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Author Yano K., Yamamoto E., Aya K., Takeuchi H., Lo P.C., Hu L., Yamasaki M., Yoshida S., Kitano H., Hirano K., Matsuoka M.
Title Genome-wide association study using whole-genome sequencing rapidly identifies new genes influencing agronomic traits in rice.
Abstract:
A genome-wide association study (GWAS) can be a powerful tool for the identification of genes associated with agronomic traits in crop species, but it is often hindered by population structure and the large extent of linkage disequilibrium. In this study, we identified agronomically important genes in rice using GWAS based on whole-genome sequencing, followed by the screening of candidate genes based on the estimated effect of nucleotide polymorphisms. Using this approach, we identified four new genes associated with agronomic traits. Some genes were undetectable by standard SNP analysis, but we detected them using gene-based association analysis. This study provides fundamental insights relevant to the rapid identification of genes associated with agronomic traits using GWAS and will accelerate future efforts aimed at crop improvement.
Journal Nat. Genet.
Country Japan
Volume 48(8)
Pages 927-34
Year 2016
PubMed ID 27322545
PubMed Central ID -
DOI 10.1038/ng.3596
URL -
Relation
Gene GATA28 HD2 HD6 HESO1 NAL1 RAE2 SE1
INSD -
Strain Wild Core Collection -
Induced Mutation Lines(NIG Collection) -
Sterile Seed Strain -
Lethal Embryo
Mutantion Strain
-
Stages in Each Organ
- Muant Lines (Gene)
-
Cultivated Varieties(NIG Collection) -
Stages in Each Organ -
/rice/oryzabase