分離済み変異体

tm1931

Allele Nametm1931
Allele Type通常株
Sequence NameB0213.4
Gene Namenlp-29
Worm BaseAllele Name tm1931
Gene Name nlp-29
Sequence B0213.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. C. Kenyon: grossly normal morphology and fertility, does not form dauer at 25C.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 32394/32395-AAAA-32888/32889 (494 bp deletion + 4 bp insertion)
ChromosomeV
Putative gene structurejoin(32374..32464, 32534..32664)
Map position-7.34
Balancer
Map position of balancer
Sequence of primersExtRev:GGCTGCTGACTCCTGACAGT,IntRev:GACCAACGTCCTTCACGGGA,ExtFwd:ATGCTGCATGTGAAATCGCA,IntFwd:GGTCAGAAATGTTGCCCATA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
E L, Zhou T, Koh S, Chuang M, Sharma R, Pujol N, Chisholm AD, Eroglu C, Matsunami H, Yan D.
An Antimicrobial Peptide and Its Neuronal Receptor Regulate Dendrite Degeneration in Aging and Infection.
Neuron 2018 97(1) 125-138.e5 
[ PubMed ID = 29301098 ] [ RRC reference ]

Pujol N, Zugasti O, Wong D, Couillault C, Kurz CL, Schulenburg H, Ewbank JJ.
Anti-fungal innate immunity in C. elegans is enhanced by evolutionary diversification of antimicrobial peptides.
PLoS Pathog 2008 4(7) e1000105 
[ PubMed ID = 18636113 ] [ RRC reference ]