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Author Fan J., Bai P., Ning Y., Wang J., Shi X., Xiong Y., Zhang K., He F., Zhang C., Wang R., Meng X., Zhou J., Wang M., Shirsekar G., Park C.H., Bellizzi M., Liu W., Jeon J.S., Xia Y., Shan L., Wang G.L.
Title The Monocot-Specific Receptor-like Kinase SDS2 Controls Cell Death and Immunity in Rice.
Abstract:
Programmed cell death (PCD) plays critical roles in plant immunity but must be regulated to prevent excessive damage. The E3 ubiquitin ligase SPL11 negatively regulates PCD and immunity in plants. We show that SPL11 cell-death suppressor 2 (SDS2), an S-domain receptor-like kinase, positively regulates PCD and immunity in rice by engaging and regulating SPL11 and related kinases controlling defense responses. An SDS2 mutant shows reduced immune responses and enhanced susceptibility to the blast fungus Magnaporthe oryzae. Conversely, SDS2 over-expression induces constitutive PCD accompanied by elevated immune responses and enhanced resistance to M. oryzae. SDS2 interacts with and phosphorylates SPL11, which in turn ubiquitinates SDS2, leading to its degradation. In addition, SDS2 interacts with related receptor-like cytoplasmic kinases, OsRLCK118/176, that positively regulate immunity by phosphorylating the NADPH oxidase OsRbohB to stimulate ROS production. Thus, a plasma membrane-resident protein complex consisting of SDS2, SPL11, and OsRLCK118/176 controls PCD and immunity in rice.
Journal Cell Host Microbe
Country USA
Volume 23(4)
Pages 498-510.e5
Year 2018
PubMed ID 29576481
PubMed Central ID -
DOI 10.1016/j.chom.2018.03.003
URL -
Relation
Gene PAL1 PR5 RBOHB RLCK118 RLCK176 SDS2 SPL11
INSD -
Strain Wild Core Collection -
Induced Mutation Lines(NIG Collection) -
Sterile Seed Strain -
Lethal Embryo
Mutantion Strain
-
Stages in Each Organ
- Muant Lines (Gene)
-
Cultivated Varieties(NIG Collection) -
Stages in Each Organ -
/rice/oryzabase