分離済み変異体

tm2895

Allele Nametm2895
Allele Type通常株
Sequence NameR05H10.5
Gene NameR05H10.5
Worm BaseAllele Name tm2895
Gene Name R05H10.5
Sequence R05H10.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 40879/40880-41386/41387 (507 bp deletion)
ChromosomeIII
Putative gene structurejoin(40653..40720, 40819..40905, 41670..42006)
Map position-0.79
Balancer
Map position of balancer
Sequence of primersIntFwd:CTCTCAACCGCATCCGCAAT,ExtFwd:CGCTCGTCGTTTCATCTCAC,IntRev:ACGGGAATGCGAGAACTTCG,ExtRev:TGATGGTTCCTGACCACCGA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Schiavi A, Salveridou E, Brinkmann V, Shaik A, Menzel R, Kalyanasundaram S, Nygård S, Nilsen H, Ventura N.
Mitochondria hormesis delays aging and associated diseases in Caenorhabditis elegans impacting on key ferroptosis players.
iScience 2023 26(4) 106448 
[ PubMed ID = 37020951 ] [ RRC reference ]

Tsai Y, Lin YC, Lee YH.
Octopamine-MAPK-SKN-1 signaling suppresses mating-induced oxidative stress in Caenorhabditis elegans gonads to protect fertility.
iScience 2023 26(3) 106162 
[ PubMed ID = 36876134 ] [ RRC reference ]

Sakamoto T, Maebayashi K, Tsunoda Y, Imai H.
Inhibition of lipid peroxidation during the reproductive period extends the lifespan of Caenorhabditis elegans.
J Clin Biochem Nutr 2020 66(2) 116-123 
[ PubMed ID = 32231407 ] [ RRC reference ]

Sakamoto T, Maebayashi K, Nakagawa Y, Imai H.
Deletion of the four phospholipid hydroperoxide glutathione peroxidase genes accelerates aging in Caenorhabditis elegans.
Genes Cells 2014 19(10) 778-92 
[ PubMed ID = 25200408 ] [ RRC reference ]

Song S, Zhang X, Wu H, Han Y, Zhang J, Ma E, Guo Y.
Molecular basis for antioxidant enzymes in mediating copper detoxification in the nematode Caenorhabditis elegans.
PLoS One 2014 9(9) e107685 
[ PubMed ID = 25243607 ] [ RRC reference ]

Erkut C, Vasilj A, Boland S, Habermann B, Shevchenko A, Kurzchalia TV.
Molecular strategies of the Caenorhabditis elegans dauer larva to survive extreme desiccation.
PLoS One 2013 8(12) e82473 
[ PubMed ID = 24324795 ] [ RRC reference ]