp ← guanosine‑5'‑triphosphate,3'‑diphosphate phosphatase
RA 3,969,294 G→A M88I (ATG→ATA wzzE → enterobacterial common antigen polysaccharide co‑polymerase
RA 3,972,573 G→A V18M (GTG→ATG)  rffG → dTDP‑glucose 4,6‑dehydratase 2
RA 3,987,168 C→T A239T (GCG→ACG)  hemY ← protein HemY
RA 3,989,779 C→T S17N (AGC→AAC)  hemD ← uroporphyrinogen‑III synthase
RA 3,993,531 T→C R793R (CGT→CGC cyaA → adenylate cyclase
RA 3,996,049 T→A L156* (TTG→TAG)  yigA → DUF484 domain‑containing protein YigA
RA 4,011,802 C→T P243S (CCG→TCG)  bioP → biotin transporter
RA 4,029,054 C→T V640M (GTG→ATG)  fadB ← multifunctional enoyl‑CoA hydratase, 3‑hydroxyacyl‑CoA epimerase, Delta(3)‑cis‑ Delta(2)‑trans‑enoyl‑CoA isomerase, L‑3‑hydroxyacyl‑CoA dehydrogenase
RA 4,032,682 C→T S64F (TCT→TTT)  yigZ → IMPACT family member YigZ
RA 4,037,229 C→T intergenic (+12/‑31) ileT → / → alaT tRNA‑Ile/tRNA‑Ala
RA 4,084,903 T→G N307T (AAC→ACC)  fdoG ← formate dehydrogenase O subunit alpha
RA 4,092,703 A→G F41L (TTC→CTC)  frvA ← putative PTS enzyme IIA component FrvA
RA 4,093,564 C→T V237I (GTA→ATA)  rhaD ← rhamnulose‑1‑phosphate aldolase
RA 4,113,851 G→A H208Y (CAT→TAT)  fpr ← flavodoxin/ferredoxin‑NADP(+) reductase
RA 4,123,923 +A coding (534/1026 nt) cytR ← DNA‑binding transcriptional repressor CytR
RA 4,133,661 C→T intergenic (+155/‑174) metF → / → katG 5,10‑methylenetetrahydrofolate reductase/catalase/hydroperoxidase HPI
RA 4,143,377 C→T S283L (TCA→TTA)  frwC → putative PTS enzyme IIC component FrwC
RA 4,161,248 G→T G61V (GGC→GTC)  fabR → DNA‑binding transcriptional repressor FabR
RA 4,164,123 C→G A162G (GCA→GGA)  btuB → cobalamin outer membrane transporter
RA 4,164,339 G→A W234* (TGG→TAG)  btuB → cobalamin outer membrane transporter
RA 4,164,868 G→A G410G (GGG→GGA btuB → cobalamin outer membrane transporter
RA 4,215,142 G→A W288* (TGG→TAG)  metA → homoserine O‑succinyltransferase
RA 4,215,347 T→A intergenic (+138/‑131) metA → / → aceB homoserine O‑succinyltransferase/malate synthase A
RA 4,217,894 C→T F262F (TTC→TTT aceA → isocitrate lyase
RA 4,223,638 T→C intergenic (‑10/‑190) iclR ← / → metH DNA‑binding transcriptional repressor IclR/cobalamin‑dependent methionine synthase
RA 4,282,332 (A)5→6 coding (744/1293 nt) yjcF ← pentapeptide repeat‑containing protein YjcF
RA 4,293,781 2 bp→AT coding (239‑240/597 nt) nrfG → putative formate‑dependent nitrite reductase complex subunit NrfG
RA 4,296,381 +GC intergenic (+587/+55) gltP → / ← yjcO glutamate/aspartate : H(+) symporter GltP/Sel1 repeat‑containing protein YjcO
RA 4,313,171 C→T intergenic (‑180/‑179) alsR ← / → rpiB DNA‑binding transcriptional repressor AlsR/allose‑6‑phosphate isomerase/ribose‑5‑phosphate isomerase B
RA 4,325,644 C→T S33N (AGC→AAC)  yjdN ← PF06983 family protein YjdN
JC JC 4,365,462 IS150 (–) +3 bp intergenic (‑106/+8) cutA ← / ← dcuA copper binding protein CutA/C4‑dicarboxylate transporter DcuA
