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Reference
Author Wang H., Jiao X., Kong X., Hamera S., Wu Y., Chen X., Fang R., Yan Y.
Title A Signaling Cascade from miR444 to RDR1 in Rice Antiviral RNA Silencing Pathway.
Abstract:
Plant RNA-DEPENDENT RNA POLYMERASE1 (RDR1) is a key component of the antiviral RNA-silencing pathway, contributing to the biogenesis of virus-derived small interfering RNAs. This enzyme also is responsible for producing virus-activated endogenous small interfering RNAs to stimulate the broad-spectrum antiviral activity through silencing host genes. The expression of RDR1 orthologs in various plants is usually induced by virus infection. However, the molecular mechanisms of activation of RDR1 expression in response to virus infection remain unknown. Here, we show that a monocot-specific microRNA, miR444, is a key factor in relaying the antiviral signaling from virus infection to OsRDR1 expression. The expression of miR444 is enhanced by infection with Rice stripe virus (RSV), and overexpression of miR444 improves rice (Oryza sativa) resistance against RSV infection accompanied by the up-regulation of OsRDR1 expression.
Journal Plant Physiol.
Country unknown
Volume 170(4)
Pages 2365-77
Year 2016
PubMed ID 26858364
PubMed Central ID 4825140
DOI 10.1104/pp.15.01283
URL -
Relation
Gene MADS23 MADS27 MADS57 MIR444A RDR1
INSD -
Strain Wild Core Collection -
Induced Mutation Lines(NIG Collection) -
Sterile Seed Strain -
Lethal Embryo
Mutantion Strain
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Stages in Each Organ
- Muant Lines (Gene)
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Cultivated Varieties(NIG Collection) -
Stages in Each Organ -
/rice/oryzabase