Mutants (Isolated)

tm592

Allele Name

tm592

Sequence Name

F57C9.4

CGC Name

F57C9.4

Worm Base

Allele Name

tm592

CGC Name

F57C9.4

Sequence

F57C9.4

Phenotype

homozygous viable. Dr. A. Dernburg: No defects in growth, fertility or meiotic chromosome behavior.

Mutation site

13135/13136-14085/14086 (950 bp deletion)

Chromosome

Putative gene structure

join(8317..8433, 8487..8777, 8823..8900, 9410..9689, 10006..10173, 10222..10322, 10371..10484, 10531..10782, 10826..10937, 10989..11061, 11111..11218, 11647..11820, 11868..11911, 12125..12211, 12259..12577, 13032..13122, 13545..13706)

Map position

-0.72

Balancer

Map position of balancer

Sequence of primers

ExtFwd:GCATGCGAGCATTGCGGCAA,IntFwd:CAAACGAGGACGTCGGAATT,IntRev:CAATCTACAGATGAGTGCGT,ExtRev:TGTGAAAACCCTGAGAGCCA

Distributed lab

Depositor

Dr. S. Mitani

References

Please submit your publication

Barrett A, Hermann GJ.
A Caenorhabditis elegans Homologue of LYST Functions in Endosome and Lysosome-Related Organelle Biogenesis.
Traffic 2016 17(5) 515-35
[ PubMed ID = 26822177 ] [ RRC reference ]

Sato K, Norris A, Sato M, Grant BD.
C. elegans as a model for membrane traffic.
WormBook 2014 1-47
[ PubMed ID = 24778088 ] [ RRC reference ]

Morris C, Foster OK, Handa S, Peloza K, Voss L, Somhegyi H, Jian Y, Vo MV, Harp M, Rambo FM, Yang C, Hermann GJ.
Function and regulation of the Caenorhabditis elegans Rab32 family member GLO-1 in lysosome-related organelle biogenesis.
PLoS Genet 2018 14(11) e1007772
[ PubMed ID = 30419011 ] [ RRC reference ]

Hermann GJ, Scavarda E, Weis AM, Saxton DS, Thomas LL, Salesky R, Somhegyi H, Curtin TP, Barrett A, Foster OK, Vine A, Erlich K, Kwan E, Rabbitts BM, Warren K.
C. elegans BLOC-1 functions in trafficking to lysosome-related gut granules.
PLoS One 2012 7(8) e43043
[ PubMed ID = 22916203 ] [ RRC reference ]

Delahaye JL, Foster OK, Vine A, Saxton DS, Curtin TP, Somhegyi H, Salesky R, Hermann GJ.
Caenorhabditis elegans HOPS and CCZ-1 mediate trafficking to lysosome-related organelles independently of RAB-7 and SAND-1.
Mol Biol Cell 2014 25(7) 1073-96
[ PubMed ID = 24501423 ] [ RRC reference ]