JC JC 4,370,658 IS150 (+) +3 bp intergenic (‑246/‑28) yjeH ← / → groS L‑methionine/branched chain amino acid exporter/cochaperonin GroES
RA 4,375,746 G→A M16I (ATG→ATA efp → protein chain elongation factor EF‑P
RA 4,384,822 C→T F328F (TTC→TTT yjeM → putative transporter YjeM
JC JC 4,385,870 IS2 (–) +5 bp coding (167‑171/315 nt) yjeO → DUF2645 domain‑containing inner membrane protein YjeO
RA 4,389,397 C→T V322I (GTC→ATC)  psd ← phosphatidylserine decarboxylase proenzyme
RA 4,392,997 G→A V357V (GTC→GTT queG ← epoxyqueuosine reductase
RA 4,393,552 G→A F172F (TTC→TTT queG ← epoxyqueuosine reductase
RA 4,396,373 C→T T103T (ACC→ACT amiB → N‑acetylmuramoyl‑L‑alanine amidase B
RA 4,396,772 T→C F236F (TTT→TTC amiB → N‑acetylmuramoyl‑L‑alanine amidase B
RA 4,409,368 G→A E32K (GAA→AAA)  rlmB → 23S rRNA 2'‑O‑ribose G2251 methyltransferase
RA 4,414,939 G→A S222N (AGC→AAC)  aidB → putative acyl‑CoA dehydrogenase AidB
RA 4,422,585 G→A V134I (GTT→ATT)  ulaD → 3‑keto‑L‑gulonate‑6‑phosphate decarboxylase UlaD
RA 4,425,688 C→A H57N (CAC→AAC)  priB → primosomal replication protein N
RA 4,425,696 C→A N59K (AAC→AAA priB → primosomal replication protein N
JC JC 4,430,711 IS150 (–) +3 bp coding (848‑850/1413 nt) cycA → D‑serine/alanine/glycine/:H(+)symporter
RA 4,432,775 G→A S94S (TCC→TCT ytfF ← inner membrane protein YtfF
RA 4,443,596 G→A W405* (TGG→TGA tamA → translocation and assembly module subunit TamA
RA 4,460,950 C→T G571S (GGT→AGT)  nrdD ← anaerobic ribonucleoside‑triphosphate reductase
RA 4,465,585 G→A S199F (TCT→TTT)  treB ← trehalose‑specific PTS enzyme IIBC component
RA 4,473,900 C→T G52R (GGA→AGA)  bdcA ← c‑di‑GMP‑binding biofilm dispersal mediator protein
RA 4,475,024 C→T P55S (CCG→TCG)  tabA → DUF386 domain‑containing toxin‑antitoxin biofilm protein TabA
RA 4,475,493 T→C F19F (TTT→TTC yjgL → protein YjgL
RA 4,484,224 G→A S19S (AGC→AGT holC ← DNA polymerase III subunit chi
RA 4,488,217 G→A L300L (CTG→CTA lptG → lipopolysaccharide transport system protein LptG
RA 4,496,431 A→G noncoding (27/85 nt) leuX → tRNA‑Leu
RA 4,496,440 A→T noncoding (36/85 nt) leuX → tRNA‑Leu
RA 4,496,466 G→A noncoding (62/85 nt) leuX → tRNA‑Leu
RA 4,499,501 G→A intergenic (+1/‑1759) insD6 → / → yjgZ IS2 insertion element protein InsB/uncharacterized protein YjgZ
RA 4,510,238 T→G intergenic (+445/+452) insO → / ← fecE IS911B regulator fragment/ferric citrate ABC transporter ATP binding subunit
RA 4,512,541 C→T G290E (GGG→GAG)  fecC ← ferric citrate ABC transporter membrane subunit FecC
RA 4,512,767 C→T A215T (GCG→ACG)  fecC ← ferric citrate ABC transporter membrane subunit FecC
RA 4,518,043 G→A L65F (CTC→TTC)  fecI ← RNA polymerase sigma factor FecI
RA 4,523,224 G→A L291F (CTC→TTC)  yjhG ← D‑xylonate dehydratase
RA 4,523,244 C→T G284D (GGC→GAC)  yjhG ← D‑xylonate dehydratase
RA 4,531,425 C→T R76H (CGC→CAC)  sgcX ← putative endoglucanase with Zn‑dependent exopeptidase domain
