分離済み変異体

tm284

Allele Name

tm284

Balance

Not Required

OutCross

Not Accepted

Sequence Name

F31A3.4

Gene Name

hlh-29

Worm Base

Allele Name

tm284

Gene Name

hlh-29

Sequence

F31A3.4

Phenotype

homozygous viable. Dr. R. Lin, Dr. M. Maduro: normal cell division during 8-30 cell stage. Dr. P. Sengupta: normal dye-filling into sensory neurons. Dr. J. Priess: Dev. Cell 8, 867-879 (2005). Dr. O. Hobert: ASE & AIY fate markers normal. Dr. C.M. Johnson: BBA 1769, 5 (2007).

Mutation site

15502/15503-17344/17345 (1842 bp deletion)

Chromosome

Putative gene structure

complement(join(16105..16429, 16479..16703, 16756..16925))

Map position

24.06

Balancer

Map position of balancer

Sequence of primers

ExtFwd:TACACAGCGATCCAGCATTT,IntFwd:CCGTTGCTACCTTAGAAATG,IntRev:GGCATAGGATCACAAAAAGG,ExtRev:CGTCTATTTAACTCCGCCTA

Distributed lab

Depositor

Dr. S. Mitani

References

Please submit your publication

Quach TK, Chou HT, Wang K, Milledge GZ, Johnson CM.
Genome-wide microarrray analysis reveals roles for the REF-1 family member HLH-29 in ferritin synthesis and peroxide stress response.
PLoS One 2013 8(3) e59719
[ PubMed ID = 23533643 ] [ RRC reference ]

White A, Fearon A, Johnson CM.
HLH-29 regulates ovulation in C. elegans by targeting genes in the inositol triphosphate signaling pathway.
Biol Open 2012 1(3) 261-8
[ PubMed ID = 23213416 ] [ RRC reference ]

McMiller TL, Sims D, Lee T, Williams T, Johnson CM.
Molecular characterization of the Caenorhabditis elegans REF-1 family member, hlh-29/hlh-28.
Biochim Biophys Acta 2007 1769(1) 5-19
[ PubMed ID = 17258327 ] [ RRC reference ]

Lanjuin A, Claggett J, Shibuya M, Hunter CP, Sengupta P.
Regulation of neuronal lineage decisions by the HES-related bHLH protein REF-1.
Dev Biol 2006 290(1) 139-51
[ PubMed ID = 16376329 ] [ RRC reference ]

Neves A, Priess JR.
The REF-1 family of bHLH transcription factors pattern C. elegans embryos through Notch-dependent and Notch-independent pathways.
Dev Cell 2005 8(6) 867-79
[ PubMed ID = 15935776 ] [ RRC reference ]