MG1655
W3110
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Gene Report : cobC
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCR46 (D)  ,  OCR46-11 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  cobC
Related strains
     Strains Search Search strains by gene name:  cobC   Search strains by all related name:  cobC b0638 ECK0631 JW0633 phpB

General information  (Go to Linear View:)
 Gene Name cobC  
 Alternative name b0638,ECK0631,JW0633,phpB  
 Location, Length 668,519 - 669,130 (  -  ) ;   14.41 min ; 612 (bp) ,   203 (aa) Go to Linear View
 Product putative alpha-ribazole-5'-P phosphatase  
 Operon Name leuS-lptE-holA-nadD-cobC  
 Note homolog of Salmonella cobC, a phosphohistidine protein  
 Function putative regulator; Biosynthesis of cofactors, carriers: Cobalamin  
 Gene Ontology GO:0003824 ; catalytic activity ( cobC )
GO:0008152 ; metabolic process ( cobC )
GO:0009236 ; cobalamin biosynthetic process ( cobC )
GO:0016787 ; hydrolase activity ( cobC )
GO:0043755 ; alpha-ribazole phosphatase activity ( cobC )
 PID 1786857  
 EC number
  (KEGG Pathway)   		 
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) COBC_ECOLI ( P52086 ; P77109 )
    -  Protein name Alpha-ribazole phosphatase  
    -  Synonyms EC 3.1.3.73, Alpha-ribazole-5'-phosphate phosphatase  
    -  Gene name Name=cobC; Synonyms=phpB; OrderedLocusNames=b0638;  

 Linear View (Whole Mode)
View Location
   660.0  –  685.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP cobC (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Structure Of Phosphoglycerate Mutase From Plasmodium Falciparum At 2.6 Resolution  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Alpha-ribazole phosphatase  
         PSI-BLAST 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
    nr     (database updated : 2007.02.20 )
         BLAST putative cobalamin synthesis protein [Escherichia coli]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    MYRISTYL    PG_MUTASE     

Other Cross-Reference
    COG COG0406G 
    EcoCyc cobC 

Sequences
Amino acid
FASTA format 
0001 MRLWLIRHGE TQANIDGLYS GHAPTPLTAR GIEQAQNLHT LLHGVSFDLV LCSELERAQH TARLVLSDRQ 
0071 LPVQIIPELN EMFFGDWEMR HHRDLMQEDA ENYSAWCNDW QHAIPTNGEG FQAFSQRVER FIARLSEFQH 
0141 YQNILVVSHQ GVLSLLIARL IGMPAEAMWH FRVDQGCWSA IDINQKFATL RVLNSRAIGV ENA
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             aaaacggtga atcatgtgag gatttattgc 
-070 cggaaccggt actgacttac attaaccaac aaggcttgta tcgctgatac ctgtcgttac ggagggcatg 
0001 atgcgactgt ggttaattcg tcatggtgaa acgcaagcga atatcgatgg tctttacagc ggtcatgcgc 
0071 ccacccccct gaccgcgcgc ggtattgagc aagcgcaaaa tctgcatacg ctgctacatg gtgtttcctt 
0141 tgatctggtt ttatgcagtg aactggaacg ggcacagcat accgcgcgac tggttctcag tgaccgccag 
0211 ctccccgtgc aaatcatacc tgaactcaac gaaatgtttt ttggcgactg ggagatgcga catcatcgcg 
0281 acctcatgca agaagatgcc gaaaactata gcgcgtggtg caatgactgg cagcatgcaa tccccacgaa 
0351 cggtgaagga tttcaggcat tttcgcaacg tgtggaacgc tttatcgcaa ggcttagtga atttcagcac 
0421 tatcagaata ttttagtcgt cagccatcag ggtgtactga gtctgttaat cgcccgttta attggcatgc 
0491 ctgccgaagc tatgtggcat tttcgcgttg accaggggtg ttggagcgcc attgatatca accaaaaatt 
0561 cgcgacgcta cgcgtcctca atagccgtgc catcggggtc gagaatgcat gacttttctg tttttttacg 
0631 ggtaagccgc aacgaccatt gacagacccg ggcaggctga tattctccgc agccagactt tttccgccag 
0701 acacgacttt gt