|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
|
Deletion
|
DE(ptsI-cysA)137
,
OCL60-7
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
pdxK
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
pdxK
Search strains by all related name:
pdxK b2418 ECK2413 f283 JW2411 pdxL thiJ yfeI
|
General information (Go to Linear View: )
|
|
Gene Name
|
pdxK
|
|
Alternative name
|
b2418,ECK2413,f283,JW2411,pdxL,thiJ,yfeI
|
|
Location, Length
|
2,534,408 - 2,535,259
(
-
)
;
54.62
min
;
852
(bp) ,
283
(aa)
|
|
Product
|
pyridoxal-pyridoxaminekinase/hydroxymethylpyrimidine kinase
|
|
Operon Name
|
pdxK
|
|
Note
|
pyridoxal/pyridoxine/pyridoxamine kinase
|
|
Function
|
enzyme; Biosynthesis of cofactors, carriers: Pyridoxine
|
|
Gene Ontology
|
GO:0000166
;
nucleotide binding ( pdxK )
GO:0000287
;
magnesium ion binding ( pdxK )
GO:0004340
;
glucokinase activity ( pdxK )
GO:0005524
;
ATP binding ( pdxK )
GO:0006096
;
glycolysis ( pdxK )
GO:0008270
;
zinc ion binding ( pdxK )
GO:0008478
;
pyridoxal kinase activity ( pdxK )
GO:0008615
;
pyridoxine biosynthetic process ( pdxK )
GO:0016301
;
kinase activity ( pdxK )
GO:0016740
;
transferase activity ( pdxK )
GO:0046872
;
metal ion binding ( pdxK )
|
|
PID
|
1788758
|
EC number
(KEGG Pathway)
|
2.7.1.35
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
PDXK_ECOLI
(
P40191
;
P76964
)
|
|
- Protein name
|
Pyridoxine kinase
|
|
- Synonyms
|
EC 2.7.1.35, Pyridoxal kinase, Vitamin B6 kinase, Pyridoxamine kinase, PN/PL/PM kinase
|
|
- Gene name
|
Name=pdxK; OrderedLocusNames=b2418;
|
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Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
pdxK
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Crystal Structure Of Pyridoxal Kinase From The Escherichia Coli Pdxk Gene At 2.1 A Resolution
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Pyridoxine kinase
|
|
PSI-BLAST
|
Pyridoxamine kinase
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
pyridoxine kinase [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
|
|
MMBR References
|
FEMS Microbiol Lett. 1996;141(1):89-95.
Identification of the pdxK gene that encodes pyridoxine (vitamin B6) kinase in Escherichia coli K-12.
Yang Y, Zhao G, Winkler ME.
(
8764513
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MSSLLLFNDK SRALQADIVA VQSQVVYGSV GNSIAVPAIK QNGLNVFAVP TVLLSNTPHY DTFYGGAIPD
0071 EWFSGYLRAL QERDALRQLR AVTTGYMGTA SQIKILAEWL TALRKDHPDL LIMVDPVIGD IDSGIYVKPD
0141 LPEAYRQYLL PLAQGITPNI FELEILTGKN CRDLDSAIAA AKSLLSDTLK WVVVTSASGN EENQEMQVVV
0211 VTADSVNVIS HSRVKTDLKG TGDLFCAQLI SGLLKGKALT DAVHRAGLRV LEVMRYTQQH ESDELILPPL
0281 AEA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ttaccttatc cttgttttgt gatagccgat
-070 ttgactgcca gaatcaggta aagtttcggt tggattacga tgaggatcat cggcaaggag aaaaaattaa
0001 atgagtagtt tgttgttgtt taacgataag agtagggcac tgcaggcgga tatcgtcgcc gtgcagtcgc
0071 aggtggttta cggcagcgtg ggcaacagca ttgccgtgcc tgctatcaaa cagaacggcc tgaatgtctt
0141 tgccgtgccg acggtattgc tgagcaatac gccgcattat gacactttct acggtggtgc gattccggac
0211 gaatggttta gcggctattt gcgtgcgctt caggagcgtg atgcgctgcg ccaacttcgt gctgtaacca
0281 cgggctatat gggaacggca tcgcaaatca aaatccttgc cgagtggctg actgcgctac gcaaagacca
0351 tcctgaccta ttgatcatgg tcgatccggt gattggcgat attgatagcg gaatttatgt caaacctgac
0421 cttcccgaag cgtatcgaca atatttactg ccgctggcgc agggaattac ccccaatatc tttgagttgg
0491 aaatcctgac cggtaaaaat tgccgcgatc tcgacagtgc cattgctgcc gcaaaaagtc tgctttcaga
0561 cacattaaaa tgggtggtgg ttaccagcgc ctccggtaat gaagaaaatc aggagatgca ggttgtggtg
0631 gtcactgccg acagcgtgaa tgtcatttcc cattcacggg taaaaaccga cctgaaaggg actggcgacc
0701 tgttttgtgc tcagctcatc agtggcttgc tgaaagggaa ggcgttaacc gatgcagtgc accgagcggg
0771 gttgcgcgta ctggaagtga tgcgctacac ccagcagcat gagagcgatg aattgatttt gccgccgctg
0841 gcggaagcat aaaaaaatgg cgccgatggg cgccattttt cactgcggca agaattactt cttgatgcgg
0911 ataaccgggg tttcacccac ggttacgcta ccggacagtt tg
|
