分離済み変異体

tm2312

Allele Nametm2312
BalanceCompleted
OutCrossNot Accepted
Sequence NameY47G6A.10
Gene Namespg-7
Worm BaseAllele Name tm2312 (x1)
Gene Name spg-7
Sequence Y47G6A.10
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 38042/38043-38437/38438 (395 bp deletion)
ChromosomeI
Putative gene structurejoin(34540..34659, 34709..34871, 34914..34986, 36692..36890, 36948..37072, 37988..39133, 39850..39958, 43924..44043, 44497..44706, 45062..45355)
Map position-3.22
BalancerhT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersIntRev:GTGCATATCCGAGACCCTTT,ExtRev:TACCGATCAAGCAACTGATC,IntFwd:CAAACCTCATCAGCGTCGCA,ExtFwd:CGCGAAATCCCAAACCTCAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Chaudhari SN, Kipreos ET.
Increased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways.
Nat Commun 2017 8(1) 182 
[ PubMed ID = 28769038 ] [ RRC reference ]

Zubovych IO, Straud S, Roth MG.
Mitochondrial dysfunction confers resistance to multiple drugs in Caenorhabditis elegans.
Mol Biol Cell 2010 21(6) 956-69 
[ PubMed ID = 20089839 ] [ RRC reference ]