RA 4,532,409 T→G intergenic (‑758/+28) sgcX ← / ← yjhP putative endoglucanase with Zn‑dependent exopeptidase domain/putative methyltransferase YjhP
RA 4,536,716 C→T W293* (TGG→TGA nanS ← N‑acetyl‑9‑O‑acetylneuraminate esterase
JC JC 4,542,448 IS5 (–) +4 bp coding (412‑415/597 nt) fimE → regulator for fimA
RA 4,546,601 C→T I502I (ATC→ATT fimD → type I fimbriae usher protein
RA 4,553,339 C→T L147L (CTG→TTG)  uxuB → D‑mannonate oxidoreductase
RA 4,560,446 C→T G79S (GGC→AGC)  yjiH ← uncharacterized protein YjiH
RA 4,571,116 C→T E153E (GAG→GAA yjiR ← fused putative DNA‑binding transcriptional regulator/putative aminotransferase YjiR
RA 4,577,627 C→T S111N (AGC→AAC)  mcrC ← Type IV methyl‑directed restriction enzyme EcoKMcrBC subunit
RA 4,578,534 C→T E268E (GAG→GAA
E268E (GAG→GAA
mcrB ←
mcrB ←
5‑methylcytosine‑specific restriction enzyme subunit McrB
5‑methylcytosine‑specific restriction enzyme subunit McrB
RA 4,584,958 C→T A602T (GCC→ACC)  hsdR ← type I restriction enzyme EcoKI endonuclease subunit
RA 4,589,433 C→T G616D (GGC→GAC)  btsT ← pyruvate:H(+) symporter
RA 4,593,756 C→T G323R (GGG→AGG)  lgoT ← galactonate:H(+) symporter
RA 4,599,184 C→T G86G (GGG→GGA opgB ← phosphoglycerol transferase I
RA 4,605,340 C→T M108I (ATG→ATA fhuF ← ferric‑siderophore reductase FhuF
RA 4,609,336 (C)7→8 intergenic (+13/‑78) yjjG → / → prfC pyrimidine 5'‑nucleotidase YjjG/peptide chain release factor RF3
RA 4,622,949 G→A S394N (AGC→AAC)  yjjJ → toxin YjjJ
RA 4,623,854 G→A T88T (ACC→ACT lplA ← lipoate‑‑protein ligase A
RA 4,632,342 C→T S537F (TCT→TTT)  slt → soluble lytic murein transglycosylase
RA 4,636,925 G→C R77P (CGC→CCC)  creC → sensory histidine kinase CreC
RA 4,638,240 G→A L21L (TTG→TTA creD → putative inner membrane protein CreD

Unassigned missing coverage evidence
   seq id start end size ←reads reads→ gene description
* * ÷ NC_000913 257823 258675–257909 87–853 160 [0] [0] 113 crl–insA9 crl,insB9,insA9
* * ÷ NC_000913 1196232 1211459 15228 43 [38] [37] 39 [icd]–mcrA [icd],C0293,ymfD,ymfE,lit,intE,xisE,ymfH,ymfI,ymfJ,ymfK,ymfT,ymfL,ymfM,ymfN,ymfR,beeE,ymfQ,ycfK,tfaP,tfaE,pinE,mcrA
* * ÷ NC_000913 1492145 1492210 66 108 [0] [0] 132 [sokB] [sokB]
* * ÷ NC_000913 1978495 1979270 776 134 [0] [0] 154 insB5–insA5 insB5,insA5
* * ÷ NC_000913 2170353–2171427 2175000 3574–4648 39 [37] [0] 86 [insE5]–[gatA] [insE5],insF5,gatR,gatD,gatB,[gatA]
* * ÷ NC_000913 2755517 2755750 234 45 [35] [37] 39 [ssrA] [ssrA]
* * ÷ NC_000913 3223868 3262483 38616 102 [0] [0] 108 [ebgA]–[tdcD] [ebgA],ebgC,ygjI,ygjJ,ygjK,fadH,higA,higB,rlmG,ygjP,ygjQ,ygjR,alx,sstT,ygjV,uxaA,uxaC,exuT,exuR,yqiM,yqjA,mzrA,yqjC,yqjD,yqjE,yqjK,yqjF,yqjG,yhaH,yhaI,yhaJ,yhaK,yhaL,cyuA,cyuP,tdcG,tdcF,tdcE,[tdcD]
* * ÷ NC_000913 3423806–3424233 3424460–3424238 6–655 40 [38] [38] 39 [rrlD] [rrlD]

Unassigned new junction evidence
  seq id position reads (cov) reads (cov) score skew freq annotation gene product
