Mutants (Isolated)

tm2669

Allele Name

tm2669

Sequence Name

AH6.1

CGC Name

gcy-1

Worm Base

Allele Name

tm2669

CGC Name

gcy-1

Sequence

AH6.1

Phenotype

homozygous viable. Dr. O. Hobert: potassium chemotaxis defective.

Mutation site

2666/2667-3349/3350 (683 bp deletion)

Chromosome

Putative gene structure

complement(join(4270..4368, 3996..4126, 3469..3711, 3195..3424, 2999..3151, 2851..2948, 2672..2797, 2483..2621, 2288..2418, 1579..2235, 1226..1526, 1002..1179, 544..951, 397..500, 102..337, Z48007.1:14051..14230))

Map position

1.48

Balancer

Map position of balancer

Sequence of primers

ExtFwd:GTTACTCCACTGTGCCCAGT,IntFwd:GATCTCCGACTTGCCCCTTT,ExtRev:ATCGGACCACCATGCGCACA,IntRev:ATGTCATACGATTTCCGCAC

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Hallem EA, Spencer WC, McWhirter RD, Zeller G, Henz SR, Rätsch G, Miller DM 3rd, Horvitz HR, Sternberg PW, Ringstad N.
Receptor-type guanylate cyclase is required for carbon dioxide sensation by Caenorhabditis elegans.
Proc Natl Acad Sci U S A 2011 108(1) 254-9
[ PubMed ID = 21173231 ] [ RRC reference ]

Mok CA, Healey MP, Shekhar T, Leroux MR, Héon E, Zhen M.
Mutations in a guanylate cyclase GCY-35/GCY-36 modify Bardet-Biedl syndrome-associated phenotypes in Caenorhabditis elegans.
PLoS Genet 2011 7(10) e1002335
[ PubMed ID = 22022287 ] [ RRC reference ]

Smith HK, Luo L, O'Halloran D, Guo D, Huang XY, Samuel AD, Hobert O.
Defining specificity determinants of cGMP mediated gustatory sensory transduction in Caenorhabditis elegans.
Genetics 2013 194(4) 885-901
[ PubMed ID = 23695300 ] [ RRC reference ]

Murayama T, Takayama J, Fujiwara M, Maruyama IN.
Environmental alkalinity sensing mediated by the transmembrane guanylyl cyclase GCY-14 in C. elegans.
Curr Biol 2013 23(11) 1007-12
[ PubMed ID = 23664973 ] [ RRC reference ]

Ortiz CO, Faumont S, Takayama J, Ahmed HK, Goldsmith AD, Pocock R, McCormick KE, Kunimoto H, Iino Y, Lockery S, Hobert O.
Lateralized gustatory behavior of C. elegans is controlled by specific receptor-type guanylyl cyclases.
Curr Biol 2009 19(12) 996-1004
[ PubMed ID = 19523832 ] [ RRC reference ]