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Reference Detail
| Reference | ||
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| Author | Zhao T., Ren L., Chen X., Yu H., Liu C., Shen Y., Shi W., Tang D., Du G., Li Y., Ma B., Cheng Z. | |
| Title | The OsRR24/LEPTO1 Type-B Response Regulator is Essential for the Organization of Leptotene Chromosomes in Rice Meiosis. | |
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Abstract: Response regulators play significant roles in controlling various biological processes; however, their roles in plant meiosis remain unclear. Here, we report the identification of OsRR24/LEPTOTENE1 (LEPTO1), a rice (<i>Oryza sativa</i>) type-B response regulator that participates in the establishment of key molecular and morphological features of chromosomes in leptotene, an early stage of prophase I in meiosis. Although meiosis initiates normally, as indicated by staining of the centromere-specific histone CENH3, the meiotic chromosomes in <i>LEPTO1</i> mutant pollen mother cells fail to form the thin thread-like structures that are typical of leptotene chromosomes in wild-type pollen mother cells. Furthermore, <i>LEPTO1</i> mutants fail to form chromosomal double-strand breaks, do not recruit meiosis-specific proteins to the meiotic chromosomes, and show disrupted callose deposition. LEPTO1 also is essential for programmed cell death in tapetal cells. LEPTO1 contains a conserved signal receiver domain (DDK) and a myb-like DNA binding domain at the N terminus. LEPTO1 interacts with two authentic histidine phosphotransfer (AHP) proteins, OsAHP1 and OsAHP2, via the DDK domain, and a phosphomimetic mutation of the DDK domain relieves its repression of LEPTO1 transactivation activity. Collectively, our results show that OsRR24/LEPTO1 plays a significant role in the leptotene phase of meiotic prophase I. |
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| Journal | Plant Cell | |
| Country | China | |
| Volume | 30(12) | |
| Pages | 3024-3037 | |
| Year | 2018 | |
| PubMed ID | 30538156 | |
| PubMed Central ID | 6354269 | |
| DOI | 10.1105/tpc.18.00479 | |
| URL | - | |
| Relation | ||
| Gene | AHP1 AHP2 AP37 CP1 CYCA1;1 CYCB1;4 DLC1 EAT1 RADC1 SDS TDR | |
| INSD | - | |
| Strain | Wild Core Collection | - |
| Induced Mutation Lines(NIG Collection) | - | |
| Sterile Seed Strain | - | |
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Lethal Embryo Mutantion Strain |
- | |
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Stages in Each Organ - Muant Lines (Gene) |
- | |
| Cultivated Varieties(NIG Collection) | - | |
| Stages in Each Organ | - | |
