分離済み変異体

tm2639

Allele Nametm2639
BalanceNot Required
OutCrossNot Accepted
Sequence NameT05C12.6
Gene Namemig-5
Worm BaseAllele Name tm2639
Gene Name mig-5
Sequence T05C12.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. H. Sawa: QL cell migration abonormal, some animals have one or no gonadal arms, not Psa.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 15686/15687-ATATT-16497/16498 (811 bp deletion + 5 bp insertion)
ChromosomeII
Putative gene structurecomplement(join(14324..14472, 14636..15160, 15209..15534, 15581..15703, 15746..16223, 16276..16351, 16393..16546, 16601..16749, 16816..16854))
Map position0.75
Balancer
Map position of balancer
Sequence of primersExtRev:ACCCGGATATTCAACGGTGA,IntRev:TGATTCGGATCGGCTGCGCA,ExtFwd:GTGTCCGTGGAATTACGATC,IntFwd:CTTGCTGACGACATGTCTGA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Riva C, Hajduskova M, Gally C, Suman SK, Ahier A, Jarriault S.
A natural transdifferentiation event involving mitosis is empowered by integrating signaling inputs with conserved plasticity factors.
Cell Rep 2022 40(12) 111365 
[ PubMed ID = 36130499 ] [ RRC reference ]

Lu M, Mizumoto K.
Gradient-independent Wnt signaling instructs asymmetric neurite pruning in C. elegans.
Elife 2019 8  
[ PubMed ID = 31804181 ] [ RRC reference ]

Baldwin AT, Clemons AM, Phillips BT.
Unique and redundant β-catenin regulatory roles of two Dishevelled paralogs during C. elegans asymmetric cell division.
J Cell Sci 2016 129(5) 983-93 
[ PubMed ID = 26795562 ] [ RRC reference ]

Sanchez-Alvarez L, Visanuvimol J, McEwan A, Su A, Imai JH, Colavita A.
VANG-1 and PRKL-1 cooperate to negatively regulate neurite formation in Caenorhabditis elegans.
PLoS Genet 2011 7(9) e1002257 
[ PubMed ID = 21912529 ] [ RRC reference ]