Home > 分離済み変異体 > tm5356

分離済み変異体

Allele Name		tm5356
Balance		Not Required
OutCross		Not Accepted
Sequence Name		F25H2.2
Gene Name		F25H2.2
Worm Base	Allele Name	tm5356
	Gene Name	F25H2.2
	Sequence	F25H2.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		9247/9248-9789/9790 (542 bp deletion)
Chromosome		I
Putative gene structure		join(9119..9191, 9465..9952, 10448..10877, 11165..11556, 11601..11762, 12087..12278)
Map position		5.07
Balancer
Map position of balancer
Sequence of primers		ExtFwd:TATTCCCCCCATATCCAGTC,ExtRev:TCGTAGACTTACCGTATACC,IntFwd:GCCGTTCGATGATTTATGTG,IntRev:CCATATGCCATTGAACTCTC
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Armada G, Roque S, Serre-Miranda C, Ferreira L, Vale A, Rodrigues AJ, Hong W, Correia-Neves M, Vieira N. SNX27: A trans-species cognitive modulator with implications for anxiety and stress susceptibility. Neurobiol Stress 2024 30 100619  [ PubMed ID = 38500791 ] [ RRC reference ] Tian Y, Kang Q, Shi X, Wang Y, Zhang N, Ye H, Xu Q, Xu T, Zhang R. SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking. PLoS Genet 2021 17(6) e1009607  [ PubMed ID = 34081703 ] [ RRC reference ] McGough IJ, de Groot REA, Jellett AP, Betist MC, Varandas KC, Danson CM, Heesom KJ, Korswagen HC, Cullen PJ. SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion. Nat Commun 2018 9(1) 3737  [ PubMed ID = 30213940 ] [ RRC reference ] Vieira N, Bessa C, Rodrigues AJ, Marques P, Chan FY, de Carvalho AX, Correia-Neves M, Sousa N. Sorting nexin 3 mutation impairs development and neuronal function in Caenorhabditis elegans. Cell Mol Life Sci 2018 75(11) 2027-2044  [ PubMed ID = 29196797 ] [ RRC reference ] Gleason RJ, Akintobi AM, Grant BD, Padgett RW. BMP signaling requires retromer-dependent recycling of the type I receptor. Proc Natl Acad Sci U S A 2014 111(7) 2578-83  [ PubMed ID = 24550286 ] [ RRC reference ]