Mutants (Isolated)

tm2350

Allele Name

tm2350

Sequence Name

C14C11.3

CGC Name

hex-2

Worm Base

Allele Name

tm2350

CGC Name

hex-2

Sequence

C14C11.3

Phenotype

homozygous viable. Dr. I. Wilson: J. Biol. Chem. 282, 27825 (2007).

Mutation site

13237/13238-GTGT-13704/13705 (467 bp deletion + 4 bp insertion)

Chromosome

Putative gene structure

join(11880..11930, 12328..12513, 12568..12651, 13331..13783, 13832..13962, 14461..14582, 14626..14768, 15035..15287, 15335..15542, 15816..15975)

Map position

-1.31

Balancer

Map position of balancer

Sequence of primers

ExtFwd:CACGCCTCATTTTCGATAGT,ExtRev:CATGGGGCTCCAGGTGAACT,IntFwd:AGCTTGTACTTTGAGCGTAG,IntRev:CACTGTGTAGAATCTCCGGT

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Yan S, Bleuler-Martinez S, Plaza DF, Künzler M, Aebi M, Joachim A, Razzazi-Fazeli E, Jantsch V, Geyer R, Wilson IB, Paschinger K.
Galactosylated fucose epitopes in nematodes: increased expression in a Caenorhabditis mutant associated with altered lectin sensitivity and occurrence in parasitic species.
J. Biol. Chem. 2012 287(34) 28276-90
[ PubMed ID = 22733825 ] [ RRC reference ]

Paschinger K, Gutternigg M, Rendić D, Wilson IB.
The N-glycosylation pattern of Caenorhabditis elegans.
Carbohydr. Res. 2008 343(12) 2041-9
[ PubMed ID = 18226806 ] [ RRC reference ]

Gutternigg M, Kretschmer-Lubich D, Paschinger K, Rendić D, Hader J, Geier P, Ranftl R, Jantsch V, Lochnit G, Wilson IB.
Biosynthesis of truncated N-linked oligosaccharides results from non-orthologous hexosaminidase-mediated mechanisms in nematodes, plants, and insects.
J. Biol. Chem. 2007 282(38) 27825-40
[ PubMed ID = 17636254 ] [ RRC reference ]