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Reference Detail
| Reference | ||
|---|---|---|
| Author | Zhang Z., Li Z., Wang W., Jiang Z., Guo L., Wang X., Qian Y., Huang X., Liu Y., Liu X., Qiu Y., Li A., Yan Y., Xie J., Cao S., Kopriva S., Li L., Kong F., Liu B., Wang Y., Hu B., Chu C. | |
| Title | Modulation of nitrate-induced phosphate response by the MYB transcription factor RLI1/HINGE1 in the nucleus. | |
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Abstract: The coordinated utilization of nitrogen (N) and phosphorus (P) is vital for plants to maintain nutrient balance and achieve optimal growth. Previously, we revealed a mechanism by which nitrate induces genes for phosphate utilization; this mechanism depends on NRT1.1B-facilitated degradation of cytoplasmic SPX4, which in turn promotes cytoplasmic-nuclear shuttling of PHR2, the central transcription factor of phosphate signaling, and triggers the nitrate-induced phosphate response (NIPR) and N-P coordinated utilization in rice. In this study, we unveiled a fine-tuning mechanism of NIPR in the nucleus regulated by Highly Induced by Nitrate Gene 1 (HINGE1, also known as RLI1), a MYB-transcription factor closely related to PHR2. RLI1/HINGE1, which is transcriptionally activated by PHR2 under nitrate induction, can directly activate the expression of phosphate starvation-induced genes. More importantly, RLI1/HINGE1 competes with PHR2 for binding to its repressor proteins in the nucleus (SPX proteins), and consequently releases PHR2 to further enhance phosphate response. Therefore, RLI1/HINGE1 amplifies the phosphate response in the nucleus downstream of the cytoplasmic SPX4-PHR2 cascade, thereby enabling fine-tuning of N-P balance when nitrate supply is sufficient. |
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| Journal | Mol Plant | |
| Country | China | |
| Volume | 14(3) | |
| Pages | 517-529 | |
| Year | 2021 | |
| PubMed ID | 33316467 | |
| PubMed Central ID | - | |
| DOI | 10.1016/j.molp.2020.12.005 | |
| URL | - | |
| Relation | ||
| Gene | ERF69 GRAS47 HINGE3 LBD22 NIGT1 NPF6.5 PHR2 PT6 RLI1 SPX1 SPX2 SPX4 | |
| INSD | - | |
| Strain | Wild Core Collection | - |
| Induced Mutation Lines(NIG Collection) | - | |
| Sterile Seed Strain | - | |
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Lethal Embryo Mutantion Strain |
- | |
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Stages in Each Organ - Muant Lines (Gene) |
- | |
| Cultivated Varieties(NIG Collection) | - | |
| Stages in Each Organ | - | |
