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Reference Detail
| Reference | ||
|---|---|---|
| Author | Fan Y., Ma L., Pan X., Tian P., Wang W., Liu K., Xiong Z., Li C., Wang Z., Wang J., Zhang H., Bao Y. | |
| Title | Genome-Wide Association Study Identifies Rice Panicle Blast-Resistant Gene <i>Pb4</i> Encoding a Wall-Associated Kinase. | |
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Abstract: Rice blast is one of the most devastating diseases, causing a significant reduction in global rice production. Developing and utilizing resistant varieties has proven to be the most efficient and cost-effective approach to control blasts. However, due to environmental pressure and intense pathogenic selection, resistance has rapidly broken down, and more durable resistance genes are being discovered. In this paper, a novel Wall-Associated Kinase (WAK) gene, <i>Pb4</i>, which confers resistance to rice blast, was identified through a genome-wide association study (GWAS) utilizing 249 rice accessions. Pb4 comprises an N-terminal signal peptide, extracellular GUB domain, EGF domain, EGF-Ca2+ domain, and intracellular Ser/Thr protein kinase domain. The extracellular domain (GUB domain, EGF domain, and EGF-Ca2+ domain) of Pb4 can interact with the extracellular domain of CEBiP. Additionally, its expression is induced by chitin and polygalacturonic acid. Furthermore, transgenic plants overexpressing <i>Pb4</i> enhance resistance to rice blast. In summary, this study identified a novel rice blast-resistant gene, <i>Pb4</i>, and provides a theoretical basis for understanding the role of WAKs in mediating rice resistance against rice blast disease. |
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| Journal | Int J Mol Sci | |
| Country | China | |
| Volume | 25(2) | |
| Pages | ||
| Year | 2024 | |
| PubMed ID | 38255904 | |
| PubMed Central ID | 10815793 | |
| DOI | 10.3390/ijms25020830 | |
| URL | - | |
| Relation | ||
| Gene | CEBIP PB4 | |
| INSD | - | |
| Strain | Wild Core Collection | - |
| Induced Mutation Lines(NIG Collection) | - | |
| Sterile Seed Strain | - | |
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Lethal Embryo Mutantion Strain |
- | |
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Stages in Each Organ - Muant Lines (Gene) |
- | |
| Cultivated Varieties(NIG Collection) | - | |
| Stages in Each Organ | - | |
