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| Reference | ||
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| Author | Zhao H., Ma B., Kai-Xuan Duan, Xin-Kai Li, Lu X., Cui-Cui Yin, Jian-Jun Tao, Wei W., Wan-Ke Zhang, Pei-Yong Xin, Sin Man Lam, Jin-Fang Chu, Guang-Hou Shui, Shou-Yi Chen, Jin-Song Zhang | |
| Title | The GDSL Lipase MHZ11 Modulates Ethylene Signaling in Rice Roots. | |
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Abstract: Ethylene plays important roles in plant growth and development, but the regulation of ethylene signaling is largely unclear, especially in crops such as rice (<i>Oryza sativa</i>). Here, by analysis of the ethylene-insensitive mutant <i>mao huzi 11</i> (<i>MHZ11</i>), we identified the GDSL lipase MHZ11, which modulates ethylene signaling in rice roots. MHZ11 localized to the endoplasmic reticulum membrane and has acyl-hydrolyzing activity. This activity affects the homeostasis of sterols in rice roots and is required for root ethylene response. <i>MHZ11</i> overexpression caused constitutive ethylene response in roots. Genetically, <i>MHZ11</i> acts with the ethylene receptor <i>ETHYLENE RESPONSE SENSOR2</i> (<i>OsERS2</i>) upstream of <i>CONSTITUTIVE TRIPLE RESPONSE2</i> (<i>OsCTR2</i>) and <i>ETHYLENE INSENSITIVE2</i> (<i>OsEIN2</i>). The <i>MHZ11</i> mutant maintains more OsCTR2 in the phosphorylated form whereas <i>MHZ11</i> overexpression promotes ethylene-mediated inhibition of OsCTR2 phosphorylation. MHZ11 colocalized with the ethylene receptor OsERS2, and its effect on OsCTR2 phosphorylation requires ethylene perception and initiation of ethylene signaling. The <i>MHZ11</i> mutant overaccumulated sterols and blocking sterol biosynthesis partially rescued the <i>MHZ11</i> ethylene response, likely by reducing receptor-OsCTR2 interaction and OsCTR2 phosphorylation. We propose that MHZ11 reduces sterol levels to impair receptor-OsCTR2 interactions and OsCTR2 phosphorylation for triggering ethylene signaling. Our study reveals a mechanism by which MHZ11 participates in ethylene signaling for regulation of root growth in rice. |
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| Journal | Plant Cell | |
| Country | China | |
| Volume | 32(5) | |
| Pages | 1626-1643 | |
| Year | 2020 | |
| PubMed ID | 32184349 | |
| PubMed Central ID | 7203933 | |
| DOI | 10.1105/tpc.19.00840 | |
| URL | - | |
| Relation | ||
| Gene | CTR2 EIL1A EIN2 ERF2 ERS2 GELP64 RAP2.8 RR7 | |
| INSD | - | |
| Strain | Wild Core Collection | - |
| Induced Mutation Lines(NIG Collection) | - | |
| Sterile Seed Strain | - | |
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Lethal Embryo Mutantion Strain |
- | |
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Stages in Each Organ - Muant Lines (Gene) |
- | |
| Cultivated Varieties(NIG Collection) | - | |
| Stages in Each Organ | - | |
