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Reference Detail
| Reference | ||
|---|---|---|
| Author | Jang M.J., Hong W.J., Park Y.S., Jung K.H., Kim S. | |
| Title | Genomic basis of multiphase evolution driving divergent selection of zinc-finger homeodomain genes. | |
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Abstract: Gene families divergently evolve and become adapted as different genes with specific structures and functions in living organisms. We performed comprehensive structural and functional analyses of Zinc-finger homeodomain genes (ZF-HDs), including Mini zinc-finger genes (MIFs) and Zinc-finger with homeodomain genes (ZHDs), displaying competitive functions each other. Intensive annotation updates for 90 plant genomes verified that most MIFs (MIF-Is) exhibited distinct motif compositions from ZHDs, although some MIFs (MIF-Zs) contained ZHD-specific motifs. Phylogenetic analyses suggested that MIF-Zs and ZHDs originated from the same ancestral gene, whereas MIF-Is emerged from a distinct progenitor. We used a gene-editing system to identify a novel function of MIF-Is in rice: regulating the surface material patterns in anthers and pollen through transcriptional regulation by interacting ZHDs. Kingdom-wide investigations determined that (i) ancestral MIFs diverged into MIF-Is and MIF-Zs in the last universal common ancestor, (ii) integration of HD into the C-terminal of MIF-Zs created ZHDs after emergence of green plants and (iii) MIF-Is and ZHDs subsequently expanded independently into specific plant lineages, with additional formation of MIF-Zs from ZHDs. Our comprehensive analysis provides genomic evidence for multiphase evolution driving divergent selection of ZF-HDs. |
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| Journal | Nucleic Acids Res. | |
| Country | South Korea | |
| Volume | 51(14) | |
| Pages | 7424-7437 | |
| Year | 2023 | |
| PubMed ID | 37394281 | |
| PubMed Central ID | 10415114 | |
| DOI | 10.1093/nar/gkad489 | |
| URL | - | |
| Relation | ||
| Gene | ACL-D DREB1A DREB1B PASPRO1 PASPRO2 ZHD9 | |
| INSD | - | |
| Strain | Wild Core Collection | - |
| Induced Mutation Lines(NIG Collection) | - | |
| Sterile Seed Strain | - | |
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Lethal Embryo Mutantion Strain |
- | |
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Stages in Each Organ - Muant Lines (Gene) |
- | |
| Cultivated Varieties(NIG Collection) | - | |
| Stages in Each Organ | - | |
