分離済み変異体

tm2258

Allele Name

tm2258

Allele Type

通常株

Sequence Name

F59F5.1

Gene Name

slcf-1

Worm Base

Allele Name

tm2258

Gene Name

slcf-1

Sequence

F59F5.1

Phenotype

homozygous viable

Mutation site

895/896-1560/1561 (665 bp deletion)

Chromosome

Putative gene structure

join(263..268, 314..419, 466..606, 657..808, 854..982, 1034..1149, 1198..1279, 1512..1635, 1682..2079)

Map position

2.23

Balancer

Map position of balancer

Sequence of primers

IntRev:GCAACTCGCACAGAAGGCAA,ExtRev:GATACGGTTGCTTGTGACGT,IntFwd:CCAAGCCGATACTGCGGTTT,ExtFwd:ACGGATTTGTCGAGCCTGTC

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Butler JA, Mishur RJ, Bhaskaran S, Rea SL.
A metabolic signature for long life in the Caenorhabditis elegans Mit mutants.
Aging Cell 2013 12(1) 130-8
[ PubMed ID = 23173729 ] [ RRC reference ]

Wong A, Li X, Molin L, Solari F, Elena-Herrmann B, Sakellariou D.
μHigh resolution-magic-angle spinning NMR spectroscopy for metabolic phenotyping of Caenorhabditis elegans.
Anal Chem 2014 86(12) 6064-70
[ PubMed ID = 24897622 ] [ RRC reference ]

Pontoizeau C, Mouchiroud L, Molin L, Mergoud-Dit-Lamarche A, Dallière N, Toulhoat P, Elena-Herrmann B, Solari F.
Metabolomics analysis uncovers that dietary restriction buffers metabolic changes associated with aging in Caenorhabditis elegans.
J Proteome Res 2014 13(6) 2910-9
[ PubMed ID = 24819046 ] [ RRC reference ]

Shafaq-Zadah M, Brocard L, Solari F, Michaux G.
AP-1 is required for the maintenance of apico-basal polarity in the C. elegans intestine.
Development 2012 139(11) 2061-70
[ PubMed ID = 22535414 ] [ RRC reference ]

Mouchiroud L, Molin L, Kasturi P, Triba MN, Dumas ME, Wilson MC, Halestrap AP, Roussel D, Masse I, Dallière N, Ségalat L, Billaud M, Solari F.
Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans.
Aging Cell 2011 10(1) 39-54
[ PubMed ID = 21040400 ] [ RRC reference ]