分離済み変異体

tm1821

Allele Name

tm1821

Balance

Completed

OutCross

Not Accepted

Sequence Name

T26A5.7

Gene Name

set-1

Worm Base

Allele Name

tm1821 (x1)

Gene Name

set-1

Sequence

T26A5.7

Phenotype

lethal or sterile. Dr. R.H. Horvitz: recessive sterile, not synMuv with class A or B mutations and not a synMuv suppressor.

Mutation site

3813/3814-4744/4745 (931 bp deletion)

Chromosome

III

Putative gene structure

complement(join(3510..3647, 3736..3923, 3978..4216, 4350..4529, 4634..4755))

Map position

-1.26

Balancer

hT2

Map position of balancer

Sequence of primers

ExtFwd:CGCACCTCATGTACACCACA,IntFwd:GTAATGAGAGGATTGGGCAC,ExtRev:GCACTTCCCGCCAAAACCAT,IntRev:ATTTAGTCGCGTGTGCACGA

Distributed lab

Depositor

Dr. S. Mitani

References

Please submit your publication

Kramer M, Kranz AL, Su A, Winterkorn LH, Albritton SE, Ercan S.
Developmental Dynamics of X-Chromosome Dosage Compensation by the DCC and H4K20me1 in C. elegans.
PLoS Genet 2015 11(12) e1005698
[ PubMed ID = 26641248 ] [ RRC reference ]

Lau AC, Nabeshima K, Csankovszki G.
The C. elegans dosage compensation complex mediates interphase X chromosome compaction.
Epigenetics Chromatin 2014 7(1) 31
[ PubMed ID = 25400696 ] [ RRC reference ]

Vielle A, Lang J, Dong Y, Ercan S, Kotwaliwale C, Rechtsteiner A, Appert A, Chen QB, Dose A, Egelhofer T, Kimura H, Stempor P, Dernburg A, Lieb JD, Strome S, Ahringer J.
H4K20me1 contributes to downregulation of X-linked genes for C. elegans dosage compensation.
PLoS Genet 2012 8(9) e1002933
[ PubMed ID = 23028348 ] [ RRC reference ]

Wells MB, Snyder MJ, Custer LM, Csankovszki G.
Caenorhabditis elegans dosage compensation regulates histone H4 chromatin state on X chromosomes.
Mol Cell Biol 2012 32(9) 1710-9
[ PubMed ID = 22393255 ] [ RRC reference ]