Strain Name: utut / Allele: s357

Allele s357
Strain Name utut
Type Mutant
Genotype ututs357
Affected Gene Not identified
Origin and Depositor University of California San Francisco (Dr. Akira Muto)
Present affiliation: National Institute of Genetics
Link to ZFIN ZDB-GENO-050617-15    
Information
1. Melanosomes are expanded slightly even in a light-adapting condition (so called visual background adaptation (VBA) defect).
2. Mutants show reduced optokinetic response (OKR) for several minutes after return to the light from a 45 min dark treatment. The responsiveness is recovered by 30-60 min under the light adapting condition.
Examination of mutant : Mutant larvae (5-7dpf) show weak VBA defect.
Viability: Adult-viable.  
The Conditions to Distribute Strains
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Muto A, et al. (2005) Forward Genetic Analysis of Visual Behavior in Zebrafish. PLoS Genet 1(5):e66  
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Reference

Akira Muto, Michael B Orger, Ann M Wehman, Matthew C Smear, Jeremy N Kay, Patrick S Page-McCaw, Ethan Gahtan, Tong Xiao, Linda M Nevin, Nathan J Gosse, Wendy Staub, Karin Finger-Baier, Herwig Baier. Forward genetic analysis of visual behavior in zebrafish. PLoS Genet. 2005 ; 1(5) : 575-588 .

Ziv L, Muto A, Schoonheim PJ, Meijsing SH, Strasser D, Ingraham HA, Schaaf MJ, Yamamoto KR, Baier H. An affective disorder in zebrafish with mutation of the glucocorticoid receptor. Mol. Psychiatry. 2013 ; 18(6) : 681-691 .

Griffiths BB, Schoonheim PJ, Ziv L, Voelker L, Baier H, Gahtan E. A zebrafish model of glucocorticoid resistance shows serotonergic modulation of the stress response. Front Behav Neurosci. 2012 ; 6() : 68 .

 
Facility RIKEN Center for Brain Science