Predicted mutation
evidence	seq id	position	mutation	annotation	gene	description
RA	NC_000913	233,353	C→T	R201R (CGG→CGA)	mltD ←	membrane‑bound lytic murein transglycosylase D

Read alignment evidence...
	seq id	position		ref	new	freq	score (cons/poly)	reads	annotation	genes	product
*	NC_000913	233,353	0	C	T	97.0%	94.2 / ‑6.3	33	R201R (CGG→CGA)	mltD	membrane‑bound lytic murein transglycosylase D
Reads supporting (aligned to +/- strand):  ref base C (0/0);  major base T (16/16);  minor base A (0/1);  total (16/17)
Fisher's exact test for biased strand distribution p-value = 1.00e+00
Kolmogorov-Smirnov test that lower quality scores support variant p-value = 1.00e+00

CTTGCTGACGGAAATCCCCGCCATATCTGCTACCTTCGCCATTTCAACCGGGCTGCTCAGGTGCACACGCGCCAGAGCACGGCTTTCATCGGTCGTTGGCAGACGTACGCCATAACGCTTGCTGTTTTTGAGAA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACCCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGACGCGCGTCATAATTGCGGGTCTGTTTCAAACCATAATTGCGCCCCGTGCTCGGAATGATCTGCCAGATGCCTGCGGCATTGGCGCCAGACGTTGCGTGAGGATCAAAAGCGCTCTCCACTATGGG  >  NC_000913/233104‑233592                                                                                                                                                                                                                                                           |                                                                                                                                                                                                                                                tttgcttcggacattcaccGCCATATCTGCTACCTTCGCCATGTCCACCGGGCTGCTCAGGTGCACACGCGCCAGAGCACGTCTTTCATCGGTCGTTGGCAGACGTCCGCCATAACGCTTGCTGTTTTTGAGAA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGAcc                                                                                                                                                                                                                                                 <  1:5422/233‑1 (MQ=255)              aTCCCCGCCATATCTGCTCCATAAGCCATTACAACCGGGCTGCTCAAGTGCACACGCGCCAGAGCACGGCTGTCATAGGTTGTTGGCAGACGTACGCCAGAACGCTCGCTGTTTCTG‑GAACTATCACTCAATGCCAGCATTTTCGGCACATACTGCTTAGATTCCTGCGGAAACCGTAACGACCAGAAGTCCGTGGATTTCCCACTCGCTTTGTAAGTTTTTATTGCATTCATGACTCGACATTCGCAGCt                                                                                                                                                                                                                                   >  2:167786/1‑251 (MQ=255)                   cGCCATATCTGCTACCTTCGCCATTTCAACCGGGCTGCTCAGGTGCACACGCGCCAGAGCACGGCTTTCATCGGTCGTTGGCAGACGTACGCCATAACGCTTGCTGTTTTTGAGAA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTtat                                                                                                                                                                                                                              <  1:248552/251‑1 (MQ=255)                    gCCATATCTGCTACCTTCGACATTTCAACCGGGCTGCTCAGGTGCACACGCGCGAGAGCACGGCTTTCATCGGTCGTTTGCAGACGTACGCCATAACGCTTGCTGTTTTTGAGAA‑TATCACTCCATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGACCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTtat                                                                                                                                                                                                                              >  2:231821/1‑250 (MQ=255)                      cATATCTGCTACCCTCGCCATTTCAACCGGGCTGCTCAGGTGCACACGCGCCAGAGCACGGCTTTCATCGGTCGTTGGCAGACGTACGCCATAACGCTTGCTGTTTTTGAGAA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGTCCTTCGCCGCTGTTAAAAg                                                                                                                                                                                                                           <  2:88459/251‑1 (MQ=255)                                 ccTTCGCCATTTCAACCGGGCTGCTCAGGTGCACACGCGCCAGAGCACGGCTTTCATCGGTCGTTGGCAGACGTACGCCATAACGCTTGCTGTTTTTGAGAA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTc                                                                                                                                                                                                                <  1:92330/251‑1 (MQ=255)                                         agttCAGCCGGGCTGCTCAGGTGCACACGCGCCAGAGCACGGCTTTCAGCGGTCGTTGGCAGACGTACGCCATAACGCTTGCTGTTTTTGAGAA‑TATCGCTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGATCAGAAGTCCGTGGATTTCCCACGTGCTTTGTTCGTTTTAATTGCCTGCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCa                                                                                                                                                                                                        <  1:151225/249‑1 (MQ=255)                                         aTTTCAACCGGGCTGCTCAGGTGCACACGCGCCAGAGCACGGCTTTCATCGGTCGTTGGCAGACGTACGCCATAACGCTTGCTGTTTTTGAGAA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGcc                                                                                                                                                                                                         >  1:255456/1‑250 (MQ=255)                                               aCCGGGCTGCTCAGGTGCACCCGCGCCAGAGCACGGCTTTCATCGGTCGTTGGCAGACGTACGCCATAACGCTTGCTGTTTTTGAGAA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGCTTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGcc                                                                                                                                                                                                  >  1:90919/1‑251 (MQ=255)                                                