Strain Name: landlocked / Allele: rw468

Allele rw468
Strain Name landlocked
Type Mutant
Genotype scribrw468/rw468
Affected Gene scribble1
Origin and Depositor RIKEN CBS (Hitoshi Okamoto)
Link to ZFIN ZDB-GENO-050711-3    
Information
Mutant shows highly specific defects in the caudal migration of the nVII motor neurons.The maternal and zygotic mutant shows defects in convergent extension (CE) movements during gastrulation.rw468 allele has a point mutation (stop codon) in the LRR domain of Scrb1.  
The Conditions to Distribute Strains
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Wada, H., Iwasaki, M., Sato, T., Masai, I., Nishiwaki, Y., Tanaka, H., Sato, A., Nojima, Y., and Okamoto, H. (2005) Dual roles of zygotic and maternal Scribble1 in neural migration and convergent extension movements in zebrafish embryos. Development 132(10):2273-2285
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.  
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Reference

Wada H, Iwasaki M, Sato T, Masai I, Nishiwaki Y, Tanaka H, Sato A, Nojima Y, Okamoto H. Dual roles of zygotic and maternal Scribble1 in neural migration and convergent extension movements in zebrafish embryos. Development. 2005 ; 132(10) : 2273-2285 .

 
Facility RIKEN Center for Brain Science