分離済み変異体

tm849

Allele Nametm849
Allele Type通常株
Sequence NameC48B6.6
Gene Namesmg-1
Worm BaseAllele Name tm849
Gene Name smg-1
Sequence C48B6.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" Homozygous viable. Dr. J. Kaplan: type movement, nonEgl.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 21010/21011-21535/21536 (525 bp deletion)
ChromosomeI
Putative gene structurecomplement(join(14982..15059, 15139..15272, 15317..15414, 15488..15568, 15689..15849, 15925..16012, 16090..16442, 16547..16843, 16892..16996, 17083..17320, 17421..17569, 17615..17698, 17941..18111, 18156..18440, 18487..18665, 19214..19334, 19388..19532, 19578..19873, 19977..20122, 20169..20453, 20549..20814, 21006..21146, 21219..21328, 21376..21463, 21514..21743, 21825..21932, 21974..22197, 22272..22474, 22520..22647))
Map position1.48
Balancer
Map position of balancer
Sequence of primersIntRev:GGTTTGGCTGAATCGAGTAT,ExtRev:ACGCAGCAAGTTGTGAGGTT,IntFwd:CCATCTGGCCATTTTGAGAT,ExtFwd:GCGATTTCATATGCCCATCT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Kim EJE, Son HG, Park HH, Jung Y, Kwon S, Lee SV.
Caenorhabditis elegans algn-2 Is Critical for Longevity Conferred by Enhanced Nonsense-Mediated mRNA Decay.
iScience 2020 23(11) 101713 
[ PubMed ID = 33225240 ] [ RRC reference ]

Sakaki K, Yoshina S, Shen X, Han J, DeSantis MR, Xiong M, Mitani S, Kaufman RJ.
RNA surveillance is required for endoplasmic reticulum homeostasis.
Proc Natl Acad Sci U S A 2012 109(21) 8079-84 
[ PubMed ID = 22562797 ] [ RRC reference ]