分離済み変異体

tm1974

Allele Nametm1974
Allele Type通常株
Sequence NameY24F12A.2
Gene Nameragc-1
Worm BaseAllele Name tm1974
Gene Name ragc-1
Sequence Y24F12A.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 627/638-1036/1037 (409 bp deletion)
ChromosomeIV
Putative gene structurejoin(complement(993..1099), complement(849..943), complement(325..770), complement(137..279), complement(Z73426.1:15881..16106))
Map position5.04
Balancer
Map position of balancer
Sequence of primersIntFwd:AACGAGGGCAAGATGCTTGT,ExtFwd:CCTATCGGAATTGCCTGGTT,IntRev:AGCCTTCTTGCGAGAGCTCA,ExtRev:TCTCCCGGGTGGAACATAAA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Murphy JT, Liu H, Ma X, Shaver A, Egan BM, Oh C, Boyko A, Mazer T, Ang S, Khopkar R, Javaheri A, Kumar S, Jiang X, Ory D, Mani K, Matkovich SJ, Kornfeld K, Diwan A.
Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival.
PLoS Biol 2019 17(5) e3000245 
[ PubMed ID = 31086360 ] [ RRC reference ]

Fukuyama M, Sakuma K, Park R, Kasuga H, Nagaya R, Atsumi Y, Shimomura Y, Takahashi S, Kajiho H, Rougvie A, Kontani K, Katada T.
C. elegans AMPKs promote survival and arrest germline development during nutrient stress.
Biol Open 2012 1(10) 929-36 
[ PubMed ID = 23213370 ] [ RRC reference ]

Fukuyama M, Kontani K, Katada T, Rougvie AE.
The C. elegans Hypodermis Couples Progenitor Cell Quiescence to the Dietary State.
Curr Biol 2015 25(9) 1241-8 
[ PubMed ID = 25891400 ] [ RRC reference ]