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Most interspecific hybrids from crosses between species with well-differentiated genomes are highly sterile due to interactions between the specific genes of the parental speceis, which complement sterility due to meiotic irregularities. Only natural or induced amphidiploids and some of the progenies from backcrosses with parental species or from out-crosses with other related species are fertile, and these progenies can be used for the analysis of the hybrid sterility components. Sterility may be due to hemizygosity of the species-specific genes in the F1, and fertility is restored when these genes become homozygous in the amphidiploid, or sterility genes from one of the parents may be eliminated in certain fertile backcross progenies. If parental species differ cytoplasmically, then cytoplasm-specific nuclear genes from the genome of the cytoplasm donor species may be transferred to the chromosomal complement of the recurrent male parent which usually is T. aestivum or T. durum. The use of polyploid T. aestivum facilitates the transfer of the alien genes to wheat chromosomes because a greater variety of the aneuploid gametes and zygotes produced are viable and functional, and the effects of aneuploidy and sterility due to meiotic irregularities are minimized. Of course, only those alien genes which are expressed in the genetic background of T. aestivum would be identified and examined. Others, which are not transferred to wheat, or remain unexpressed, or those having minor effects will remain unidentified. Genes controlling most easily noticeable cytoplasmic effects like restoration of male fertility and vigor of hybrid plants are examined most often. In most species, the genes controlling restoration of male fertility and plant vigor appear to be closely linked or are located on the same arm of a critical chromosome of the cytoplasm donor species (MAAN, 1977b). The presence of the alicn chromosome in wheat plants can be readily detected when derived hybrid progenies are crossed with alloplasmic wheat lines having cytoplasm of the same donor species from which the critical nuclear genes were extracted, and F1's are cytologically examined for lack of pairing between wheat and alien chromosome(s) and from other phenotypic effects.


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