ccGGGCTGCTCAGGTGCACACGCGCCAGAGCACGGCTTTCATCGGTCGTTGGCAGACGTACGCCATAACGCTTGCTGTTTTTGAGAA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCg                                                                                                                                                                                                 >  2:261264/1‑251 (MQ=255)                                                    gctgctCAGGTGCACACGCGCCAGAGCACGGCTTTCATCGGTCGTTGGCAGACGTACGCCATAACGCTTGCTGTTTTTGAGAA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTcgcc                                                                                                                                                                                                                                      <  2:66123/210‑1 (MQ=255)                                                                       gacAGAGCACGGCTTTCATCGGTCGTTGGCAGACGAACGCCATAACGCTTGCTGTTTTTGAGCA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCACCGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGTCCTTCGCCGCTGTTATAAGCCGCTACGGTCAAAATCCAGTCGCACTCAACCATTTTGTTCAGTCGcgg                                                                                                                                                                          >  2:165367/3‑249 (MQ=255)                                                                                                   gCAGACGTACGCCATAACGCTTGCTGTTTTTGAGAA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCATTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGa                                                                                                                                               >  2:97715/1‑250 (MQ=255)                                                                                                       ccGTACGCCATAACGCTTGCTGTTTTTGAGAA‑TAGCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAATCATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGcaa                                                                                                                                          <  2:41272/250‑1 (MQ=255)                                                                                                         gTACGCCATAACGCTTGCTGTTTTTGAGAA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTACGTTTCCTGCGGCAACGGTACCGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGGCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGcaaca                                                                                                                                        <  1:231821/251‑1 (MQ=255)                                                                                                             gCCATAACGCTTGCTGTTTTTGAGAA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTCCGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACAt                                                                                                                                    >  1:51968/1‑251 (MQ=255)                                                                                                                       ttGCTGTTTTTGAGAA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGCTTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGAcgcgc                                                                                                                          >  2:76800/1‑251 (MQ=255)                                                                                                                        tGCTGTTTTTGAGAA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGAcgcg                                                                                                                           <  2:90919/249‑1 (MQ=255)                                                                                                                                 tGAGAA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGACGCGCGTCATAAtt                                                                                                                 <  2:156379/250‑1 (MQ=255)                                                                                                                                   agaA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGACGCGCGTCATAATTGCg                                                                                                              >  1:151638/1‑251 (MQ=255)                                                                                                                                     aa‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGCCGCGCGTCATAATTGCggg                                                                                                            >  1:153140/1‑251 (MQ=255)                                                                                                                                     aa‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGACGCGCGTCATAATTGCggg                                                                                                            >  1:133348/1‑251 (MQ=255)                                                                                                                                           cACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGACGCGCGTCATAATTGCGGGTCTGt                                                                                                       <  2:188543/251‑1 (MQ=255)                                                                                                                                                         aTTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGACGCGCGTCATAATTGCGGGTCTGTTTCAAACCATAAtt                                                                                         >  2:154497/1‑251 (MQ=255)                                                                                                                                                                  aCGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCCCGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGAAGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGCCGCGCGTCATAATTGCGGGTCTGTTTCAAACCATAATTGCGCCCCGt                                                                                >  2:263201/1‑251 (MQ=255)                                                                                                                                                                    ggaCTGCTTCGTTTCCTGCGGCAACGGTAACGACTAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGACGCGCGTCATAATTGCGGGTCTGGTTCAAACCATAATTGCGCCCCGTGc                                                                              <  2:243893/249‑1 (MQ=255)                                                                                                                                                                      aCTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGACGCGCGTCATAATTGCGGGTCTGTTTCAAACCATAATTGCGCCCCGTGCTc                                                                            <  1:154497/251‑1 (MQ=255)                                                                                                                                                                            tcttttCCTTCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGTGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGACGCGCGTCATAATTGCGGGTCTGTTTCAAACCATAATTGCGCCCCGTGCTCGGAAt                                                                       <  1:10638/247‑1 (MQ=255)                                                                                                                                                                              gTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGACGCGCGTCATAATTGCGGGTCTGTTTCAAACCATAATTGCGCCCCGTGCTTGGAATGAt                                                                    >  1:88347/1‑251 (MQ=255)                                                                                                                                                                                 tCCTGCGGCAACGGTAACGACTAGATGTCCATGGATTGCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACACGACCTTCGGCGCGGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCGGGCGCGGCATCATATGCAGGGCGGCAGGTGTTGAAGCAAGAACATGGCGGGGCGCGTCATAATTGCGGGGCGGTTTCAAACCATAATTGCGCCGCGTGCTCGGAATGATCt                                                                  <  2:128651/250‑1 (MQ=255)                                                                                                                                                                                             ggTAACGCCCAGAAGTCCGTGGATTTCCCACGCGATTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGCTATAAGCAGCTCCGGTCAGAAGCCAGTCGACGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGATGTTGAGGCAACAACATCGCGACGCGCGTCATACTTGCGGGACTGTTTCACACCATAATTACGACCCGTGCTCGGAATGTTCTACCCGATGCCTGc                                                     >  2:228739/1‑251 (MQ=255)                                                                                                                                                                                                             ccGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGACGCGCGTCATAATTGCGGGTCTGTTTCAAACCATAATTGCGCCCCGTGCTCGGAATGATCTGCCAGATGCCTGCGGCATTGGCGCCAGa                                      <  1:263201/250‑1 (MQ=255)                                                                                                                                                                                                             ccGTGGATTGCCCTCGCGCTGTGTTCGTTTTAATTGCCTTCAGGACTCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGACGCGCGTCATAATTGCGGGGCTGTTTCAAACCATAATTGCGCCCCGTGCTCGGAATGATCTGCCAGATGCCTGCGGCATTGGCGCCAGAc                                     <  1:169722/251‑1 (MQ=255)                                                                                                                                                                                                                                                gCCTTCATGACTCGACCGTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCGGCATCATATTCAGCGCGGCAGTTGGTGAAGCAACAACATCGCGACGCGCGTCATAATTGCGGGTCTGTTTCAAACCATAATTGCGCCCCGTGCTCGGAATGATCTGCCAGATGCCTGCGGCATTGGCGCCAGACGTGGCGTGAGGATCAAAAGCGCGCTCCACTATggg  <  1:49707/251‑1 (MQ=255)                                                                                                                                                                                                                                                           |                                                                                                                                                                                                                                                CTTGCTGACGGAAATCCCCGCCATATCTGCTACCTTCGCCATTTCAACCGGGCTGCTCAGGTGCACACGCGCCAGAGCACGGCTTTCATCGGTCGTTGGCAGACGTACGCCATAACGCTTGCTGTTTTTGAGAA‑TATCACTCAATGCCAGCATTTTAGGCACGTACTGCTTCGTTTCCTGCGGCAACGGTAACGACCAGAAGTCCGTGGATTTCCCACGCGCTTTGTTCGTTTTAATTGCCTTCATGACCCGACCTTCGCCGCTGTTATAAGCCGCTACGGTCAGAAGCCAGTCGCCGTCAAACATTTTGTTCAGACGCTGCATCATATTCAGCGCGGCAGTTGTTGAAGCAACAACATCGCGACGCGCGTCATAATTGCGGGTCTGTTTCAAACCATAATTGCGCCCCGTGCTCGGAATGATCTGCCAGATGCCTGCGGCATTGGCGCCAGACGTTGCGTGAGGATCAAAAGCGCTCTCCACTATGGG  >  NC_000913/233104‑233592

Alignment Legend
Aligned base mismatch/match (shaded by quality score): ATCG/ATCG < 3 ≤ ATCG/ATCG < 12 ≤ ATCG/ATCG < 14 ≤ ATCG/ATCG < 32 ≤ ATCG/ATCG < 39 ≤ ATCG/ATCG
Unaligned base: atcg    Masked matching base: atcg    Alignment gap: ‑    Deleted base: ‑