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Mutants (Isolated)

Allele Name		tm2350
Sequence Name		C14C11.3
CGC Name		hex-2
Worm Base	Allele Name	tm2350
	CGC Name	hex-2
	Sequence	C14C11.3
Phenotype		homozygous viable. Dr. I. Wilson: J. Biol. Chem. 282, 27825 (2007).
Mutation site		13237/13238-GTGT-13704/13705 (467 bp deletion + 4 bp insertion)
Chromosome		V
Putative gene structure		join(11880..11930, 12328..12513, 12568..12651, 13331..13783, 13832..13962, 14461..14582, 14626..14768, 15035..15287, 15335..15542, 15816..15975)
Map position		-1.31
Balancer
Map position of balancer
Sequence of primers		ExtFwd:CACGCCTCATTTTCGATAGT,ExtRev:CATGGGGCTCCAGGTGAACT,IntFwd:AGCTTGTACTTTGAGCGTAG,IntRev:CACTGTGTAGAATCTCCGGT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Yan S, Bleuler-Martinez S, Plaza DF, Künzler M, Aebi M, Joachim A, Razzazi-Fazeli E, Jantsch V, Geyer R, Wilson IB, Paschinger K. Galactosylated fucose epitopes in nematodes: increased expression in a Caenorhabditis mutant associated with altered lectin sensitivity and occurrence in parasitic species. J Biol Chem 2012 287(34) 28276-90  [ PubMed ID = 22733825 ] [ RRC reference ] Paschinger K, Gutternigg M, Rendić D, Wilson IB. The N-glycosylation pattern of Caenorhabditis elegans. Carbohydr Res 2008 343(12) 2041-9  [ PubMed ID = 18226806 ] [ RRC reference ] Gutternigg M, Kretschmer-Lubich D, Paschinger K, Rendić D, Hader J, Geier P, Ranftl R, Jantsch V, Lochnit G, Wilson IB. Biosynthesis of truncated N-linked oligosaccharides results from non-orthologous hexosaminidase-mediated mechanisms in nematodes, plants, and insects. J Biol Chem 2007 282(38) 27825-40  [ PubMed ID = 17636254 ] [ RRC reference ]