Home > 分離済み変異体 > tm4566

分離済み変異体

Allele Name		tm4566
Allele Type		バランス済
Sequence Name		F02E9.2
Gene Name		lin-28
Worm Base	Allele Name	tm4566
	Gene Name	lin-28
	Sequence	F02E9.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		Let or Ste.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		4615/4616-AAAA-4948/4949 (333 bp deletion + 4 bp insertion)
Chromosome		I
Putative gene structure		complement(join(3766..4101, 4739..4945, 6268..6408))
Map position		2.79
Balancer		hT2
Map position of balancer
Sequence of primers		ExtRev:CCGGTGCCCATCAAATCTCA,IntFwd:CGGATTCCCGTATCTCAATA,ExtFwd:CCCCTAAATCGACACAGCTA,IntRev:TTCCAGTGACGATTCGGGGT
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Cao W, Fan Q, Amparado G, Begic D, Godini R, Gopal S, Pocock R. A nucleic acid binding protein map of germline regulation in Caenorhabditis elegans. Nat Commun 2024 15(1) 6884  [ PubMed ID = 39128930 ] [ RRC reference ] Wang D, Hou L, Nakamura S, Su M, Li F, Chen W, Yan Y, Green CD, Chen D, Zhang H, Antebi A, Han JJ. LIN-28 balances longevity and germline stem cell number in Caenorhabditis elegans through let-7/AKT/DAF-16 axis. Aging Cell 2017 16(1) 113-124  [ PubMed ID = 27730721 ] [ RRC reference ] Zinovyeva AY, Bouasker S, Simard MJ, Hammell CM, Ambros V. Mutations in conserved residues of the C. elegans microRNA Argonaute ALG-1 identify separable functions in ALG-1 miRISC loading and target repression. PLoS Genet 2014 10(4) e1004286  [ PubMed ID = 24763381 ] [ RRC reference ]