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Reference Detail
| Reference | ||
|---|---|---|
| Author | Sun Y., Xie Z., Jin L., Qin T., Zhan C., Huang J. | |
| Title | Histone deacetylase OsHDA716 represses rice chilling tolerance by deacetylating OsbZIP46 to reduce its transactivation function and protein stability. | |
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Abstract: Low temperature is a major environmental factor limiting plant growth and crop production. Epigenetic regulation of gene expression is important for plant adaptation to environmental changes, whereas the epigenetic mechanism of cold signaling in rice (Oryza sativa) remains largely elusive. Here, we report that the histone deacetylase OsHDA716 represses rice cold tolerance by interacting with and deacetylating the transcription factor OsbZIP46. The loss-of-function mutants of OsHDA716 exhibit enhanced chilling tolerance, compared to the wild-type plants, while OsHDA716-overexpression plants show chilling hypersensitivity. On the contrary, OsbZIP46 confers chilling tolerance in rice through transcriptionally activating OsDREB1A and COLD1 to regulate cold-induced calcium influx and cytoplasmic calcium elevation. Mechanistic investigation showed that OsHDA716-mediated OsbZIP46 deacetylation in the DNA-binding domain reduces the DNA-binding ability and transcriptional activity as well as decreasing OsbZIP46 protein stability. Genetic evidence indicated that OsbZIP46 deacetylation mediated by OsHDA716 reduces rice chilling tolerance. Collectively, these findings reveal that the functional interplay between the chromatin regulator and transcription factor fine-tunes the cold response in plant, and uncover a mechanism by which histone deacetylases repress gene transcription through deacetylating non-histone proteins and regulating their biochemical functions. |
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| Journal | Plant Cell | |
| Country | China | |
| Volume | ||
| Pages | ||
| Year | 2024 | |
| PubMed ID | 38242836 | |
| PubMed Central ID | - | |
| DOI | 10.1093/plcell/koae010 | |
| URL | - | |
| Relation | ||
| Gene | BZIP46 COLD1 DREB1A HDA716 | |
| INSD | - | |
| Strain | Wild Core Collection | - |
| Induced Mutation Lines(NIG Collection) | - | |
| Sterile Seed Strain | - | |
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Lethal Embryo Mutantion Strain |
- | |
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Stages in Each Organ - Muant Lines (Gene) |
- | |
| Cultivated Varieties(NIG Collection) | - | |
| Stages in Each Organ | - | |
