分離済み変異体

tm402

Allele Nametm402
BalanceCompleted
OutCrossNot Accepted
Sequence NameC35B8.2
Gene Namevav-1
Worm BaseAllele Name tm402 (x1)
Gene Name vav-1
Sequence C35B8.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Er. V. Maricq: L1 lethal that has a severe pharyngeal pumping defects.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 21310/21311-22783/22784 (1473 bp deletion)
ChromosomeX
Putative gene structurecomplement(join(17370..17471, 17567..17657, 17701..17949, 18248..18357, 19218..19405, 20149..20297, 20344..20921, 21020..21224, 21534..21844, 22331..22412, 22480..22620, 22752..22927, 22981..23071, 23321..23430))
Map position1.05
Balancer,szT1[umnIs40]
Map position of balancer
Sequence of primersIntFwd:CCGGAAAGAATGAAATGCCA,ExtRev:GCATTTTCAGGTGCCCATGA,ExtFwd:GTTGCTGGATTCTTAACGTC,IntRev:ATTGGGTGCGCCCGATGGTT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Norman KR, Fazzio RT, Mellem JE, Espelt MV, Strange K, Beckerle MC, Maricq AV.
The Rho/Rac-family guanine nucleotide exchange factor VAV-1 regulates rhythmic behaviors in C. elegans.
Cell 2005 123(1) 119-32 
[ PubMed ID = 16213217 ] [ RRC reference ]