Home > 分離済み変異体 > tm3042

分離済み変異体

Allele Name		tm3042
Balance		Completed
OutCross		Not Accepted
Sequence Name		W03H9.4
Gene Name		cacn-1
Worm Base	Allele Name	tm3042 (x1)
	Gene Name	cacn-1
	Sequence	W03H9.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile. Dr. E. Cram: L1-L2 arrest, Mlt.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		53/54-235/236 (182 bp deletion)
Chromosome		II
Putative gene structure		complement(join(29517..30017, 31189..31570, 32474..32931, 36350..36549, 37488..[W03H9]112, 200..547, 600..644))
Map position		22.45
Balancer		,mnC1 [dpy-10(e128) unc52(e444) nIs190 let-?]
Map position of balancer
Sequence of primers		IntRev:CGGCTTGCCGAGCAAAGATC,ExtRev:AGAGATCGCCTTCAACGTCC,IntFwd:CGCCGTATGTGGATTCTCGT,ExtFwd:TCGGGAATTTTCGCCGTATG
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Mazzetto M, Gonzalez LE, Sanchez N, Reinke V. Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis. Genome Res 2024 34(1) 57-69  [ PubMed ID = 38164610 ] [ RRC reference ] Cecchetelli AD, Hugunin J, Tannoury H, Cram EJ. CACN-1 is required in the Caenorhabditis elegans somatic gonad for proper oocyte development. Dev Biol 2016 414(1) 58-71  [ PubMed ID = 27046631 ] [ RRC reference ] LaBonty M, Szmygiel C, Byrnes LE, Hughes S, Woollard A, Cram EJ. CACN-1/Cactin plays a role in Wnt signaling in C. elegans. PLoS One 2014 9(7) e101945  [ PubMed ID = 24999833 ] [ RRC reference ] Matus DQ, Li XY, Durbin S, Agarwal D, Chi Q, Weiss SJ, Sherwood DR. In vivo identification of regulators of cell invasion across basement membranes. Sci Signal 2010 3(120) ra35  [ PubMed ID = 20442418 ] [ RRC reference ] Tannoury H, Rodriguez V, Kovacevic I, Ibourk M, Lee M, Cram EJ. CACN-1/Cactin interacts genetically with MIG-2 GTPase signaling to control distal tip cell migration in C. elegans. Dev Biol 2010 341(1) 176-85  [ PubMed ID = 20188721 ] [ RRC reference ]