Mutants (Isolated)


Allele Nametm2484
Allele TypeNormal
Sequence NameC06H5.7
Gene Namedcar-1
Worm BaseAllele Name tm2484
Gene Name dcar-1
Sequence C06H5.7
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 34337/34338-34561/34562 (224 bp deletion)
Putative gene structurejoin(30190..30258, 32442..32558, 32605..32732, 34092..34256, 34308..34643, 34836..34980, 36718..36948)
Map position13.33
Map position of balancer
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Hodgkin J.
Nematode Autotomy Requires Molting and Entails Tissue Healing without Obvious Regeneration.
J Dev Biol 2019 7(4)  
[ PubMed ID = 31771156 ] [ RRC reference ]

Aoki R, Yagami T, Sasakura H, Ogura K, Kajihara Y, Ibi M, Miyamae T, Nakamura F, Asakura T, Kanai Y, Misu Y, Iino Y, Ezcurra M, Schafer WR, Mori I, Goshima Y.
A seven-transmembrane receptor that mediates avoidance response to dihydrocaffeic acid, a water-soluble repellent in Caenorhabditis elegans.
J Neurosci 2011 31(46) 16603-10 
[ PubMed ID = 22090488 ] [ RRC reference ]

Zugasti O, Bose N, Squiban B, Belougne J, Kurz CL, Schroeder FC, Pujol N, Ewbank JJ.
Activation of a G protein-coupled receptor by its endogenous ligand triggers the innate immune response of Caenorhabditis elegans.
Nat Immunol 2014 15(9) 833-8 
[ PubMed ID = 25086774 ] [ RRC reference ]

Vérièpe J, Fossouo L, Parker JA.
Neurodegeneration in C. elegans models of ALS requires TIR-1/Sarm1 immune pathway activation in neurons.
Nat Commun 2015 6 7319 
[ PubMed ID = 26059317 ] [ RRC reference ]