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分離済み変異体

Allele Name		tm3302
Balance		Not Required
OutCross		Not Accepted
Sequence Name		F11E6.1
Gene Name		gba-3
Worm Base	Allele Name	tm3302
	Gene Name	gba-3
	Sequence	F11E6.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		35535/35536-CATTGAGGCCACA-35826/35827 (291 bp deletion + 13 bp insertion)
Chromosome		IV
Putative gene structure		join(34673..34727, 35125..35334, 35401..35684, 35734..35900, 5949..36324, 36871..36958, AL031254.1:71..230, L031254.1:273..501)
Map position		17.16
Balancer
Map position of balancer
Sequence of primers		ExtFwd:TTTAGGTGTGGGGAGGTAGT,IntFwd:ACCTATGACGGCGCGTTTCT,ExtRev:TCAGCCCATCCAGGGAGTAA,IntRev:CATAGTCTGCCATCTCCATG
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Liu N, Li R, Huang X, Lakso M, Wong G. The C. elegans gba-3 gene encodes a glucocerebrosidase that exacerbates α-synuclein-mediated impairments in deletion mutants. Transl Neurodegener 2025 14(1) 9  [ PubMed ID = 39940047 ] [ RRC reference ] Hao L, Ben-David O, Babb SM, Futerman AH, Cohen BM, Buttner EA. Clozapine Modulates Glucosylceramide, Clears Aggregated Proteins, and Enhances ATG8/LC3 in Caenorhabditis elegans. Neuropsychopharmacology 2017 42(4) 951-962  [ PubMed ID = 27711049 ] [ RRC reference ]