Strain Name: half baked / Allele: rk3

Allele rk3
Strain Name half baked
Type Mutant
Genotype cdh1rk3/rk3
Affected Gene E-cadherin,epithelial
Origin and Depositor RIKEN CDB (Masahiko Hibi) Present affiliation :Nagoya University
Link to ZFIN ZDB-GENO-050826-2    
Information
half baked is an epiboly-defective mutant. There is a mutation in the splicing acceptor of the first intron in the rk3 allele and it is hypomorphic and temperature-sensitive. E-cadherin/Cadherin1 is involved in adhesion between the deep cells and the enveloping layer.  
The Conditions to Distribute Strains
"In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Shimizu, et al., E-cadherin is required for gastrulation cell movements in zebrafish. Mech. Dev. 122(6):747-763
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested."  
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Reference

Shimizu T, Yabe T, Muraoka O, Yonemura S, Aramaki S, Hatta K, Bae YK, Nojima H, Hibi M. E-cadherin is required for gastrulation cell movements in zebrafish. Mech. Dev. 2005 ; 122(6) : 747-763 .

 
Facility RIKEN Center for Brain Science