Home > 分離済み変異体 > tm3117

分離済み変異体

Allele Name		tm3117
Allele Type		通常株
Sequence Name		Y49E10.11
Gene Name		tat-1
Worm Base	Allele Name	tm3117
	Gene Name	tat-1
	Sequence	Y49E10.11
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		50225/50226-50592/50593 (367 bp deletion)
Chromosome		III
Putative gene structure		complement(join(31959..32056, 32642..32766, 37381..37473, 38318..38574, 39898..40038, 40248..40381, 40524..40678, 42286..42815, 44720..45258, 46349..46649, 47456..47568, 48159..48398, 50066..50372, 51442..51627, 52670..52769, 52820..52877, 53218..53260))
Map position		17.57
Balancer
Map position of balancer
Sequence of primers		ExtFwd:AAAGCAGCTGATCAATACCG,IntFwd:TCAATACCGAAATGTCTGGC,ExtRev:TCCCCACACAGAGTGTAGTC,IntRev:GACGTTAGCCCGACTGGAAG
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Chen YZ, Klöditz K, Lee ES, Nguyen DP, Yuan Q, Johnson J, Lee-Yow Y, Hall A, Mitani S, Xia NS, Fadeel B, Xue D. Structure and function analysis of the C. elegans aminophospholipid translocase TAT-1. J Cell Sci 2019 132(5)   [ PubMed ID = 30683797 ] [ RRC reference ] Nichols ALA, Meelkop E, Linton C, Giordano-Santini R, Sullivan RK, Donato A, Nolan C, Hall DH, Xue D, Neumann B, Hilliard MA. The Apoptotic Engulfment Machinery Regulates Axonal Degeneration in C. elegans Neurons. Cell Rep 2016 14(7) 1673-1683  [ PubMed ID = 26876181 ] [ RRC reference ] Mapes J, Chen YZ, Kim A, Mitani S, Kang BH, Xue D. CED-1, CED-7, and TTR-52 regulate surface phosphatidylserine expression on apoptotic and phagocytic cells. Curr Biol 2012 22(14) 1267-75  [ PubMed ID = 22727702 ] [ RRC reference ] Chen YZ, Mapes J, Lee ES, Skeen-Gaar RR, Xue D. Caspase-mediated activation of Caenorhabditis elegans CED-8 promotes apoptosis and phosphatidylserine externalization. Nat Commun 2013 4 2726  [ PubMed ID = 24225442 ] [ RRC reference ]