Update info.Tools - Reference - Detail
Reference Detail
| Reference | ||
|---|---|---|
| Author | Hao Z., Tian J., Fang H., Fang L., Xu X., He F., Li S., Xie W., Du Q., You X., Wang D., Chen Q., Wang R., Zuo S., Yuan M., Wang G.L., Xia L., Ning Y. | |
| Title | A VQ-motif-containing protein fine-tunes rice immunity and growth by a hierarchical regulatory mechanism. | |
|
Abstract: Rice blast and bacterial blight, caused by the fungus Magnaporthe oryzae and the bacterium Xanthomonas oryzae pv. oryzae (Xoo), respectively, are devastating diseases affecting rice. Here, we report that a rice valine-glutamine (VQ) motif-containing protein, OsVQ25, balances broad-spectrum disease resistance and plant growth by interacting with a U-Box E3 ligase, OsPUB73, and a transcription factor, OsWRKY53. We show that OsPUB73 positively regulates rice resistance against M. oryzae and Xoo by interacting with and promoting OsVQ25 degradation via the 26S proteasome pathway. Knockout mutants of OsVQ25 exhibit enhanced resistance to both pathogens without a growth penalty. Furthermore, OsVQ25 interacts with and suppresses the transcriptional activity of OsWRKY53, a positive regulator of plant immunity. OsWRKY53 downstream defense-related genes and brassinosteroid signaling genes are upregulated in OsVQ25 mutants. Our findings reveal a ubiquitin E3 ligase-VQ protein-transcription factor module that fine-tunes plant immunity and growth at the transcriptional and posttranslational levels. |
||
| Journal | Cell Rep | |
| Country | China | |
| Volume | 40(7) | |
| Pages | 111235 | |
| Year | 2022 | |
| PubMed ID | 35977497 | |
| PubMed Central ID | - | |
| DOI | 10.1016/j.celrep.2022.111235 | |
| URL | - | |
| Relation | ||
| Gene | BU1 PR10A PUB73 VQ25 WRKY45 WRKY53 XTH2 _ _ | |
| INSD | - | |
| Strain | Wild Core Collection | - |
| Induced Mutation Lines(NIG Collection) | - | |
| Sterile Seed Strain | - | |
|
Lethal Embryo Mutantion Strain |
- | |
|
Stages in Each Organ - Muant Lines (Gene) |
- | |
| Cultivated Varieties(NIG Collection) | - | |
| Stages in Each Organ | - | |
