Home > 分離済み変異体 > tm2235

分離済み変異体

Allele Name		tm2235
Allele Type		通常株
Sequence Name		Y110A2AL.13
Gene Name		pinn-1
Worm Base	Allele Name	tm2235
	Gene Name	pinn-1
	Sequence	Y110A2AL.13
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. K.F. O'Connell: normal hatching, locomotion and body shape.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		52164/52165-52528/52529 (364 bp deletion)
Chromosome		II
Putative gene structure		complement(join(49933..50055, 50799..50905, 52115..52262, 52371..52444, 52492..52546))
Map position		-9.56
Balancer
Map position of balancer
Sequence of primers		ExtRev:ATACGGGCCAATTTTCCAGA,IntRev:GATGTCCGATAATTCGCTGC,IntFwd:CCCTCAATGTTCGACGCATC,ExtFwd:GGCGGTTACAGTACCCCAAG
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Salzberg Y, Pechuk V, Gat A, Setty H, Sela S, Oren-Suissa M. Synaptic Protein Degradation Controls Sexually Dimorphic Circuits through Regulation of DCC/UNC-40. Curr Biol 2020 30(21) 4128-4141.e5  [ PubMed ID = 32857970 ] [ RRC reference ] Chuang M, Hsiao TI, Tong A, Xu S, Chisholm AD. DAPK interacts with Patronin and the microtubule cytoskeleton in epidermal development and wound repair. Elife 2016 5   [ PubMed ID = 27661253 ] [ RRC reference ] Chen F, Chisholm AD, Jin Y. Tissue-specific regulation of alternative polyadenylation represses expression of a neuronal ankyrin isoform in C. elegans epidermal development. Development 2017 144(4) 698-707  [ PubMed ID = 28087624 ] [ RRC reference ] Del Rosario JS, Feldmann KG, Ahmed T, Amjad U, Ko B, An J, Mahmud T, Salama M, Mei S, Asemota D, Mano I. Death Associated Protein Kinase (DAPK) -mediated neurodegenerative mechanisms in nematode excitotoxicity. BMC Neurosci 2015 16 25  [ PubMed ID = 25899010 ] [ RRC reference ]