Mutants (Isolated)


Allele Nametm284
Sequence NameF31A3.4
CGC Namehlh-29
Worm BaseAllele Name tm284
CGC Name hlh-29
Sequence F31A3.4
Phenotypehomozygous viable. Dr. R. Lin, Dr. M. Maduro: normal cell division during 8-30 cell stage. Dr. P. Sengupta: normal dye-filling into sensory neurons. Dr. J. Priess: Dev. Cell 8, 867-879 (2005). Dr. O. Hobert: ASE & AIY fate markers normal. Dr. C.M. Johnson: BBA 1769, 5 (2007).
Mutation site15502/15503-17344/17345 (1842 bp deletion)
Putative gene structurecomplement(join(16105..16429, 16479..16703, 16756..16925))
Map position24.06
Map position of balancer
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Quach TK, Chou HT, Wang K, Milledge GZ, Johnson CM.
Genome-wide microarrray analysis reveals roles for the REF-1 family member HLH-29 in ferritin synthesis and peroxide stress response.
PLoS ONE 2013 8(3) e59719 
[ PubMed ID = 23533643 ] [ RRC reference ]

White A, Fearon A, Johnson CM.
HLH-29 regulates ovulation in C. elegans by targeting genes in the inositol triphosphate signaling pathway.
Biol Open 2012 1(3) 261-8 
[ PubMed ID = 23213416 ] [ RRC reference ]

Lanjuin A, Claggett J, Shibuya M, Hunter CP, Sengupta P.
Regulation of neuronal lineage decisions by the HES-related bHLH protein REF-1.
Dev. Biol. 2006 290(1) 139-51 
[ PubMed ID = 16376329 ] [ RRC reference ]

McMiller TL, Sims D, Lee T, Williams T, Johnson CM.
Molecular characterization of the Caenorhabditis elegans REF-1 family member, hlh-29/hlh-28.
Biochim. Biophys. Acta 2007 1769(1) 5-19 
[ PubMed ID = 17258327 ] [ RRC reference ]

Neves A, Priess JR.
The REF-1 family of bHLH transcription factors pattern C. elegans embryos through Notch-dependent and Notch-independent pathways.
Dev. Cell 2005 8(6) 867-79 
[ PubMed ID = 15935776 ] [ RRC reference ]