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著者 | Zhou H., Wang L., Liu G., Meng X., Jing Y., Shu X., Kong X., Sun J., Yu H., Smith S.M., Wu D., Li J. | |
タイトル | Critical roles of soluble starch synthase SSIIIa and granule-bound starch synthase Waxy in synthesizing resistant starch in rice. | |
Abstract: Changes in human lifestyle and food consumption have resulted in a large increase in the incidence of type-2 diabetes, obesity, and colon disease, especially in Asia. These conditions are a growing threat to human health, but consumption of foods high in resistant starch (RS) can potentially reduce their incidence. Strategies to increase RS in rice are limited by a lack of knowledge of its molecular basis. Through map-based cloning of a RS locus in indica rice, we have identified a defective soluble starch synthase gene (SSIIIa) responsible for RS production and further showed that RS production is dependent on the high expression of the Waxy(a) (Wx(a)) allele, which is prevalent in indica varieties. The resulting RS has modified granule structure; high amylose, lipid, and amylose-lipid complex; and altered physicochemical properties. This discovery provides an opportunity to increase RS content of cooked rice, especially in the indica varieties, which predominates in southern Asia. |
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掲載誌 | Proc. Natl. Acad. Sci. U.S.A. | |
Country | China | |
刊数 | ||
ページ | ||
発刊年 | 2016 | |
PubMed ID | 27791174 | |
PubMed Central ID | 5111662 | |
DOI | 10.1073/pnas.1615104113 | |
URL | - | |
関連情報 | ||
遺伝子 | FLO5 WX1 | |
INSD | - | |
系統 |
野生イネ コアコレクション |
- |
突然変異系統(遺伝研 Collection) | - | |
種子不稔系統 | - | |
致死変異体系統 | - | |
組織別発生段階 - 突然変異系統(遺伝子) |
- | |
栽培イネ品種(遺伝研 Collection) | - | |
組織別発生段階 | - |