分離済み変異体

tm5202

Allele Nametm5202
BalanceNot Required
OutCrossNot Accepted
Sequence NameC34B7.2
Gene NameC34B7.2
Worm BaseAllele Name tm5202
Gene Name C34B7.2
Sequence C34B7.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 7566/7567-7802/7803 (236 bp deletion)
ChromosomeI
Putative gene structurejoin(7072..7276, 7699..7811, 7865..8127, 8651..9665, 9725..10264, 11137..11595, 11649..11771)
Map position2.74
Balancer
Map position of balancer
Sequence of primersIntRev:CATCTGCTTCCAGTCGTCTC,ExtRev:AGTGTCCCTTAAAGGCGCAC,IntFwd:GACGACGCACCAAAAATACT,ExtFwd:CTATAAATCTCACACGCCGT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Eck RJ, Stair JG, Kraemer BC, Liachko NF.
Simple models to understand complex disease: 10 years of progress from Caenorhabditis elegans models of amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
Front Neurosci 2023 17 1300705 
[ PubMed ID = 38239833 ] [ RRC reference ]

Osborne JF, Yanagi KS, Hart AC.
Genetic interactions in a C. elegans sod-1 ALS model: glutamatergic neuron degeneration.
MicroPubl Biol 2021 2021  
[ PubMed ID = 33474528 ] [ RRC reference ]

Liu K, Jian Y, Sun X, Yang C, Gao Z, Zhang Z, Liu X, Li Y, Xu J, Jing Y, Mitani S, He S, Yang C.
Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion.
J Cell Biol 2016 212(2) 181-98 
[ PubMed ID = 26783301 ] [ RRC reference ]