* ? NC_000913 = 2578220 (0.000)158 (1.480) 89/598 0.0 100% intergenic (+51/‑7) frsA/crl fermentation‑respiration switch protein/RNA polymerase holoenzyme assembly factor Crl
?NC_000913 = 382590 NA (NA)noncoding (1331/1331 nt) IS2 repeat region
* ? NC_000913 258676 =0 (0.000)77 (0.990)
+81 bp
50/436 0.2 100% pseudogene (1/331 nt) crl RNA polymerase holoenzyme assembly factor Crl
?NC_000913 = 1469241 NA (NA)intergenic (‑92/‑5) insC2/ydbA IS2 insertion element repressor InsA/putative outer membrane protein, N‑terminal fragment
* ? NC_000913 = 12994980 (0.000)144 (1.360) 101/590 0.0 100% intergenic (+253/‑69) ychE/insH21 MarC family putative inner membrane protein YchE/IS5 family transposase and trans‑activator
?NC_000913 1300698 = 0 (0.000)intergenic (+151/‑484) insH21/oppA IS5 family transposase and trans‑activator/oligopeptide ABC transporter periplasmic binding protein
* ? NC_000913 = 1397238NA (NA)134 (1.250) 91/598 0.0 100% noncoding (1195/1195 nt) IS5 repeat region
?NC_000913 = 1978494 0 (0.000)intergenic (‑297/+24) flhD/insB5 DNA‑binding transcriptional dual regulator FlhD/IS1 family protein InsB
* ? NC_000913 = 14921440 (0.000)108 (1.020) 69/592 0.2 100% noncoding (26/57 nt) sokB putative small regulatory RNA antitoxin SokB
?NC_000913 = 3722075 NA (NA)noncoding (1443/1443 nt) IS150 repeat region
* ? NC_000913 1492211 =0 (0.000)132 (1.240) 79/594 0.1 100% intergenic (+36/‑259) sokB/trg putative small regulatory RNA antitoxin SokB/methyl‑accepting chemotaxis protein Trg
?NC_000913 3720633 = NA (NA)noncoding (1/1443 nt) IS150 repeat region
* ? NC_000913 1979271 =0 (0.000)154 (1.440) 97/598 0.0 100% intergenic (‑56/‑482) insA5/uspC IS1 family protein InsA/universal stress protein C
?NC_000913 = 2102947 NA (NA)pseudogene (443/446 nt) wbbL interrupted rhamnosyltransferase WbbL
* ? NC_000913 = 2170611NA (NA)86 (0.810) 54/594 0.7 100% noncoding (441/1258 nt) IS3 repeat region
?NC_000913 2175001 = 0 (0.000)coding (49/453 nt) gatA galactitol‑specific PTS enzyme IIA component
* ? NC_000913 2288919 =NA (NA)108 (1.010) 65/596 0.3 100% noncoding (1195/1195 nt) IS5 repeat region
?NC_000913 3262484 = 0 (0.000)coding (1177/1209 nt) tdcD propionate kinase
* ? NC_000913 3130146 =NA (NA)102 (0.950) 68/598 0.2 100% noncoding (1/1195 nt) IS5 repeat region
?NC_000913 = 3223867 0 (0.000)coding (1235/3093 nt) ebgA evolved beta‑D‑galactosidase subunit alpha
* ? NC_000913 4542682 =79 (0.740)67 (0.650) 48/580 0.9 46.8% intergenic (+49/‑433) fimE/fimA regulator for fimA/type 1 fimbriae major subunit
?NC_000913 4542996 = 76 (0.730)intergenic (+363/‑119) fimE/fimA regulator for fimA/type 1 fimbriae major subunit
* ? NC_000913 = 454269085 (0.790)52 (0.500) 39/580 1.5 39.6% intergenic (+57/‑425) fimE/fimA regulator for fimA/type 1 fimbriae major subunit
?NC_000913 = 4542986 76 (0.730)intergenic (+353/‑129) fimE/fimA regulator for fimA/type 1 fimbriae major subunit