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3. Genome analysis in Triticum and Aegilops

Guided by the principles of genome homology, he and his colleagues developed the methodology for phylogenic classification of plant species, called as genome analysis. The genome analysis is mainly based on the degree of meiotic chromosome pairing in interspecific hybrids, in addition to karyotyping and comparative analysis of morphological characters between the concerned species. Kihara's studies were very systematic ones; he included always positive and negative controls when he conducted the experiments, that is, he used three diploid species as the analyzers whose genome had been known to be different each other to determine the genome constitution of the given material.

After systematic observations of chromosome pairing in interspecific hybrids, he concluded that a common wheat consists of three different kinds of genome, namely A, B, and D, and that emmer wheat had two common genomes, A and B, with common wheat. The genome formula of einkorn, T. monococcum and its wild species T. boeoticum were commonly designated as A. D was designated for Ae. squarrosa and the third genome of common wheat.

The genome analysis was conducted in the related species of wheat covering all Triticum and Aegilops species by him and his colleagues, revealing that these genera consisted of eight basic genomes and their modifiers; A, B, C, Cu(U), D, M, Mt, and S. Polyploid species were proved to be constructed from the combinations of these genomes. This study had been initiated in early 1930's and concluded in 1972. His conclusions and the designated genome formulas in Triticum and Aegilops were essentially accepted by further detail analyses with cytological, cytoplasmic and molecular examinations by recent investigators (see "Nuclear and organelar genomes of wheat species" edited by Sasakuma 1992 for the details).

These discoveries led one of the important concepts of plant evolution; some plant species contain multiple differentiated genomes in their nucleus, that is, allo-polyploidy. This indicated that these species had generated through interspecific hybridization and successive amphiploidization in plant evolution.


4. Disconvery of ancestral progenitors of common wheat

It was in 1945 just after the world war II, that Dr. Kihara become a world-wide famous geneticist as a discoverer of wheat ancestral progenitors, when American military mission visited his laboratory to search for scientific development during the war. He explained experimental and theoretical results that Ae. squarrosa should be a progenitor to D genome of hexaploid common wheat by means of genome analysis, as well as morphological analysis. He was noticed that the same conclusion had been independently achieved by Dr. Earnest R. Sears in University of Mioussouri, Colombia, USA at almost the same time (McFadden and Sears 1944). This coincidence is symbolic for the two big scientists in the wheat research.

Not only these analytical examinations, he employed two further methodologies to reach the conclusion. He made several hybridization experiment between emmer wheat and squarrosa accessions to produce ABD amphiploids called as synthetic wheats. These synthetic wheats were then crossed with conventional common wheats, and F1 and F2 progenies were cytologically and genetically examined. Since these synthetic wheats exhibited genomically identical to common wheat, it was sure that squarrosa is the D-genome progenitor to hexaploid common wheat. The thrid and final method was the ecological one. In 1954, he organized a plant expedition team (Kyoto University Scientific Expedition to Karakram Hindukush) to examine ecological distribution and habitat of squarrosa in Middle East. They found that squarrosa grew in the cultivated field of emmer wheat as a field weed, suggesting a possibility of natural hybridization to generate hexaploid wheat in nature. (See the picture in this page which shows the moment that Kihara found natural habitat of squarrosa in the suburbs of Gorgan, Iran in 1954.)

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