Strain Name: giraffe (gir) / Allele: rw716

Allele rw716
Strain Name giraffe (gir)
Type Mutant
Genotype cyp26a1rw716/rw716
Affected Gene cyp26A
Origin and Depositor Tokyo Institute of Technology (Yoshiyuki Imai)
Link to ZFIN ZDB-GENO-050324-1    
Information
"A mutant of the zebrafish named giraffe (gir) in which the gene for the RA-degrading enzyme Cyp26a1 is mutated. The gir mutant displayed patterning defects in multiple organs including the common cardinal vein, pectoral fin, tail, hindbrain, and spinal cord."  
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Reference

Emoto Y, Wada H, Okamoto H, Kudo A, Imai Y. Retinoic acid-metabolizing enzyme Cyp26a1 is essential for determining territories of hindbrain and spinal cord in zebrafish. Dev. Biol. 2005 ; 278(2) : 415-427 .

 
Facility RIKEN Center for Brain Science