Strain Name: landlocked / Allele: rw16
|Origin and Depositor||RIKEN CBS (Hitoshi Okamoto)|
|Link to ZFIN||ZDB-GENO-050711-2|
|Mutant shows highly specific defects in the caudal migration of the nVII motor neurons. The maternal and zygotic mutant shows defects in convergent extension (CE) movements during gastrulation. rw16 allele has a point mutation (amino acid substitution) in the first PDZ domain of Scrb1.|
|The Conditions to Distribute Strains|
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Wada, H., Iwasaki, M., Sato, T., Masai, I., Nishiwaki, Y., Tanaka, H., Sato, A., Nojima, Y., and Okamoto, H. (2005) Dual roles of zygotic and maternal Scribble1 in neural migration and convergent extension movements in zebrafish embryos. Development 132(10):2273-2285
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
|Facility||RIKEN (Wako) CBS, Lab for Neural Circuit Dynamics of Decision Making|