分離済み変異体

tm2290

Allele Nametm2290
BalanceNot Required
OutCrossNot Accepted
Sequence NameT05H4.1
Gene Nameacl-8
Worm BaseAllele Name tm2290
Gene Name acl-8
Sequence T05H4.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 40960/40961-GKGTAAGTTG-44791/44792 (3831 bp deletion + 10 bp insertion)
ChromosomeV
Putative gene structurejoin(40786..40950, 41016..41484, 41544..41638, 41756..41920, 41979..42119)
Map position-0.15
Balancer
Map position of balancer
Sequence of primersIntRev:AGGCACCTCATAGTGGTTGC,ExtRev:TAGTGCGGAAGAGAACTTGT,IntFwd:TCCTCACTTCTCGGAACTGT,ExtFwd:CGACTGTGCTTCTCGACTAA
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Imae R, Inoue T, Nakasaki Y, Uchida Y, Ohba Y, Kono N, Nakanishi H, Sasaki T, Mitani S, Arai H.
LYCAT, a homologue of C. elegans acl-8, acl-9, and acl-10, determines the fatty acid composition of phosphatidylinositol in mice.
J Lipid Res 2012 53(3) 335-347 
[ PubMed ID = 22172515 ] [ RRC reference ]

Imae R, Inoue T, Kimura M, Kanamori T, Tomioka NH, Kage-Nakadai E, Mitani S, Arai H.
Intracellular phospholipase A1 and acyltransferase, which are involved in Caenorhabditis elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol.
Mol Biol Cell 2010 21(18) 3114-24 
[ PubMed ID = 20668164 ] [ RRC reference ]