分離済み変異体

tm2144

Allele Name

tm2144

Balance

Not Required

OutCross

Not Accepted

Sequence Name

R13F6.10

Gene Name

cra-1

Worm Base

Allele Name

tm2144

Gene Name

cra-1

Sequence

R13F6.10

Phenotype

homozygous viable. Dr. M. Colaiacovo: Plos Genetics, 4, e1000088 (2008).

Mutation site

33513/33514-34266/34267 (753 bp deletion)

Chromosome

III

Putative gene structure

complement(join(30595..30702, 30776..30946, 30987..31216, 31261..31615, 31664..31773, 31832..31949, 31995..32090, 32146..32315, 32364..32474, 32523..32601, 32655..32777, 32829..32927, 32975..33215, 33266..33361, 33443..33741, 33793..33889, 33943..34049, 34097..34225, 34273..34358, 34412..34463))

Map position

-0.91

Balancer

Map position of balancer

Sequence of primers

IntFwd:GTACCGCGGCGATTTGTGCA,ExtRev:CGTTCGAACGTGGAAAGGCT,ExtFwd:TATTGGAGGCGGCCACGAAT,IntRev:CAGATGCGCTCCACCGCTAA

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Rog O, Köhler S, Dernburg AF.
The synaptonemal complex has liquid crystalline properties and spatially regulates meiotic recombination factors.
Elife 2017 6
[ PubMed ID = 28045371 ] [ RRC reference ]

Gao J, Kim HM, Elia AE, Elledge SJ, Colaiácovo MP.
NatB domain-containing CRA-1 antagonizes hydrolase ACER-1 linking acetyl-CoA metabolism to the initiation of recombination during C. elegans meiosis.
PLoS Genet 2015 11(3) e1005029
[ PubMed ID = 25768301 ] [ RRC reference ]

Baudrimont A, Penkner A, Woglar A, Machacek T, Wegrostek C, Gloggnitzer J, Fridkin A, Klein F, Gruenbaum Y, Pasierbek P, Jantsch V.
Leptotene/zygotene chromosome movement via the SUN/KASH protein bridge in Caenorhabditis elegans.
PLoS Genet 2010 6(11) e1001219
[ PubMed ID = 21124819 ] [ RRC reference ]

Smolikov S, Schild-Prüfert K, Colaiácovo MP.
CRA-1 uncovers a double-strand break-dependent pathway promoting the assembly of central region proteins on chromosome axes during C. elegans meiosis.
PLoS Genet 2008 4(6) e1000088
[ PubMed ID = 18535664 ] [ RRC reference ]