分離済み変異体

tm4853

Allele Nametm4853
BalanceNot Required
OutCrossNot Accepted
Sequence NameC36A4.9
Gene Nameacs-19
Worm BaseAllele Name tm4853
Gene Name acs-19
Sequence C36A4.9
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 36972/36973-37442/37443 (470 bp deletion)
ChromosomeIII
Putative gene structurejoin(35919..35978, 36029..36739, 36864..36979, 37038..37364, 37416..38244)
Map position-42.5
Balancer
Map position of balancer
Sequence of primersIntRev:GTCTGGCACCATCTCCAGTG,ExtRev:CGTCCAGTTATCCACAAGTA,IntFwd:ACCTAGCCAACGATGGAGAA,ExtFwd:CATGTCGGACGTTCGCGTCA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Ruan M, Xu F, Li N, Yu J, Teng F, Tang J, Huang C, Zhu H.
Free long-chain fatty acids trigger early postembryonic development in starved Caenorhabditis elegans by suppressing mTORC1.
PLoS Biol 2024 22(10) e3002841 
[ PubMed ID = 39436954 ] [ RRC reference ]

Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Segref A, Kevei É, Pokrzywa W, Schmeisser K, Mansfeld J, Livnat-Levanon N, Ensenauer R, Glickman MH, Ristow M, Hoppe T.
Pathogenesis of human mitochondrial diseases is modulated by reduced activity of the ubiquitin/proteasome system.
Cell Metab 2014 19(4) 642-52 
[ PubMed ID = 24703696 ] [ RRC reference ]