分離済み変異体

tm2943

Allele Nametm2943
Allele Type通常株
Sequence NameT24A6.5
Gene Namesrbc-66
Worm BaseAllele Name tm2943
Gene Name srbc-66
Sequence T24A6.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 5667/5668-5960/5961 (293 bp deletion)
ChromosomeV
Putative gene structurejoin(5633..5807, 5999..6456, 7083..7310)
Map position-9.95
Balancer
Map position of balancer
Sequence of primersExtFwd:TCCCACCTGACTTGTTAGTC,ExtRev:GGGTGCTGCGAAACATGCAC,IntFwd:AACCCCATCAGCTAATACGA,IntRev:ATTCGCATGAATCGCCACAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Peng JY, Liu X, Zeng XT, Hao Y, Zhang JH, Li Q, Tong XJ.
Early pheromone perception remodels neurodevelopment and accelerates neurodegeneration in adult C. elegans.
Cell Rep 2023 42(6) 112598 
[ PubMed ID = 37289584 ] [ RRC reference ]

Park JY, Joo HJ, Park S, Paik YK.
Ascaroside Pheromones: Chemical Biology and Pleiotropic Neuronal Functions.
Int J Mol Sci 2019 20(16)  
[ PubMed ID = 31405082 ] [ RRC reference ]

Park J, Choi W, Dar AR, Butcher RA, Kim K.
Neuropeptide Signaling Regulates Pheromone-Mediated Gene Expression of a Chemoreceptor Gene in C. elegans.
Mol Cells 2019 42(1) 28-35 
[ PubMed ID = 30453729 ] [ RRC reference ]

Reis Rodrigues P, Kaul TK, Ho JH, Lucanic M, Burkewitz K, Mair WB, Held JM, Bohn LM, Gill MS.
Synthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans.
G3 (Bethesda) 2016 6(6) 1695-705 
[ PubMed ID = 27172180 ] [ RRC reference ]

Neal SJ, Park J, DiTirro D, Yoon J, Shibuya M, Choi W, Schroeder FC, Butcher RA, Kim K, Sengupta P.
A Forward Genetic Screen for Molecules Involved in Pheromone-Induced Dauer Formation in Caenorhabditis elegans.
G3 (Bethesda) 2016 6(5) 1475-87 
[ PubMed ID = 26976437 ] [ RRC reference ]

Zhou Y, Loeza-Cabrera M, Liu Z, Aleman-Meza B, Nguyen JK, Jung SK, Choi Y, Shou Q, Butcher RA, Zhong W.
Potential Nematode Alarm Pheromone Induces Acute Avoidance in Caenorhabditis elegans.
Genetics 2017 206(3) 1469-1478 
[ PubMed ID = 28495959 ] [ RRC reference ]

Yamada K, Hirotsu T, Matsuki M, Butcher RA, Tomioka M, Ishihara T, Clardy J, Kunitomo H, Iino Y.
Olfactory plasticity is regulated by pheromonal signaling in Caenorhabditis elegans.
Science 2010 329(5999) 1647-50 
[ PubMed ID = 20929849 ] [ RRC reference ]

Kim K, Sato K, Shibuya M, Zeiger DM, Butcher RA, Ragains JR, Clardy J, Touhara K, Sengupta P.
Two chemoreceptors mediate developmental effects of dauer pheromone in C. elegans.
Science 2009 326(5955) 994-8 
[ PubMed ID = 19797623 ] [ RRC reference ]