分離済み変異体

tm3647

Allele Nametm3647
BalanceNot Required
OutCrossNot Accepted
Sequence NameY71H2AM.17
Gene NameY71H2AM.17
Worm BaseAllele Name tm3647
Gene Name Y71H2AM.17
Sequence Y71H2AM.17
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. H. Sawa: non Psa.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 76985/76986-AAA-77417/77418 (432 bp deletion + 3 bp insertion)
ChromosomeIII
Putative gene structurecomplement(join(73322..73539, 74803..75005, 75640..75675, 75825..75913, 76685..76876, 76926..76991, 77037..77243, 77296..77337))
Map position-11.17
Balancer
Map position of balancer
Sequence of primersIntRev:CCCACTGGACATTGAGGGGA,IntFwd:TAACGATGCTCGGCGAGAAC,ExtRev:CACGTGCCAGGCTTGCCAAA,ExtFwd:CATTCGGTGGTGTGGAACTA
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Flibotte S, Kim BR, Van de Laar E, Brown L, Moghal N.
The SWI/SNF chromatin remodeling complex exerts both negative and positive control over LET-23/EGFR-dependent vulval induction in Caenorhabditis elegans.
Dev Biol 2016 415(1) 46-63 
[ PubMed ID = 27207389 ] [ RRC reference ]

Mathies LD, Blackwell GG, Austin MK, Edwards AC, Riley BP, Davies AG, Bettinger JC.
SWI/SNF chromatin remodeling regulates alcohol response behaviors in Caenorhabditis elegans and is associated with alcohol dependence in humans.
Proc Natl Acad Sci U S A 2015 112(10) 3032-7 
[ PubMed ID = 25713357 ] [ RRC reference ]

Large EE, Mathies LD.
Caenorhabditis elegans SWI/SNF subunits control sequential developmental stages in the somatic gonad.
G3 (Bethesda) 2014 4(3) 471-83 
[ PubMed ID = 24402584 ] [ RRC reference ]

Riedel CG, Dowen RH, Lourenco GF, Kirienko NV, Heimbucher T, West JA, Bowman SK, Kingston RE, Dillin A, Asara JM, Ruvkun G.
DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity.
Nat Cell Biol 2013 15(5) 491-501 
[ PubMed ID = 23604319 ] [ RRC reference ]